Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Christine Gardiner"'
Autor:
Phillip C C Liu, Holly Koblish, Liangxing Wu, Kevin Bowman, Sharon Diamond, Darlise DiMatteo, Yue Zhang, Michael Hansbury, Mark Rupar, Xiaoming Wen, Paul Collier, Patricia Feldman, Ronald Klabe, Krista A Burke, Maxim Soloviev, Christine Gardiner, Xin He, Alla Volgina, Maryanne Covington, Bruce Ruggeri, Richard Wynn, Timothy C Burn, Peggy Scherle, Swamy Yeleswaram, Wenqing Yao, Reid Huber, Gregory Hollis
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231877 (2020)
Alterations in fibroblast growth factor receptor (FGFR) genes have been identified as potential driver oncogenes. Pharmacological targeting of FGFRs may therefore provide therapeutic benefit to selected cancer patients, and proof-of-concept has been
Externí odkaz:
https://doaj.org/article/f6f5510fe9c645f98e36ce8e4425a929
Autor:
Phillip C.C. Liu, Peggy Scherle, Gregory Hollis, Reid Huber, Andrew P. Combs, Wenqing Yao, Chu-Biao Xue, Swamy Yeleswaram, Bruce Ruggeri, Richard Wynn, Maryanne Covington, Yanlong Li, Xin He, Christine Gardiner, Pramod Thekkat, Valerie Dostalik, Patricia Feldman, Darlise DiMatteo, Padmaja Polam, Nikoo Falahatpisheh, Robert Collins, Jun Li, Xuesong Mike Liu, Huiqing Liu, Ravi Jalluri, Margaret Favata, Paul Waeltz, Nina Zolotarjova, Alla Volgina, Xiaoming Wen, Mark Rupar, Sharon Diamond, Thomas Maduskuie, Richard Sparks, Timothy C. Burn, Matthew C. Stubbs
Supplemental Tables 1 & 2 Supplemental Figure Legends Supplemental Figures 1 - 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9cd1caeb5c5e06cfd8b05f86b576b1
https://doi.org/10.1158/1078-0432.22475952
https://doi.org/10.1158/1078-0432.22475952
Autor:
Phillip C.C. Liu, Peggy Scherle, Gregory Hollis, Reid Huber, Andrew P. Combs, Wenqing Yao, Chu-Biao Xue, Swamy Yeleswaram, Bruce Ruggeri, Richard Wynn, Maryanne Covington, Yanlong Li, Xin He, Christine Gardiner, Pramod Thekkat, Valerie Dostalik, Patricia Feldman, Darlise DiMatteo, Padmaja Polam, Nikoo Falahatpisheh, Robert Collins, Jun Li, Xuesong Mike Liu, Huiqing Liu, Ravi Jalluri, Margaret Favata, Paul Waeltz, Nina Zolotarjova, Alla Volgina, Xiaoming Wen, Mark Rupar, Sharon Diamond, Thomas Maduskuie, Richard Sparks, Timothy C. Burn, Matthew C. Stubbs
Purpose:Bromodomain and extraterminal domain (BET) proteins regulate the expression of many cancer-associated genes and pathways; BET inhibitors have demonstrated activity in diverse models of hematologic and solid tumors. We report the preclinical c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67622e0fbfefceb9ea9cf87738b999fe
https://doi.org/10.1158/1078-0432.c.6529230.v1
https://doi.org/10.1158/1078-0432.c.6529230.v1
Autor:
Christine Gardiner, Anna Robuck, Jitka Becanova, Mark Cantwell, Sarit Kaserzon, David Katz, Jochen Mueller, Rainer Lohmann
Publikováno v:
Environmental toxicology and chemistry. 41(10)
Numerous per- and polyfluoroalkyl substances (PFAS) are of growing concern worldwide due to their ubiquitous presence, bioaccumulation and adverse effects. Surface waters in the United States have displayed elevated concentrations of PFAS, but so far
Autor:
Phillip M. Kopp, Christine Gardiner
Publikováno v:
Criminal Justice Studies. 34:289-305
Research finds that the public generally supports the use of Body-Worn Cameras (BWC) by police. Much of the support for BWCs is attributed to the technology’s ability to promote police accountabili...
Autor:
Christine Gardiner
Publikováno v:
Policing: A Journal of Policy and Practice. 15:798-816
This article describes the findings of a recent national survey of 958 local (municipal and county) law enforcement agencies on the subject of higher education in US policing. It is the first national study in 30 years to examine the issue and in 40
Autor:
Reid Huber, Maryanne Covington, Xin He, Paul Waeltz, Valerie Dostalik, Yanlong Li, Nina Zolotarjova, Chu-Biao Xue, Matthew C. Stubbs, Jun Li, Huiqing Liu, Peggy Scherle, Timothy Burn, Sharon Diamond, Thomas Maduskuie, Wenqing Yao, Padmaja Polam, Richard B. Sparks, Christine Gardiner, Xuesong Mike Liu, Robert Collins, Nikoo Falahatpisheh, Andrew P. Combs, Phillip Liu, Margaret Favata, Gregory Hollis, Richard Wynn, Swamy Yeleswaram, Bruce Ruggeri, Alla Volgina, Ravi Kumar Jalluri, Pramod Thekkat, Darlise DiMatteo, Patricia Feldman, Mark Rupar, Xiaoming Wen
Publikováno v:
Clinical Cancer Research. 25:300-311
Purpose: Bromodomain and extraterminal domain (BET) proteins regulate the expression of many cancer-associated genes and pathways; BET inhibitors have demonstrated activity in diverse models of hematologic and solid tumors. We report the preclinical
Autor:
Peggy Scherle, Timothy Burn, Sharon Diamond, Ronald M. Klabe, Wenqing Yao, Liangxing Wu, Reid Huber, Darlise DiMatteo, Alla Volgina, Kevin Bowman, Holly Koblish, Bruce Ruggeri, Xin He, Krista A. Burke, Yue Zhang, Swamy Yeleswaram, Christine Gardiner, Richard Wynn, Maxim Soloviev, Maryanne B. Covington, Gregory Hollis, Mark Rupar, Xiaoming Wen, Patricia Feldman, Michael Hansbury, Phillip C.C. Liu, Paul Collier
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231877 (2020)
PLoS ONE
PLoS ONE
Alterations in fibroblast growth factor receptor (FGFR) genes have been identified as potential driver oncogenes. Pharmacological targeting of FGFRs may therefore provide therapeutic benefit to selected cancer patients, and proof-of-concept has been
Autor:
Christine Gardiner, Jonathan Rios-Doria, Sunkyu Kim, Hui Wang, Yaoyu Chen, Elham Behshad, Yingnan Chen, Maryanne Covington, Alexander Sokolsky, Wenqing Yao, Kerri Lasky, Min Ye, Pramod Thekkat, Holly Koblish, Oleg Vechorkin, Luping Lin, Kristine Stump, Michelle Pusey, Karen Gallagher, Patricia Conlen, Mark Rupar
Publikováno v:
Cancer Research. 80:4513-4513
Antigen recognition and T-cell receptor (TCR) activation are fundamental processes that drive anti-tumor T cell responses. HPK1 has been identified as a negative regulator of TCR activation, as well as BCR activation, and is a potential anticancer ta