Výsledky vyhledávání - "Christine E. Nickerson"

Reduction of Simian-Human Immunodeficiency Virus 89.6P Viremia in Rhesus Monkeys by Recombinant Modified Vaccinia Virus Ankara Vaccination

Autor: Rebekah Zin, Linda S. Wyatt, David C. Montefiori, Michelle A. Lifton, Marcelo J. Kuroda, Alicia Buckler-White, Dan H. Barouch, Vanessa M. Hirsch, Alicia Gaitan, Jörn E. Schmitz, Sampa Santra, Jae-Hwan Nam, Ronald J. Plishka, Norman L. Letvin, Bernard Moss, Christine E. Nickerson

Publikováno v: Journal of Virology. 75:5151-5158

Since cytotoxic T lymphocytes (CTLs) are critical for controlling human immunodeficiency virus type 1 (HIV-1) replication in infected individuals, candidate HIV-1 vaccines should elicit virus-specific CTL responses. In this report, we study the immun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1366afc423503e661b4bbb647fc0bcd5
https://doi.org/10.1128/jvi.75.11.5151-5158.2001

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Preservation of Lymphocyte Immunophenotype and Proliferative Responses in Cryopreserved Peripheral Blood Mononuclear Cells from Human Immunodeficiency Virus Type 1-Infected Donors: Implications for Multicenter Clinical Trials

Autor: Christine E. Nickerson, Miriam Chernoff, Keith A. Reimann, Alan L. Landay, Cynthia L. Wilkening

Publikováno v: Clinical Diagnostic Laboratory Immunology. 7:352-359

Human immunodeficiency virus type 1 (HIV-1) infection results in impaired immune function that can be measured by changes in immunophenotypically defined lymphocyte subsets and other in vitro functional assays. These in vitro assays may also serve as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3347f9580c78bf5f97719c7689b7b900
https://doi.org/10.1128/cdli.7.3.352-359.2000

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Augmentation of immune responses to HIV-1 and simian immunodeficiency virus DNA vaccines by IL-2/Ig plasmid administration in rhesus monkeys

Publikováno v: Proceedings of the National Academy of Sciences. 97:4192-4197

The potential utility of plasmid DNA as an HIV-1 vaccination modality currently is an area of active investigation. However, recent studies have raised doubts as to whether plasmid DNA alone will elicit immune responses of sufficient magnitude to pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d37aeccf743bbcf9c7bb22ec45819f7
https://doi.org/10.1073/pnas.050417697

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Comparative Analysis of Cytotoxic T Lymphocytes in Lymph Nodes and Peripheral Blood of Simian Immunodeficiency Virus-Infected Rhesus Monkeys

Autor: Carol I. Lord, Jörn E. Schmitz, William A. Charini, Norman L. Letvin, Marcelo J. Kuroda, Christine E. Nickerson, Meryl A. Forman

Publikováno v: Journal of Virology. 73:1573-1579

Most studies of human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T lymphocytes (CTL) have been confined to the evaluation of these effector cells in the peripheral blood. What has not been clear is the extent to which CTL activity in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0828540aa8157e8c3591c92e69b19abf
https://doi.org/10.1128/jvi.73.2.1573-1579.1999

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Recombinant canarypox vaccine-elicited CTL specific for dominant and subdominant simian immunodeficiency virus epitopes in rhesus monkeys

Autor: Jörn E. Schmitz, Genoveffa Franchini, Carol I. Lord, Christine E. Nickerson, Sampa Santra, Norman L. Letvin, Ranajit Pal, Marcelo J. Kuroda, Michelle A. Lifton

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 168(4)

Since virus-specific CTL play a central role in containing HIV replication, a candidate AIDS vaccine should generate virus-specific CTL responses. In this study, the ability of a recombinant canarypox virus expressing SIV Gag-Pol-Env (ALVAC/SIV gag-p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::941ad0eb874ada969ebb46f4458a066d
https://pubmed.ncbi.nlm.nih.gov/11823518

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Simian immunodeficiency virus (SIV)-specific cytotoxic T lymphocytes in gastrointestinal tissues of chronically SIV-infected rhesus monkeys

Autor: Aruna Seth, Ronald S. Veazey, Andrew A. Lackner, Xavier Alvarez, Norman L. Letvin, Jörn E. Schmitz, Christine E. Nickerson, Michelle A. Lifton, Marcelo J. Kuroda, Daniel B. Levy, Keith G. Mansfield

Publikováno v: Blood. 98(13)

Although systemic virus-specific cytotoxic T lymphocyte (CTL) responses are of critical importance in controlling virus replication in individuals infected with human immunodeficiency virus 1 (HIV-1), little is known about this immune response in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a7e8bca26616065bd167896b8ff7a14
https://pubmed.ncbi.nlm.nih.gov/11739183

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Simian immunodeficiency virus (SIV)-specific CTL are present in large numbers in livers of SIV-infected rhesus monkeys

Autor: Jörn E. Schmitz, Peter J. Dailey, Wesley M. Taylor, Paul Racz, Meryl A. Forman, Christine E. Nickerson, Ronald S. Veazey, Marcelo J. Kuroda, Norman L. Letvin, Aruna Seth, Michelle A. Lifton, Klara Tenner-Racz

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 164(11)

The immunopathogenesis of AIDS-associated hepatitis was explored in the SIV/rhesus monkey model. The livers of SIV-infected monkeys showed a mild hepatitis, with a predominantly CD8+ T lymphocyte infiltration in the periportal fields and sinusoids. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574676af3ceb8cc3980fa62c0b4eab7c
https://pubmed.ncbi.nlm.nih.gov/10820285

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