Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Christine C. Helms"'
Autor:
Manasa Rajeev, Christine C. Helms
Publikováno v:
Polymers, Vol 15, Iss 23, p 4555 (2023)
Electrospun fibers range in size from nanometers to micrometers and have a multitude of potential applications that depend upon their morphology and mechanics. In this paper, we investigate the effect of polymer solution entanglement on the mechanica
Externí odkaz:
https://doaj.org/article/4f85ab0dc76b40c2a6e252f85342aef4
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Erythrocytes regulate vascular function through the modulation of oxygen delivery and the scavenging and generation of nitric oxide (NO). First, hemoglobin inside the red blood cell binds oxygen in the lungs and delivers it to tissues throughout the
Externí odkaz:
https://doaj.org/article/2e8222995955461aa5fb4faea163d2e4
Autor:
Najnin Rimi, Christine C. Helms
BackgroundFluorescent beads are often used as a tool for visualizing fibrin fibers and can mimic the size of microparticles in the blood. Studies showed microparticles alter the appearance and behavior of whole blood clot systems.ObjectivesHere we in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cf25feede63f11ec1bfbafa94e00fbe
https://doi.org/10.1101/2021.09.22.461388
https://doi.org/10.1101/2021.09.22.461388
Autor:
Mary T Kinney, Marlien Pieters, Stephen R. Baker, Roger Cubcciotti, Justin Sigley, Peter H. Brubaker, Martin Guthold, Christine C. Helms, Wei Li
Publikováno v:
BioMed Research International, Vol 2017 (2017)
BioMed Research International
BioMed Research International
The major structural component of a blood clot is a meshwork of fibrin fibers. It has long been thought that the internal structure of fibrin fibers is homogeneous; that is, the protein density and the bond density between protofibrils are uniform an
Publikováno v:
Biological Chemistry. 398:319-329
Nitrite was once thought to be inert in human physiology. However, research over the past few decades has established a link between nitrite and the production of nitric oxide (NO) that is potentiated under hypoxic and acidic conditions. Under this n
Autor:
John W. Weisel, Marlien Pieters, Martin Guthold, Chandrasekaran Nagaswami, Christine C. Helms, Wei Li, Justin Sigley
Publikováno v:
Biophysical Journal. 110:1400-1410
The major structural component of a blood clot is a mesh of fibrin fibers. Our goal was to determine whether fibrinogen glycation and fibrin fiber diameter have an effect on the mechanical properties of single fibrin fibers. We used a combined atomic
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 9 (2018)
Frontiers in Physiology, Vol 9 (2018)
Erythrocytes regulate vascular function through the modulation of oxygen delivery and the scavenging and generation of nitric oxide (NO). First, hemoglobin inside the red blood cell binds oxygen in the lungs and delivers it to tissues throughout the
Autor:
Christian Keggi, John Janes, Chen Liu, Christine C. Helms, Nadeem Wajih, David L. Caudell, Daniel B. Kim-Shapiro, Amber N. Lee, Mark T. Gladwin, Jun Wang, Madison Marvel, Andrea Belanger, Swati Basu, Debra I. Diz, Xiaohua Liu, Paul J. Laurienti
Publikováno v:
Journal of Biological Chemistry. 290:1281-1294
Nitrite signaling likely occurs through its reduction to nitric oxide (NO). Several reports support a role of erythrocytes and hemoglobin in nitrite reduction, but this remains controversial, and alternative reductive pathways have been proposed. In
Autor:
Kenneth E. Remy, Junfeng Sun, Harvey G. Klein, Mark T. Gladwin, Tamir Kanias, Meghna Alimchandani, Daniel B. Kim-Shapiro, Irene Cortés-Puch, Dong Wang, Jing Feng, Martha Quezado, Christine C. Helms, Steven B. Solomon, Charles Natanson, Andreas Perlegas
Publikováno v:
Transfusion. 54:1712-1724
Background In experimental pneumonia we found that transfused older blood increased mortality and lung injury that was associated with increased in vivo hemolysis and elevated plasma cell-free hemoglobin (CFH), non–transferrin-bound iron (NTBI), an
Autor:
Anne Caroline Gilmore, Christine C. Helms, Shannon Kapadia, Daniel B. Kim-Shapiro, Zhexi Lu, Swati Basu
Publikováno v:
Blood coagulationfibrinolysis : an international journal in haemostasis and thrombosis. 28(5)
Fibrin fibers form the structural backbone of blood clots. The structural properties of fibrin clots are highly dependent on formation kinetics. Environmental factors such as protein concentration, pH, salt, and protein modification, to name a few, c