Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Christine F. O'Neill"'
Autor:
Sunil Sudarshan, Karthigayan Shanmugasundaram, Susan L Naylor, Shu Lin, Carolina B Livi, Christine F O'Neill, Dipen J Parekh, I-Tien Yeh, Lu-Zhe Sun, Karen Block
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21037 (2011)
Germline mutations of FH, the gene that encodes for the tricarboxylic acid TCA (TCA) cycle enzyme fumarate hydratase, are associated with an inherited form of cancer referred to as Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC). Individuals
Externí odkaz:
https://doaj.org/article/afe678de0b564340818bc772790d6cab
Autor:
Victor L. Sylvia, Courtney M. Creecy, Bernard P. Arulanandam, Rena Bizios, Christopher S. Navara, Christine F. O’Neill
Publikováno v:
Tissue Engineering Part A. 19:467-474
The present study addressed adult human mesenchymal stem cell (MSC) differentiation toward the osteoblastic lineage in response to alternating electric current, a biophysical stimulus. For this purpose, MSCs (chosen because of their proven capability
Autor:
Sean Eddy, Vickery Trinkaus-Randall, Karine Belguise, Xiaobo Wang, Nora D. Mineva, Dany Chalbos, Ziyang Yu, Gail E. Sonenshein, Mathilde Romagnoli, Christine F O'Neill, Nuria Sánchez-Morgan, Chengyin Min
Publikováno v:
Molecular and Cellular Biology. 29:3832-3844
Aberrant constitutive expression of NF-kappaB subunits, reported in more than 90% of breast cancers and multiple other malignancies, plays pivotal roles in tumorigenesis. Higher RelB subunit expression was demonstrated in estrogen receptor alpha (ERa
Autor:
Christina Cinelli, Jessica L. Toher, Alexis Lincoln, Robert J. Nadeau, Ruth G. Leon, Carla Mouta-Bellum, Robert Friesel, Christine F. O'Neill, Lucy Liaw, Sumithra Urs
Publikováno v:
The American Journal of Pathology. 171:1023-1036
Notch functions as an oncogene or tumor inhibitor in various cancers, and decreases in Notch2 expression are associated with increasing grade of human breast cancer. We constitutively activated Notch signaling with intracellular domain (ICD) expressi
Autor:
Diana Romero, Christine F. O'Neill, Volkhard Lindner, Lucy Liaw, Louise Brogan, Eric Tweedie, Barbara A. Conley, Ilka Pinz, Kira Young, Calvin P.H. Vary
Publikováno v:
Blood. 120(20)
BMP9 signaling has been implicated in hereditary hemorrhagic telangiectasia (HHT) and vascular remodeling, acting via the HHT target genes, endoglin and ALK1. This study sought to identify endothelial BMP9-regulated proteins that could affect the HHT
Publikováno v:
ASME 2012 Summer Bioengineering Conference, Parts A and B.
The present in vitro study was motivated by scientific literature reports that show enhanced healing of bone fractures in experimental animals in response to electrical stimulation. The underlying cellular- and molecular level mechanisms responsible
Autor:
Carolina B. Livi, Sunil Sudarshan, I-Tien Yeh, Christine F. O'Neill, Lu-Zhe Sun, Karen Block, Karthigayan Shanmugasundaram, S. Naylor, Dipen J. Parekh, Shu Lin
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21037 (2011)
PLoS ONE
PLoS ONE
Germline mutations of FH, the gene that encodes for the tricarboxylic acid TCA (TCA) cycle enzyme fumarate hydratase, are associated with an inherited form of cancer referred to as Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC). Individuals
Autor:
Lucy Liaw, Christine F. O'Neill, Igor Prudovsky, Ilka Pinz, Sumithra Urs, Yuefang Tang, Alice Roudabush, Deena Small, Doreen Kacer
We previously found that soluble forms of the Notch ligands Jagged1 and Delta1 induced fibroblast growth factor receptor-dependent cell transformation in NIH3T3 fibroblasts. However, the phenotypes of these lines differed, indicating distinct functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd42a984acada10d30bd724dcb222fc1
https://europepmc.org/articles/PMC2527077/
https://europepmc.org/articles/PMC2527077/
Publikováno v:
Thrombosis and haemostasis. 96(3)
SummaryVascular smooth muscle cell (VSMC) proliferation occurs in vascular obstructive events such as atherosclerosis and restenosis. We previously showed that Notch receptors are induced in smooth muscle cells during vascular remodeling. Our goal wa