Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Christine B. Karim"'
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract We have used electron paramagnetic resonance, with rigid and stereospecific spin labels, to resolve structural states in calmodulin (CaM), as affected by binding of Ca and a CaM-binding peptide (RyRp) derived from the ryanodine receptor (RyR
Externí odkaz:
https://doaj.org/article/e18d0469e22a4eb1a83261faac5a55bf
Autor:
Joseph M. Autry, Christine B. Karim, Sudeep Perumbakkam, Carrie J. Finno, Erica C. McKenzie, David D. Thomas, Stephanie J. Valberg
Publikováno v:
Veterinary Sciences, Vol 7, Iss 4, p 178 (2020)
Ca2+ regulation in equine muscle is important for horse performance, yet little is known about this species-specific regulation. We reported recently that horse encode unique gene and protein sequences for the sarcoplasmic reticulum (SR) Ca2+-transpo
Externí odkaz:
https://doaj.org/article/5f86453efed643e3abdc5893db7081d8
Autor:
Anthony R. Braun, Andrew K. Lewis, Christine B. Karim, Stephen L. Peery, Benjamin E. Brummel, Jonathan N. Sachs, Christopher C. Valley
Publikováno v:
Journal of Molecular Biology. 428:4843-4855
Death receptor 5 (DR5) is an apoptosis-inducing member of the tumor necrosis factor receptor superfamily, whose activity has been linked to membrane cholesterol content. Upon ligand binding, DR5 forms large clusters within the plasma membrane that ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5b74098e1fb249e0641e7f4fbe2d63
https://doi.org/10.1016/j.jmb.2016.10.001
https://doi.org/10.1016/j.jmb.2016.10.001
Autor:
Joseph M. Autry, Bengt Svensson, Samuel F. Carlson, Zhenhui Chen, Sudeep Perumbakkam, Stephanie J. Valberg, Carrie J. Finno, Cocco M, David D. Thomas, Christine B. Karim, L. M. Espinoza-Fonseca
We have analyzed gene transcription, protein expression, and enzymatic activity of the Ca2+-transporting ATPase (SERCA) in horse gluteal muscle. Horses are bred for peak athletic performance but exhibit a high incidence of exertional rhabdomyolysis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f187fbcd2655f618ffc5c5e9ceca6ffb
Autor:
Christine B. Karim, Joseph M. Autry, David D. Thomas, Mariana Cocco, Stephanie J. Valberg, Samuel F. Carlson
Publikováno v:
Anal Biochem
We have analyzed protein expression and enzyme activity of the sarcoplasmic reticulum Ca2+-transporting ATPase (SERCA) in horse gluteal muscle. Horses exhibit a high incidence of recurrent exertional rhabdomyolysis, with myosolic Ca2+ proposed, but y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1696b9519329d0ed34cae7b9a22c063d
https://doi.org/10.1016/j.ab.2020.113965
https://doi.org/10.1016/j.ab.2020.113965
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
We have used electron paramagnetic resonance, with rigid and stereospecific spin labels, to resolve structural states in calmodulin (CaM), as affected by binding of Ca and a CaM-binding peptide (RyRp) derived from the ryanodine receptor (RyR), the Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758ed9ac2ca670499be8f58ba053d776
http://europepmc.org/articles/PMC6048129
http://europepmc.org/articles/PMC6048129
Publikováno v:
Biophysical Journal. 116:284a-285a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76399e6f088dc6ce9b2457a43abf8d49
https://doi.org/10.1016/j.bpj.2018.11.1539
https://doi.org/10.1016/j.bpj.2018.11.1539
Autor:
Stephanie J. Valberg, Bengt Svensson, Carrie J. Finno, Joseph M. Autry, Zhenhui Chen, Christine B. Karim, David D. Thomas, Sudeep Perumbakkam
Publikováno v:
Biophysical Journal. 116:238a-239a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af70268cb28480a422153b800b2c57c6
https://doi.org/10.1016/j.bpj.2018.11.1309
https://doi.org/10.1016/j.bpj.2018.11.1309
Publikováno v:
Biophysical Journal. 114:159a-160a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6eac5259aa443f1368c48b53d92fdab4
https://doi.org/10.1016/j.bpj.2017.11.893
https://doi.org/10.1016/j.bpj.2017.11.893
Publikováno v:
Biophysical Journal. 110(3)
We have used site-directed spin labeling and double electron-electron resonance spectroscopy (DEER) to probe the structural dynamics of calmodulin in the context of regulating the skeletal muscle Ca release channel, the ryanodine receptor (RyR1). Con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bdf78b523c06b0dc82c544a392d2098