Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Christine E. Hellweg"'
Autor:
Trent Davis, Kevin Tabury, Shouan Zhu, Debora Angeloni, Sarah Baatout, Alexandra Benchoua, Juergen Bereiter-Hahn, Daniele Bottai, Judith-Irina Buchheim, Marco Calvaruso, Eugénie Carnero-Diaz, Sara Castiglioni, Duccio Cavalieri, Gabriele Ceccarelli, Alexander Choukér, Francesca Cialdai, Gianni Ciofani, Giuseppe Coppola, Gabriella Cusella, Andrea Degl’Innocenti, Jean-Francois Desaphy, Jean-Pol Frippiat, Michael Gelinsky, Giada Genchi, Maria Grano, Daniela Grimm, Alain Guignandon, Christiane Hahn, Jason Hatton, Raúl Herranz, Christine E. Hellweg, Carlo Saverio Iorio, Thodoris Karapantsios, Jack J.W.A. van Loon, Matteo Lulli, Jeanette Maier, Jos Malda, Emina Mamaca, Lucia Morbidelli, Angelique van Ombergen, Andreas Osterman, Aleksandr Ovsianikov, Francesco Pampaloni, Elizabeth Pavezlorie, Veronica Pereda-Campos, Cyrille Przybyla, Christopher Puhl, Petra Rettberg, Angela Maria Rizzo, Kate Robson-Brown, Leonardo Rossi, Giorgio Russo, Alessandra Salvetti, Daniela Santucci, Matthias Sperl, Sara Tavella, Christiane Thielemann, Ronnie Willaert, Nathaniel Szewczyk, Monica Monici
Publikováno v:
npj Microgravity, Vol 10, Iss 1, Pp 1-7 (2024)
Abstract Progress in mechanobiology allowed us to better understand the important role of mechanical forces in the regulation of biological processes. Space research in the field of life sciences clearly showed that gravity plays a crucial role in bi
Externí odkaz:
https://doaj.org/article/3889d8bf9e7845629cdd36ecd78d8e8d
Autor:
Francesca Cialdai, Austin M. Brown, Cory W. Baumann, Debora Angeloni, Sarah Baatout, Alexandra Benchoua, Juergen Bereiter-Hahn, Daniele Bottai, Judith-Irina Buchheim, Marco Calvaruso, Eugénie Carnero-Diaz, Sara Castiglioni, Duccio Cavalieri, Gabriele Ceccarelli, Alexander Choukér, Gianni Ciofani, Giuseppe Coppola, Gabriella Cusella, Andrea Degl’Innocenti, Jean-Francois Desaphy, Jean-Pol Frippiat, Michael Gelinsky, Giada Genchi, Maria Grano, Daniela Grimm, Alain Guignandon, Christiane Hahn, Jason Hatton, Raúl Herranz, Christine E. Hellweg, Carlo Saverio Iorio, Thodoris Karapantsios, Jack van Loon, Matteo Lulli, Jeanette Maier, Jos Malda, Emina Mamaca, Lucia Morbidelli, Angelique van Ombergen, Andreas Osterman, Aleksandr Ovsianikov, Francesco Pampaloni, Elizabeth Pavezlorie, Veronica Pereda-Campos, Cyrille Przybyla, Christopher Puhl, Petra Rettberg, Chiara Risaliti, Angela Maria Rizzo, Kate Robson-Brown, Leonardo Rossi, Giorgio Russo, Alessandra Salvetti, Daniela Santucci, Matthias Sperl, Felice Strollo, Kevin Tabury, Sara Tavella, Christiane Thielemann, Ronnie Willaert, Nathaniel J. Szewczyk, Monica Monici
Publikováno v:
npj Microgravity, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract The present white paper concerns the indications and recommendations of the SciSpacE Science Community to make progress in filling the gaps of knowledge that prevent us from answering the question: “How Do Gravity Alterations Affect Animal
Externí odkaz:
https://doaj.org/article/4a660d7310bb459cbd6279d750439b69
Autor:
Hasan Nisar, Paulina Mercedes Sanchidrián González, Frederik M. Labonté, Claudia Schmitz, Marie Denise Roggan, Jessica Kronenberg, Bikash Konda, François Chevalier, Christine E. Hellweg
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4495 (2024)
Cellular hypoxia, detectable in up to 80% of non-small cell lung carcinoma (NSCLC) tumors, is a known cause of radioresistance. High linear energy transfer (LET) particle radiation might be effective in the treatment of hypoxic solid tumors, includin
Externí odkaz:
https://doaj.org/article/c00f9bfd1bc448068267752350d53aa5
Autor:
Anna Fogtman, Sarah Baatout, Bjorn Baselet, Thomas Berger, Christine E. Hellweg, Piers Jiggens, Chiara La Tessa, Livio Narici, Petteri Nieminen, Laure Sabatier, Giovanni Santin, Uwe Schneider, Ulrich Straube, Kevin Tabury, Walter Tinganelli, Linda Walsh, Marco Durante
Publikováno v:
npj Microgravity, Vol 9, Iss 1, Pp 1-6 (2023)
Abstract Human spaceflight is entering a new era of sustainable human space exploration. By 2030 humans will regularly fly to the Moon’s orbit, return to the Moon’s surface and preparations for crewed Mars missions will intensify. In planning the
Externí odkaz:
https://doaj.org/article/6eb54f09f483400fa1e2ad71dfd5cb0b
Autor:
Hasan Nisar, Frederik M. Labonté, Marie Denise Roggan, Claudia Schmitz, François Chevalier, Bikash Konda, Sebastian Diegeler, Christa Baumstark-Khan, Christine E. Hellweg
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1010 (2024)
Hypoxia-induced radioresistance reduces the efficacy of radiotherapy for solid malignancies, including non-small cell lung cancer (NSCLC). Cellular hypoxia can confer radioresistance through cellular and tumor micro-environment adaptations. Until rec
Externí odkaz:
https://doaj.org/article/3acefac0701f44f08af6ee7bd7b356d5
Autor:
Marie Denise Roggan, Jessica Kronenberg, Esther Wollert, Sven Hoffmann, Hasan Nisar, Bikash Konda, Sebastian Diegeler, Christian Liemersdorf, Christine E. Hellweg
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
IntroductionExposure to space conditions during crewed long-term exploration missions can cause several health risks for astronauts. Space radiation, isolation and microgravity are major limiting factors. The role of astrocytes in cognitive disturban
Externí odkaz:
https://doaj.org/article/098a5f6e27a34789a6a117f67dfdb1eb
Autor:
Hasan Nisar, Paulina Mercedes Sanchidrián González, Melanie Brauny, Frederik M. Labonté, Claudia Schmitz, Marie Denise Roggan, Bikash Konda, Christine E. Hellweg
Publikováno v:
Cancers, Vol 15, Iss 9, p 2472 (2023)
Hypoxia occurs in 80% of non-small cell lung carcinoma (NSCLC) cases, leading to treatment resistance. Hypoxia’s effects on NSCLC energetics are not well-characterized. We evaluated changes in glucose uptake and lactate production in two NSCLC cell
Externí odkaz:
https://doaj.org/article/fdedbb83832046a08499066fd9803194
Autor:
Eftychia Sagkrioti, Gökay Mehmet Biz, Işıl Takan, Seyedehsadaf Asfa, Zacharenia Nikitaki, Vassiliki Zanni, Rumeysa Hanife Kars, Christine E. Hellweg, Edouard I. Azzam, Stella Logotheti, Athanasia Pavlopoulou, Alexandros G. Georgakilas
Publikováno v:
Antioxidants, Vol 11, Iss 11, p 2286 (2022)
Ionizing radiation (IR) is a genuine genotoxic agent and a major modality in cancer treatment. IR disrupts DNA sequences and exerts mutagenic and/or cytotoxic properties that not only alter critical cellular functions but also impact tissues proximal
Externí odkaz:
https://doaj.org/article/716a90b4c9414974846ec05c77ddc045
Autor:
Sebastian Feles, Christian Overath, Sina Reichardt, Sebastian Diegeler, Claudia Schmitz, Jessica Kronenberg, Christa Baumstark-Khan, Ruth Hemmersbach, Christine E. Hellweg, Christian Liemersdorf
Publikováno v:
Methods and Protocols, Vol 5, Iss 4, p 58 (2022)
The neuroblastoma cell line SH-SY5Y has been a well-established and very popular in vitro model in neuroscience for decades, especially focusing on neurodevelopmental disorders, such as Parkinson’s disease. The ability of this cell type to differen
Externí odkaz:
https://doaj.org/article/51ed9a079fb24768a6406ca2d7ccf977
Autor:
David S. Kim, Tobias Weber, Ulrich Straube, Christine E. Hellweg, Mona Nasser, David A. Green, Anna Fogtman
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
There is a need to investigate new countermeasures against the detrimental effects of ionizing radiation as deep space exploration missions are on the horizon.Objective: In this systematic review, the effects of physical exercise upon ionizing radiat
Externí odkaz:
https://doaj.org/article/09773a8edfd34371a5cbe47fab397278