Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Christine Deppong"'
Publikováno v:
The Journal of Immunology. 186:63.22-63.22
Optimal T cell activation requires both TCR signaling and costimulation through CD28. In vivo use of the drug CTLA4Ig (Abatacept) interrupts B7:CD28 binding and has been an effective therapeutic strategy for chronic inflammatory disease. The presumed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ba7d83bff4e60f53ef2ce2d1b95bc57
https://doi.org/10.4049/jimmunol.186.supp.63.22
https://doi.org/10.4049/jimmunol.186.supp.63.22
Autor:
Jonathan Boomer, Kathleen To, Traci Bricker, Christine Deppong, Katherine Chang, Andrew Walton, Dale Osborne, Seth Crockford, Paul Swanson, Richard Hotchkiss, Jonathan Green
Publikováno v:
The Journal of Immunology. 186:99.9-99.9
Approximately 200,000 people die annually in the US from sepsis. Sepsis is characterized by an acute “cytokine storm” followed by an immune suppressed state. While apoptosis of innate and adaptive immune cells has been demonstrated, the mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::feaf8be585ec49e2fb315ca41d77b3a5
https://doi.org/10.4049/jimmunol.186.supp.99.9
https://doi.org/10.4049/jimmunol.186.supp.99.9
Autor:
Jonathan Boomer, Christine Deppong, Lindzy Dodson, Dulari Shah, Traci Bricker, Jonathan Green
Publikováno v:
The Journal of Immunology. 184:50.24-50.24
T cell activation requires signaling through the TcR and engagement of a costimulatory receptor. CD28 is the most important costimulatory receptor; however, the signaling pathways initiated by CD28 remain highly controversial. To examine this, we gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c95ab72659af88aa5603a06a6f29c68
https://doi.org/10.4049/jimmunol.184.supp.50.24
https://doi.org/10.4049/jimmunol.184.supp.50.24