Výsledky vyhledávání - "Christine Colby"

Comparison of outcomes after transplantation of peripheral blood stem cells versus bone marrow following an identical nonmyeloablative conditioning regimen

Autor: Bimalangshu R. Dey, Eyal C. Attar, Andrew Yee, Steven L. McAfee, Nancy J. Tarbell, Megan Sykes, David H. Sachs, David T. Ting, Juanita Shaffer, Frederic I. Preffer, Christine Colby, Martin Caron, Thomas R. Spitzer, Susan L. Saidman, Karen K. Ballen, Karen A. Power

Publikováno v: Bone Marrow Transplantation. 40:19-27

This is the first study to examine the outcomes in 54 patients with hematologic malignancies who received an HLA-matched related donor bone marrow (BM, n = 42) or GCSF-mobilized peripheral blood stem cells (PBSC, n = 12) following identical nonmyeloa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad991beb34413037521eed02bf184c5c
https://doi.org/10.1038/sj.bmt.1705688

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Stable Multilineage Chimerism without Graft versus Host Disease Following Nonmyeloablative Haploidentical Hematopoietic Cell Transplantation

Autor: Haley Rowland, David M. Neville, Krzysztof J. Wikiel, Thomas R. Spitzer, Andrew M. Cameron, Robert A. Cina, Christene A. Huang, Patricia Lee, Shehan Hettiarachy, Christine Colby, Jennifer Goodrich

Publikováno v: Transplantation. 81:1677-1685

Background Hematopoietic cell transplantation may offer the only cure for patients with hematological diseases. The clinical application of this therapy has been limited by toxic conditioning and lack of matched donors. Haploidentical transplantation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce8764bbbbe93e10ad218f4c275f3f8
https://doi.org/10.1097/01.tp.0000226061.59196.84

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Nonmyeloablative bone marrow transplantation: infectious complications in 65 recipients of HLA-identical and mismatched transplants

Autor: Andrew Daly, David H. Sachs, Beow Y. Yeap, Robert Sackstein, Nancy J. Tarbell, Megan Sykes, B.R. Dey, Christine Colby, Thomas R. Spitzer, Steven L. McAfee, Leah Schulte

Publikováno v: Biology of Blood and Marrow Transplantation. 9:373-382

Infections are a common complication of allogeneic bone marrow transplantation and the leading cause of transplantation-related mortality. It had been hypothesized that transplantation following nonmyeloablative preparative regimens would result in f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23da761827e0277c3c770f41b8cbe51c
https://doi.org/10.1016/s1083-8791(03)00100-9

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Nonmyeloablative haploidentical stem-cell transplantation using anti-CD2 monoclonal antibody (MEDI-507)-based conditioning for refractory hematologic malignancies

Autor: Juanita Shaffer, Megan Sykes, David H. Sachs, Steven L. McAfee, Howard Grossberg, Bimalangshu R. Dey, Thomas R. Spitzer, Stephen I. Alexander, J Hope, Christine Colby, Frederic I. Preffer

Publikováno v: Transplantation. 75:1748-1751

We initiated a clinical trial of nonmyeloablative haploidentical stem-cell transplantation (SCT) using MEDI-507, an immunoglobulin-G1 monoclonal anti-CD2 antibody. The trial was based on a preclinical major histocompatibility complex-mismatched bone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::592441fd8908085dd44fd2653d20bc26
https://doi.org/10.1097/01.tp.0000064211.23536.ad

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Impact of prophylactic donor leukocyte infusions on mixed chimerism, graft-versus-host disease, and antitumor response in patients with advanced hematologic malignancies treated with nonmyeloablative conditioning and allogeneic bone marrow transplantation

Autor: Bimalangshu R. Dey, Steven L. McAfee, Christine Colby, Robert Sackstein, Nancy J. Tarbell, Megan Sykes, Susan L. Saidman, David H. Sachs, Thomas R. Spitzer

Publikováno v: Biology of Blood and Marrow Transplantation. 9(5):320-329

In an attempt to capture graft-versus-tumor effects without graft-versus-host disease (GVHD), the authors initiated a trial of nonmyeloablative allogeneic bone marrow transplantation (BMT) in patients with advanced hematologic malignancies, with the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::548f34c3d9b0e06179609017125024a3

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Induction Of Kidney Allograft Tolerance After Transient Lymphohematopoietic Chimerism In Patients With Multiple Myeloma And End-Stage Renal Disease1

Autor: Megan Sykes, David H. Sachs, Steven L. McAfee, Christine Colby, Thomas R. Spitzer, Susan L. Saidman, Bimalangshu R. Dey, Leo Buhler, Nina Tolkoff-Rubin, Cosimi Ab, Francis L. Delmonico, Robert Sackstein

Publikováno v: Transplantation. 74:1405-1409

Two patients with end-stage renal disease secondary to multiple myelomas were treated with combined kidney and bone marrow transplantation in an effort to achieve donor-specific allotolerance through the induction of mixed lymphohematopoietic chimeri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9eb72e7b750ff95d2482b89d3208bcab
https://doi.org/10.1097/00007890-200211270-00011

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Dose-escalated total body irradiation and autologous stem cell transplantation for refractory hematologic malignancy

Autor: Thomas R. Spitzer, Steven L. McAfee, Simon N. Powell, Christine Colby

Publikováno v: International Journal of Radiation Oncology*Biology*Physics. 53:151-156

Purpose: To evaluate the feasibility of dose escalation of total body irradiation (TBI) above the previously reported maximally tolerated dose, we have undertaken a Phase I–II trial of dose-escalated TBI with autologous peripheral blood stem cell t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a50637f85a02f4941e053fb95e2cab
https://doi.org/10.1016/s0360-3016(02)02743-8

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Fluctuating lymphocyte chimerism, tolerance and anti-tumor response in a patient with refractory lymphoma receiving non-myeloablative conditioning and a haploidentical related allogeneic bone marrow transplant

Autor: Christine Colby, Han Chong Toh, Frederic I. Preffer, Robert Sackstein, Thomas R. Spitzer, Jeffrey S. Clark, Megan Sykes, Susan L. Saidman, David Dombkowski, Steve McAfee, Stephen Alexander

Publikováno v: Cytokines, Cellular & Molecular Therapy. 7:43-47

A 51-year-old patient with refractory non-Hodgkin lymphoma (NHL) received non-myeloablative conditioning and a two of six (A, B, DR) human leucocyte antigen (HLA) mismatched donor BMT. Post-BMT lymphocytes showed fluctuating T- and natural killer (NK

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2885276c04f0f0e031f8789327fa200
https://doi.org/10.1080/13684730412331302054

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Successful allogeneic stem cell transplantation with nonmyeloablative conditioning in patients with relapsed hematologic malignancy following autologous stem cell transplantation

Autor: David H. Sachs, Cathleen Poliquin, Dina Weymouth, Christine Colby, Megan Sykes, Steven L. McAfee, Thomas R. Spitzer, Julie Vanderklish, Bimalangshu R. Dey, Susan L. Saidman, Robert Sackstein

Publikováno v: Biology of Blood and Marrow Transplantation. 7(11):604-612

The use of myeloablative preparative therapy and allogeneic stem cell transplantation (alloSCT) as salvage therapy for adult patients with relapsed hematologic malignancy after autologous stem cell transplantation (autoSCT) is generally unsuccessful

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83b020f532c9705dd152929af09333dd

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