Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Christine D, Pozniak"'
Autor:
Robert Mintzer, Sreemathy Ramaswamy, Kinjalkumar Shah, Rami N Hannoush, Christine D Pozniak, Frederick Cohen, Xianrui Zhao, Emile Plise, Joseph W Lewcock, Christopher E Heise
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30376 (2012)
Caspase-6 is a cysteinyl protease implicated in neurodegenerative conditions including Alzheimer's and Huntington's disease making it an attractive target for therapeutic intervention. A greater understanding of the role of caspase-6 in disease has b
Externí odkaz:
https://doaj.org/article/de49ec19875a41d9aa52b7a1c4028046
Autor:
Christine D. Pozniak, Abraham J. Langseth, Zena Werb, Samuel J. Pleasure, Gerrit J. P. Dijkgraaf, Youngshik Choe
Publikováno v:
Proceedings of the National Academy of Sciences. 107:21795-21800
Oligodendrocyte precursor cells (OPCs) are lineage-restricted progenitors generally limited in vivo to producing oligodendrocytes. Mechanisms controlling genesis of OPCs are of interest because of their importance in myelin development and their pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eea8040370c92d64cc7213ad017ef888
https://doi.org/10.1073/pnas.1016485107
https://doi.org/10.1073/pnas.1016485107
Autor:
Christine D. Pozniak, Trung Huynh, Samuel J. Pleasure, Abraham J. Langseth, Roeben N. Munji, Youngshik Choe
Publikováno v:
The Journal of Neuroscience. 30:13367-13372
Oligodendrocyte precursor cells (OPCs) are generated from multiple progenitor domains in the telencephalon in developmental succession from ventral to dorsal. Previous studies showed that Wnt signaling inhibits the differentiation of OPCs into mature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29e703104e1ec59600e9a59952a00b3a
https://doi.org/10.1523/jneurosci.1934-10.2010
https://doi.org/10.1523/jneurosci.1934-10.2010
Autor:
Vladimir V. Rymar, Freda D. Miller, Christine D. Pozniak, Fanie Barnabé-Heider, Anna F. Lee, Abbas F. Sadikot
Publikováno v:
The Journal of Neuroscience. 22:9800-9809
Here, we show that the p53 family member, p73, is necessary for survival and long-term maintenance of CNS neurons, including postnatal cortical neurons. In p73-/- animals, cortical neuron number is normal at birth but decreases significantly by postn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e307df4f5f1c2ca19ad337189be8f95
https://doi.org/10.1523/jneurosci.22-22-09800.2002
https://doi.org/10.1523/jneurosci.22-22-09800.2002
Autor:
Christine D. Pozniak, Marta Majdan, Shernaz X. Bamji, Carrie G. Causing, Daniel J. Belliveau, Judi Kohn, Raquel Aloyz, Freda D. Miller
Publikováno v:
The Journal of Cell Biology
To determine whether the p75 neurotrophin receptor (p75NTR) plays a role in naturally occurring neuronal death, we examined neonatal sympathetic neurons that express both the TrkA tyrosine kinase receptor and p75NTR. When sympathetic neuron survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdcc810cd04a24326fb74baaad252152
https://doi.org/10.1083/jcb.140.4.911
https://doi.org/10.1083/jcb.140.4.911
Autor:
Jasvinder K. Atwal, Christine D. Pozniak, Jean G. Toma, David L. Kaplan, Raquel Aloyz, Freda D. Miller, Shernaz X. Bamji
Publikováno v:
The Journal of Cell Biology
Naturally occurring sympathetic neuron death is the result of two apoptotic signaling events: one normally suppressed by NGF/TrkA survival signals, and a second activated by the p75 neurotrophin receptor. Here we demonstrate that the p53 tumor suppre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae311cac326b06c5800443df8c1a847
http://europepmc.org/articles/PMC2132983
http://europepmc.org/articles/PMC2132983
Autor:
Daniel J. Belliveau, Dmitri A. Rusakov, Freda D. Miller, Irena Krivko, Christine D. Pozniak, Judi Kohn, David L. Kaplan, Christian Lachance
Publikováno v:
The Journal of Cell Biology
In this report we examine the biological and molecular basis of the control of sympathetic neuron differentiation and survival by NGF and neurotrophin-3 (NT-3). NT-3 is as efficient as NGF in mediating neuritogenesis and expression of growth-associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f3a3c13e80ed5c0296f5f29e4de072
https://doi.org/10.1083/jcb.136.2.375
https://doi.org/10.1083/jcb.136.2.375
Autor:
Christine D. Pozniak, Jean G. Toma, Audrey Speelman, James Fabian, Eddie Chang, Freda D. Miller, T.C. Mathew
Publikováno v:
Developmental Biology. 161:206-217
Exposure of neuronal terminals to target-derived NGF has been hypothesized to regulate cell body responses at a distance. To test this hypothesis and, more specifically, to determine whether NGF distally regulates the synthesis of its two characteriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623ffffb25f15dc0b09bf6fc78582b27
https://doi.org/10.1006/dbio.1994.1021
https://doi.org/10.1006/dbio.1994.1021
Publikováno v:
Genome Biology
Quantitative trait locus analysis of two inbred mouse strains has revealed that cell survival is most highly correlated with neurogenesis.
Adult neurogenesis in the hippocampus is under complex genetic control. A recent comparative study of two
Adult neurogenesis in the hippocampus is under complex genetic control. A recent comparative study of two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b8ebf949d09bbc847e40cd022e674a8
https://pubmed.ncbi.nlm.nih.gov/16584531
https://pubmed.ncbi.nlm.nih.gov/16584531
Publikováno v:
Science's STKE. 2006
It is now widely accepted that discrete regions of the adult brain contain stem cells that continue to generate new neurons. However, it remains unclear what molecular signals define the neurogenic niche and how such signals act on the heterogeneous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74a5c323a368c30baabd77d98b0b0be0
https://doi.org/10.1126/stke.3192006pe5
https://doi.org/10.1126/stke.3192006pe5