Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Christine C. Gispen"'
Autor:
Rosemarie D. L. C. Bernabe, Ghislaine J. M. W. van Thiel, Nancy S. Breekveldt, Christine C. Gispen, Johannes J. M. van Delden
Publikováno v:
BMC Medical Ethics, Vol 21, Iss 1, Pp 1-8 (2020)
Abstract Background In the EU, clinical assessors, rapporteurs and the Committee for Medicinal Products for Human Use are obliged to assess the ethical aspects of a clinical development program and include major ethical flaws in the marketing authori
Externí odkaz:
https://doaj.org/article/39b586aa966944d7bde67fb0fc8bd504
Autor:
Marieke J. H. J. Dekker, Sieta T. de Vries, Carolien H. M. Versantvoort, Ellen G. E. Drost-van Velze, Mansi Bhatt, Peter J. K. van Meer, Ineke K. Havinga, Christine C. Gispen-de Wied, Peter G. M. Mol
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
This study assessed to what extent women were included in all phases of drug development; whether the clinical studies in the marketing authorization application dossiers include information per sex; and explored whether there are differences between
Externí odkaz:
https://doaj.org/article/a5e7cdfb136d43a79f4ae6dc16dd8b7c
Autor:
Yvonne Schuller, Marieke Biegstraaten, Carla E. M. Hollak, Heinz-Josef Klümpen, Christine C. Gispen-de Wied, Violeta Stoyanova-Beninska
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 13, Iss 1, Pp 1-11 (2018)
Abstract Background Evaluation of evidence for efficacy of orphan medicinal products (OMPs) for rare malignancies may be hampered by the use of tumor measurements instead of clinical endpoints. This may cause efficacy data to not always match effecti
Externí odkaz:
https://doaj.org/article/54c1406d95344772a624b2f11cf50998
Autor:
Marieke J. H. J. Dekker, Jacoline C. Bouvy, Diana O'Rourke, Robin Thompson, Amr Makady, Pall Jonsson, Christine C. Gispen-de Wied
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Aims: To facilitate regulatory learning, we evaluated similarities and differences in evidence requirements between regulatory and health technology assessment (HTA) bodies of Alzheimer's disease (AD) approved products.Methods: The European marketing
Externí odkaz:
https://doaj.org/article/ddb542f1dac448c5b5ebf4e76cca4fb4
Autor:
Guilherme S Ferreira, Désirée H Veening-Griffioen, Wouter P C Boon, Ellen H M Moors, Christine C Gispen-de Wied, Huub Schellekens, Peter J K van Meer
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218014 (2019)
IntroductionPoor translation of efficacy data derived from animal models can lead to clinical trials unlikely to benefit patients-or even put them at risk-and is a potential contributor to costly and unnecessary attrition in drug development.Objectiv
Externí odkaz:
https://doaj.org/article/0f14ca084e9b487cb8a1f7e01b4a38f6
Autor:
Guilherme S Ferreira, Désirée H Veening-Griffioen, Wouter P C Boon, Ellen H M Moors, Christine C Gispen-de Wied, Huub Schellekens, Peter J K van Meer
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0220325 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0218014.].
Externí odkaz:
https://doaj.org/article/4a9a1b7212f24fd09f77e8357dbb8bd4
Akademický článek
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Autor:
Bram W.C. Storosum, Taina Mattila, Tamar D. Wohlfarth, Christine C. Gispen-de Wied, Kit C.B. Roes, Wim van den Brink, Lieuwe de Haan, Damiaan A.J.P. Denys, Jasper B. Zantvoord
Publikováno v:
Psychiatry research, 320. Elsevier Ireland Ltd
Psychiatry Research, 320
Psychiatry research, 320:114997. Elsevier Ireland Ltd
Psychiatry Research, 320
Psychiatry research, 320:114997. Elsevier Ireland Ltd
Contains fulltext : 291389.pdf (Publisher’s version ) (Open Access) OBJECTIVE: To determine whether gender and menopausal status moderate the response to antipsychotic medication in patients with schizophrenia. METHODS: We analyzed data of 22 short
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b9e87144925089575d8f46721c207bb
https://pure.knaw.nl/portal/en/publications/a58eae0c-484c-4225-9cc3-2785050a4d15
https://pure.knaw.nl/portal/en/publications/a58eae0c-484c-4225-9cc3-2785050a4d15
Autor:
Doerine J. Postma, Peter A. G. M. De Smet, Christine C. Gispen-de Wied, Hubert G. M. Leufkens, Aukje K. Mantel-Teeuwisse
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Background: Drug shortages are a potential threat to public health. Reliable data on drug shortages is limited. The objective was to examine the extent and nature of potential drug shortages signaled by authorities and pharmacy practice in the Nether
Externí odkaz:
https://doaj.org/article/7460d039dbe54308acff4a90ab8f48b1
Autor:
Schilder, Isabel PA, Veening-Griffioen, Désirée H, Ferreira, Guilherme S, Meer, Peter JK Van, Wied, Christine C Gispen-de, Schellekens, Huub, Boon, Wouter PC, Moors, Ellen HM, Afd Pharmaceutics, Innovation and Sustainability, Innovation Studies, Pharmaceutics
Publikováno v:
Journal of Scientometric Research, 9(3), 277
Investments in drug development for Alzheimer's disease (AD) have not led to the availability of a treatment to cure or halt the progression of the disease. This study aimed to provide insights into the current lack of an effective therapy against AD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a31c1540990ebd5466dc3f18ff5ebd14
https://doi.org/10.5530/jscires.9.3.35
https://doi.org/10.5530/jscires.9.3.35