Výsledky vyhledávání - "Christine F. Hoyle"

Expansion of Philadelphia Chromosome–Negative CD3+CD56+ Cytotoxic Cells From Chronic Myeloid Leukemia Patients: In Vitro and In Vivo Efficacy in Severe Combined Immunodeficiency Disease Mice

Autor: Christine F. Hoyle, Charles D. Bangs, Pearl Chang, Onsi W. Kamel, Bela A. Mehta, Robert S. Negrin

Publikováno v: Blood. 92:3318-3327

We have developed culture conditions for the efficient expansion of cytotoxic effector cells from peripheral blood mononuclear cells (PBMNCs) by the timed addition of interferon-γ (IFN-γ), interleukin-2 (IL-2), and the monoclonal antibody (MoAb) OK

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe04497a93118209e1233445edeb05ea
https://doi.org/10.1182/blood.v92.9.3318

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Engraftment of chronic myeloid leukemia in SCID mice

Autor: Robert S. Negrin, Christine F. Hoyle

Publikováno v: Hematological Oncology. 16:87-100

Chronic myeloid leukemia (CML) is a clonal disorder of primitive hematopoietic stem cells characterized by a reciprocal translocation between chromosomes 9 and 22. Animal models of CML would be useful to study the biology and potential therapies in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::50c1fbeebb71ce70720392c04af42c8c
https://doi.org/10.1002/(sici)1099-1069(199809)16:3<87::aid-hon626>3.0.co

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Multiple cycles of high dose chemotherapy supported by hematopoietic progenitor cells as treatment for patients with advanced malignancies

Autor: Jeffrey Schriber, Claus R. Kusnierz-Glaz, Christine F. Hoyle, Gwynn D. Long, Nelson J. Chao, Karl G. Blume, Robert S. Negrin

Publikováno v: Cancer. 76:860-868

BACKGROUND Retrospective studies suggest that dose intensity is an important determinant of outcome in the treatment of patients with a variety of malignant diseases such as breast cancer, ovarian cancer, and lymphoma. Unfortunately, these results ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4109ba2e3deea04c752122ddcbda0f34
https://doi.org/10.1002/1097-0142(19950901)76:5<860::aid-cncr2820760521>3.0.co

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Transplantation of enriched and purged peripheral blood progenitor cells from a single apheresis product in patients with non-Hodgkin's lymphoma

Autor: Jeffrey Schriber, Byron W. Brown, Claus R. Kusnierz-Glaz, Nelson J. Chao, BJ Still, Wendy W. Hu, Gwynn D. Long, Robert S. Negrin, Sandra J. Horning, Christine F. Hoyle

Publikováno v: Blood. 85:3334-3341

High-dose chemotherapy with or without radiotherapy followed by autologous transplantation of hematopoietic progenitor cells is an effective treatment for patients with high-risk or relapsed non- Hodgkin's lymphoma. Chemotherapy and/or hematopoietic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aeda392b2cbf04c353883568018b5183
https://doi.org/10.1182/blood.v85.11.3334.bloodjournal85113334

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