Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Christine D. Krempl"'
Publikováno v:
Emerging Infectious Diseases, Vol 19, Iss 6, Pp 1029-1030 (2013)
Externí odkaz:
https://doaj.org/article/dcbae0af0d1843b589caa84629e4f13c
Autor:
Christine D. Krempl, Kirsten Glaser, Christian P. Speer, Silvia Seidenspinner, Markus Fehrholz, Steffen Kunzmann
Publikováno v:
Influenza and Other Respiratory Viruses
Respiratory syncytial virus (RSV) is a leading cause of severe lower respiratory tract infection in early childhood. Underlying pathomechanisms of elevated pulmonary morbidity in later infancy are largely unknown. We found that RSV-infected H441 cell
Publikováno v:
Journal of Virology
Pneumonia virus of mice (PVM), a relative of human respiratory syncytial virus (RSV), causes respiratory disease in mice. There is serologic evidence suggesting widespread exposure of humans to PVM. To investigate replication in primates, African gre
Publikováno v:
Journal of Virology. 85:10135-10143
Susceptibility to respiratory syncytial virus (RSV) infection in mice is genetically determined. While RSV causes little pathology in C57BL/6 mice, pulmonary inflammation and weight loss occur in BALB/c mice. Using major histocompatibility complex (M
Autor:
Stefanie Frey, Christine D. Krempl, Ursula J. Buchholz, Stephan Ehl, Britta Heinze, Anette Schmitt-Gräff, Peter Staeheli, Markus Mordstein, Peter L. Collins
Publikováno v:
Journal of Virology. 85:4071-4084
Infection of mice with pneumonia virus of mice (PVM) provides a convenient experimental pathogenesis model in a natural host for a human respiratory syncytial virus-related virus. Extending our previous work showing that the PVM nonstructural (NS) pr
Autor:
Eva Jüttner, Ulrike V. Gerlach, Andreas Beilhack, Alf Zerweck, Konrad Wilhelm, Neeraja Kambham, Tobias Müller, Francesco Di Virgilio, Jürgen Finke, Paul Fisch, Robert Zeiser, Christine D. Krempl, Marco Idzko, Christoph Dürr, Davide Ferrari, Patrizia Pellegatti, Melanie Grimm, Stephan Sorichter, Jayanthi Ganesan, Frank Gärtner
Publikováno v:
Nature Medicine. 16:1434-1438
Danger signals released upon cell damage can cause excessive immune-mediated tissue destruction such as that found in acute graft-versus-host disease (GVHD), allograft rejection and systemic inflammatory response syndrome. Given that ATP is found in
Autor:
Peter L. Collins, Jerrold M. Ward, Christine D. Krempl, Ursula J. Buchholz, Britta Heinze, Elaine W. Lamirande
Publikováno v:
Journal of Virology. 83:1969-1980
Pneumonia virus of mice (PVM) strain 15 causes fatal pneumonia in mice and provides a convenient model for human respiratory syncytial virus pathogenesis and immunobiology. We prepared PVM mutants lacking the genes for nonstructural proteins NS1 and/
Publikováno v:
Journal of Virology. 82:11619-11627
Infection of mice with pneumonia virus of mice (PVM) is used as a natural host experimental model for studying the pathogenesis of infection with the closely related human respiratory syncytial virus. We analyzed the contribution of T cells to virus
Autor:
Christine D. Krempl, Ursula J. Buchholz, Giw Nayebagha, Elaine W. Lamirande, Anna Wnekowicz, Peter L. Collins
Publikováno v:
Journal of Virology. 81:9490-9501
Pneumonia virus of mice (PVM) is a murine relative of human respiratory syncytial virus (HRSV). Here we developed a reverse genetics system for PVM based on a consensus sequence for virulent strain 15. Recombinant PVM and a version engineered to expr
Autor:
Christine D. Krempl, Stefanie Frey, Hanspeter Pircher, Peter Collins, Marie Follo, Stephan Ehl
Cytotoxic T cells (CTL) play a critical role in the clearance of respiratory viral infections, but they also contribute to disease manifestations. In this study, we infected mice with a genetically modified pneumonia virus of mice (PVM) that allowed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95480610119d60f70716d8e29bc57300
https://europepmc.org/articles/PMC3807307/
https://europepmc.org/articles/PMC3807307/