Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Christine E. Larkins"'
Autor:
Jane Brennan, Kirk M. McHugh, Christine E. Larkins, Chad M. Vezina, Carrie B. Wiese, Kerry Schneider, Richard Baldock, Jamie A. Davies, Jane F. Armstrong, Melissa H. Little, Janet R. Keast, Martin J. Cohn, Kylie Georgas, Simon D. Harding, E. Michelle Southard-Smith, Cathy Mendelsohn, Ekatherina Batourina, Hanbin Dan, Dennis P. Buehler
Publikováno v:
Development. 142:1893-1908
Malformation of the urogenital tract represents a considerable paediatric burden, with many defects affecting the lower urinary tract (LUT), genital tubercle and associated structures. Understanding the molecular basis of such defects frequently draw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ccdfd37547ed26028ec7b3855848b3d
https://doi.org/10.1242/dev.117903
https://doi.org/10.1242/dev.117903
Autor:
Martin J. Cohn, Christine E. Larkins
Publikováno v:
Sexual Development. 9:34-42
Development of a phallus occurs in almost all amniotes; however, considerable variation in phallus morphology among different amniote lineages has contributed to the debate about their structural homology. Mammals are the only amniotes that form a cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::692c2153cc989c408c18dbd5bbd36d43
https://doi.org/10.1159/000363631
https://doi.org/10.1159/000363631
Disorders of sex development (DSDs) are congenital anomalies that affect sexual differentiation of genitourinary organs and secondary sex characters. A common cause of female genital virilization is congenital adrenal hyperplasia (CAH), in which exce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c81926afd3b7628992184a1f025899ca
https://europepmc.org/articles/PMC5127369/
https://europepmc.org/articles/PMC5127369/
Autor:
Michael P. East, Tamara Caspary, Richard A. Kahn, Gladys D. Gonzalez Aviles, Christine E. Larkins
Publikováno v:
Molecular Biology of the Cell
We show Arl13b is localized to the ciliary membrane and regulates tubulin modifications and ciliary length in vitro. Significantly, we found that Smoothened is enriched in Arl13b null fibroblasts, even without Sonic hedgehog stimulation, but that Gli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8637b66d9746a84214e8ad03dd53b4d2
https://doi.org/10.1091/mbc.e10-12-0994
https://doi.org/10.1091/mbc.e10-12-0994
Autor:
Thomas J. Sanger, Christine E. Larkins, A. Kelsey Lewis, Francisca Leal, Martin J. Cohn, Claire L. Perriton, Marissa L. Gredler, Ana M. Herrera
Publikováno v:
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation. 8(5)
External genitalia are found in each of the major clades of amniotes. The phallus is an intromittent organ that functions to deliver sperm into the female reproductive tract for internal fertilization. The cellular and molecular genetic mechanisms of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30e734ea01f51566f513f127d135d864
https://pubmed.ncbi.nlm.nih.gov/25115961
https://pubmed.ncbi.nlm.nih.gov/25115961
Autor:
Christine E, Larkins, Martin J, Cohn
Publikováno v:
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation. 9(1)
Development of a phallus occurs in almost all amniotes; however, considerable variation in phallus morphology among different amniote lineages has contributed to the debate about their structural homology. Mammals are the only amniotes that form a cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4e7b8ed7c7584a3a1698ab402734b62
https://pubmed.ncbi.nlm.nih.gov/24969757
https://pubmed.ncbi.nlm.nih.gov/24969757
Autor:
Michael J. Hillman, Tamara Caspary, Christine E. Larkins, Billie A. Moore, Gladys D. Gonzalez Aviles
Publikováno v:
Mammalian genome : official journal of the International Mammalian Genome Society. 21(7-8)
Mitochondria are dynamic cellular organelles that balance fission and fusion to regulate organelle morphology, distribution, and activity, and Opa1 is one of three GTPases known to regulate mitochondrial fusion. In humans, loss of a single Opa1 allel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b24f70b285b245d260b1be103cd8bd28
https://pubmed.ncbi.nlm.nih.gov/20652258
https://pubmed.ncbi.nlm.nih.gov/20652258
Publikováno v:
Developmental cell. 12(5)
SUMMARY Several studies have linked cilia and Hedgehog signaling, but the precise roles of ciliary proteins in signal transduction remain enigmatic. Here we describe a mouse mutation, hennin (hnn), that causes coupled defects in cilia structure and S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b794e8535ad35d1cd934aa0d9b97a8ed
https://pubmed.ncbi.nlm.nih.gov/17488627
https://pubmed.ncbi.nlm.nih.gov/17488627
Autor:
Scott E. Devine, Circe Tsui, Christine E. Larkins, Adam D. Beauchamp, Ryan E. Mills, Christopher T. Luttig, W. Stephen Pittard
Publikováno v:
Genome research. 16(9)
Although many studies have been conducted to identify single nucleotide polymorphisms (SNPs) in humans, few studies have been conducted to identify alternative forms of natural genetic variation, such as insertion and deletion (INDEL) polymorphisms.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::521f5fbd534ec951844e4be9064b768b
https://pubmed.ncbi.nlm.nih.gov/16902084
https://pubmed.ncbi.nlm.nih.gov/16902084
Publikováno v:
International Journal of Developmental Neuroscience. 28:645-645
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f04c1d7c5a24003738575d0f826b332
https://doi.org/10.1016/j.ijdevneu.2010.07.016
https://doi.org/10.1016/j.ijdevneu.2010.07.016