Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Christine Babiuk"'
Publikováno v:
Journal of Pharmacokinetics and Biopharmaceutics. 21:323-334
Five major objectives for pharmacokinetic investigations in support of toxicity studies are identified as follows: Assess whether animals exhibited measurable blood concentrations in a dose-dependent manner; estimate average area under the concentrat
Publikováno v:
Toxicology and applied pharmacology. 102(1)
Thiol-containing antibotes for acute acrylonitrile (AN) toxicity may exert their action by chemically reacting with AN, by replacing critical sulfhydryl groups cyanoethylated by AN, and by detoxifying cyanide produced from AN metabolism. We have eval
Publikováno v:
Journal of Toxicology and Environmental Health. 23:425-430
Publikováno v:
Drug metabolism reviews. 20(2-4)
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 9(4)
Ethylenediamine (EDA) is reported to be a poorly characterized iatrogenic and occupational contact sensitizer. To better characterize EDA hypersensitivity, a guinea pig model was employed in which the animals were exposed epicutaneously to simulate c
Publikováno v:
Scopus-Elsevier
We have utilised several inhibitors to assess the effects of kininases on the contractile activity of bradykinin (BK), kallidin (KD), des-Arg 9 -BK and des-Arg 10 -KD on two isolated blood vessels, the rabbit aorta and mesenteric vein. The responses
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