Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Christine E Gee"'
Autor:
Daniel eHoyer, Thomas eDürst, Markus eFendt, Laura H Jacobson, Claudia eBetschart, Samuel eHintermann, Dirk eBehnke, Simona eCotesta, Grit eLaue, Silvio eOfner, Eric eLegangneux, Christine E Gee
Publikováno v:
Frontiers in Neuroscience, Vol 7 (2013)
Dual orexin receptor (OXR) antagonists (DORAs) such as almorexant, SB-649868, suvorexant (MK-4305) and filorexant (MK-6096), have shown promise for the treatment of insomnias and sleep disorders. Whether antagonism of both OX1R and OX2R is necessary
Externí odkaz:
https://doaj.org/article/83dd9405703d4245af02f4011cce40ee
Autor:
Frederique Chaperon, Markus Fendt, Peter H Kelly, Kurt Lingenhoehl, Johannes Mosbacher, Hans-Rudolf Olpe, Peter Schmid, Christine Sturchler, Kevin H McAllister, P Herman van der Putten, Christine E Gee
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34963 (2012)
Links between synaptic plasticity in the lateral amygdala (LA) and Pavlovian fear learning are well established. Neuropeptides including gastrin-releasing peptide (GRP) can modulate LA function. GRP increases inhibition in the LA and mice lacking the
Externí odkaz:
https://doaj.org/article/354b10421eb1418bbc11936d8893865b
Autor:
Marina Wendlandt, Alina J. Kürten, Antonia Beiersdorfer, Charlotte Schubert, Kiana Samad-Yazdtchi, Jessica Sauer, M. Carolina Pinto, Kristina Schulz, Manuel A. Friese, Christine E. Gee, Daniela Hirnet, Christian Lohr
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe cyclic nucleotide cyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger, which is known to play an important anti-inflammatory role. Astrocytes in the central nervous system (CNS) can modulate inflammation but little
Externí odkaz:
https://doaj.org/article/4efe47dd39af48f7be496c62d1ac970c
Autor:
Paul J. Lamothe-Molina, Andreas Franzelin, Lennart Beck, Dong Li, Lea Auksutat, Tim Fieblinger, Laura Laprell, Joachim Alhbeck, Christine E. Gee, Matthias Kneussel, Andreas K. Engel, Claus C. Hilgetag, Fabio Morellini, Thomas G. Oertner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
In mice, reactivation of neurons that express cFos during fear conditioning induces a behavioural response. Here the authors show that cFos expression in mouse dentate gyrus shifts every day to different neurons, even during highly consistent spatial
Externí odkaz:
https://doaj.org/article/3533e982510d493eb9e861a533fcd010
Autor:
Kira V. Gromova, Edda Thies, Philipp C. Janiesch, Felix P. Lützenkirchen, Yipeng Zhu, Daniele Stajano, Céline D. Dürst, Michaela Schweizer, Anja Konietzny, Marina Mikhaylova, Christine E. Gee, Matthias Kneussel
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112743- (2023)
Summary: Homeostatic synaptic plasticity adjusts the strength of synapses to restrain neuronal activity within a physiological range. Postsynaptic guanylate kinase-associated protein (GKAP) controls the bidirectional synaptic scaling of AMPA receptor
Externí odkaz:
https://doaj.org/article/b4ea89a9a8004deeb934439ce397a69b
Autor:
Brenna C. Fearey, Lars Binkle, Daniel Mensching, Christian Schulze, Christian Lohr, Manuel A. Friese, Thomas G. Oertner, Christine E. Gee
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The transient receptor potential melastatin 4 (TRPM4) channel contributes to disease severity in the murine experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis and to neuronal cell death in models of excitotoxicity an
Externí odkaz:
https://doaj.org/article/3bd731c3c1254a9889512194675bf219
Autor:
Shang Yang, Oana M. Constantin, Divya Sachidanandan, Hannes Hofmann, Tobias C. Kunz, Vera Kozjak-Pavlovic, Thomas G. Oertner, Georg Nagel, Robert J. Kittel, Christine E. Gee, Shiqiang Gao
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-17 (2021)
Abstract Background Cyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger that transduces extracellular signals in virtually all eukaryotic cells. The soluble Beggiatoa photoactivatable adenylyl cyclase (bPAC) rapidly raises cAMP in
Externí odkaz:
https://doaj.org/article/57f6f60c5a00494697861315cebe0994
Autor:
Fei Chen, Xiaodong Duan, Yao Yu, Shang Yang, Yuanyuan Chen, Christine E. Gee, Georg Nagel, Kang Zhang, Shiqiang Gao, Yin Shen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/fcfeacb61b23499ebb7d29d8557d9ab7
Autor:
Alberto Perez-Alvarez, Brenna C. Fearey, Ryan J. O’Toole, Wei Yang, Ignacio Arganda-Carreras, Paul J. Lamothe-Molina, Benjamien Moeyaert, Manuel A. Mohr, Lauren C. Panzera, Christian Schulze, Eric R. Schreiter, J. Simon Wiegert, Christine E. Gee, Michael B. Hoppa, Thomas G. Oertner
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Calcium imaging has been used to visualize the activity of individual synapses, but cannot be scaled up to monitor thousands of synapses in tissue. Here, the authors present genetic tools that can be photoconverted from green to red to create a map o
Externí odkaz:
https://doaj.org/article/7d7a281a0ac548d19a0654bd5702913e
Autor:
Christian Lohr, Antonia Beiersdorfer, Timo Fischer, Daniela Hirnet, Natalie Rotermund, Jessica Sauer, Kristina Schulz, Christine E. Gee
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Ca2+ imaging is the most frequently used technique to study glial cell physiology. While chemical Ca2+ indicators served to visualize and measure changes in glial cell cytosolic Ca2+ concentration for several decades, genetically encoded Ca2+ indicat
Externí odkaz:
https://doaj.org/article/68c930d6ca174b7388de6584b00af867