Zobrazeno 1 - 10
of 672
pro vyhledávání: '"Christine B, Ambrosone"'
Autor:
Angela R. Omilian, Rikki Cannioto, Lucas Mendicino, Leighton Stein, Wiam Bshara, Bo Qin, Elisa V. Bandera, Nur Zeinomar, Scott I. Abrams, Chi-Chen Hong, Song Yao, Thaer Khoury, Christine B. Ambrosone
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-12 (2024)
Abstract Background Tumor-associated macrophages (TAMs) are a prominent immune subpopulation in the tumor microenvironment that could potentially serve as therapeutic targets for breast cancer. Thus, it is important to characterize this cell populati
Externí odkaz:
https://doaj.org/article/6f527a7fa43b4abe837920ef9add5330
Autor:
Christine Hook, Udit Chatterjee, Haiyang Sheng, Qianqian Zhu, Timothy Robinson, Janise M. Roh, Cecile A. Laurent, Catherine Lee, Jennifer Delmerico, Joan C. Lo, Christine B. Ambrosone, Lawrence H. Kushi, Marilyn L. Kwan, Song Yao
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-7 (2024)
Abstract Identifying women at high risk of osteoporotic fracture from aromatase inhibitor (AI) therapy for breast cancer is largely based on known risk factors for healthy postmenopausal women, which might not accurately reflect the risk in breast ca
Externí odkaz:
https://doaj.org/article/4b4e10f7d40b4f7899ffd2f7f1dff95a
Autor:
Yiwey Shieh, Jacquelyn Roger, Christina Yau, Denise M. Wolf, Gillian L. Hirst, Lamorna Brown Swigart, Scott Huntsman, Donglei Hu, Jovia L. Nierenberg, Pooja Middha, Rachel S. Heise, Yushu Shi, Linda Kachuri, Qianqian Zhu, Song Yao, Christine B. Ambrosone, Marilyn L. Kwan, Bette J. Caan, John S. Witte, Lawrence H. Kushi, Laura van ‘T Veer, Laura J. Esserman, Elad Ziv
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-11 (2023)
Abstract Aggressive breast cancers portend a poor prognosis, but current polygenic risk scores (PRSs) for breast cancer do not reliably predict aggressive cancers. Aggressiveness can be effectively recapitulated using tumor gene expression profiling.
Externí odkaz:
https://doaj.org/article/138d8faa316e4fb8af5632688f767d95
Autor:
Song Yao, Shipra Gandhi, Christine B Ambrosone, Warren Davis, Eva Culakova, Guilherme Cantuaria, Lori Sakoda, Igor PuzanovCI, Michelle Janelsins, Thaer Khoury, Elisa Rodriguez, Allison Magnuson, Jennifer M Suga, Rajasree P Chowdry, Lawrence H Kushi, Karen Mustian, Gary R Morrow, Charles Kamen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/fbc6be5bb2b849b5be946d1a17fe9b4c
Autor:
Jianhong Chen, Mark D. Long, Sirinapa Sribenja, Sung Jun Ma, Li Yan, Qiang Hu, Song Liu, Thaer Khoury, Chi-Chen Hong, Elisa Bandera, Anurag K. Singh, Elizabeth A. Repasky, Elizabeth G. Bouchard, Michael Higgins, Christine B. Ambrosone, Song Yao
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-10 (2023)
Abstract Background Disadvantaged socioeconomic position (SEP), including lower educational attainment and household income, may influence cancer risk and outcomes. We hypothesized that DNA methylation could function as an intermediary epigenetic mec
Externí odkaz:
https://doaj.org/article/f1076641aa4049a1a139134b19728f57
Autor:
Rochelle Payne Ondracek, Jianhong Chen, Beth Marosy, Sirinapa Szewczyk, Leonard Medico, Amrutha Sherly Mohan, Priya Nair, Rachel Pratt, Janise M. Roh, Thaer Khoury, John Carpten, Lawrence H. Kushi, Julie R. Palmer, Kim Doheny, Warren Davis, Michael J. Higgins, Song Yao, Christine B. Ambrosone
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-10 (2022)
Abstract Background The use of archived formalin-fixed paraffin-embedded (FFPE) tumor tissues has become a common practice in clinical and epidemiologic genetic research. Simultaneous extraction of DNA and RNA from FFPE tissues is appealing but can b
Externí odkaz:
https://doaj.org/article/897299b8de694412bd623262562fbce6
Autor:
Jianhong Chen, Michael J. Higgins, Qiang Hu, Thaer Khoury, Song Liu, Christine B. Ambrosone, Zhihong Gong
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionIncidence of estrogen receptor (ER)-negative breast cancer, an aggressive tumor subtype associated with worse prognosis, is higher among African American/Black women than other US racial and ethnic groups. The reasons for this disparity r
Externí odkaz:
https://doaj.org/article/1ee7428404bd4b3ca385a79c10e729c8
Autor:
Mmadili N. Ilozumba, Song Yao, Adana A. M. Llanos, Angela R. Omilian, Weizhou Zhang, Susmita Datta, Chi-Chen Hong, Warren Davis, Thaer Khoury, Elisa V. Bandera, Michael Higgins, Christine B. Ambrosone, Ting-Yuan David Cheng
Publikováno v:
Discover Oncology, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Background Aberrant activation of the mammalian Target of Rapamycin (mTOR) pathway has been linked to obesity and endocrine therapy resistance, factors that may contribute to Black-White disparities in breast cancer outcomes. We evaluated as
Externí odkaz:
https://doaj.org/article/aa74f73f590449e0b3b90be0c1d170ee
Autor:
Angela R. Omilian, Haiyang Sheng, Chi‐Chen Hong, Elisa V. Bandera, Thaer Khoury, Christine B. Ambrosone, Song Yao
Publikováno v:
Molecular Oncology, Vol 16, Iss 1, Pp 54-68 (2022)
The NanoString GeoMx digital spatial profiling is a new multiplexed platform that quantifies the abundance of tumor‐ and immune‐related proteins in a spatially resolved manner. We performed DSP for the simultaneous assessment of 52 analytes withi
Externí odkaz:
https://doaj.org/article/428d4e276c9f4cafb6ba75ebac302684
Autor:
Ting-Yuan David Cheng, Angela R. Omilian, Song Yao, Weizhou Zhang, Susmita Datta, Wiam Bshara, Rochelle Payne Ondracek, Warren Davis, Song Liu, Chi-Chen Hong, Elisa V. Bandera, Thaer Khoury, Christine B. Ambrosone
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-11 (2021)
Abstract Background The mechanistic target of rapamycin (mTOR) pathway promoted by positive energy imbalance and insulin-like growth factors can be a mechanism by which obesity influences breast cancer risk. We evaluated the associations of body fatn
Externí odkaz:
https://doaj.org/article/998df8435a9742a3bb4e7e2d04cc07c9