Effect of the Size and Shape of Dendronized Iron Oxide Nanoparticles Bearing a Targeting Ligand on MRI, Magnetic Hyperthermia, and Photothermia Properties—From Suspension to In Vitro Studies

Autor: Barbara Freis, Maria De Los Angeles Ramirez, Céline Kiefer, Sébastien Harlepp, Cristian Iacovita, Céline Henoumont, Christine Affolter-Zbaraszczuk, Florent Meyer, Damien Mertz, Anne Boos, Mariana Tasso, Sonia Furgiuele, Fabrice Journe, Sven Saussez, Sylvie Bégin-Colin, Sophie Laurent

Publikováno v: Pharmaceutics, Vol 15, Iss 4, p 1104 (2023)

Functionalized iron oxide nanoparticles (IONPs) are increasingly being designed as a theranostic nanoplatform combining specific targeting, diagnosis by magnetic resonance imaging (MRI), and multimodal therapy by hyperthermia. The effect of the size

Externí odkaz: https://doaj.org/article/c8813de97f92465fa5097daccaf0465e

Impacts of Resveratrol and Pyrogallol on Physicochemical, Mechanical and Biological Properties of Epoxy-Resin Sealers

Autor: Naji Kharouf, Salvatore Sauro, Louis Hardan, Amr Fawzi, Ilona Eveline Suhanda, Jihed Zghal, Frédéric Addiego, Christine Affolter-Zbaraszczuk, Youri Arntz, Vincent Ball, Florent Meyer, Youssef Haikel, Davide Mancino

Publikováno v: Bioengineering, Vol 9, Iss 3, p 85 (2022)

This study aimed at evaluating the physicochemical and biological properties of experimental epoxy-resin sealers containing polyphenols such as resveratrol and pyrogallol. A conventional epoxy resin (OB) was modified by adding different concentration

Externí odkaz: https://doaj.org/article/3022076a6655480195438bc872171a44

How a grafting anchor tailors the cellular uptake and in vivo fate of dendronized iron oxide nanoparticles

Autor: Delphine Felder-Flesch, Sébastien Boutry, Catalina Bordeianu, Sylvie Begin-Colin, Sophie Laurent, Florent Meyer, Robert N. Muller, Christine Affolter-Zbaraszczuk, Audrey Parat

Publikováno v: Journal of materials chemistry‎ B
Journal of materials chemistry‎ B, Royal Society of Chemistry, 2017, 5 (26), pp.5152-5164. ⟨10.1039/c7tb00781g⟩

Superparamagnetic spherical iron oxide nanoparticles of 10 nm diameter have been synthesized by thermal decomposition and grafted through a direct ligand exchange protocol with two dendrons bearing respectively a monophosphonic anchor (D2) or a bipho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18117a06778e7454f9817d11999b329a
https://hal.archives-ouvertes.fr/hal-03433759

Design of hybrid protein-coated magnetic core-mesoporous silica shell nanocomposites for MRI and drug release assessed in a 3D tumor cell model

Autor: Morgane Rabineau, Paula Duenas Ramirez, Sylvie Begin-Colin, Christine Affolter-Zbaraszczuk, Mathilde Ménard, Damien Mertz, Florent Meyer, Alexandre Adam

Publikováno v: Nanotechnology
Nanotechnology, Institute of Physics, 2019, 30 (17), pp.174001. ⟨10.1088/1361-6528/aafe1c⟩
Nanotechnology, 2019, 30 (17), pp.174001. ⟨10.1088/1361-6528/aafe1c⟩

International audience; In this work, we describe the design and the use of a novel theranostic hybrid nanocomposite made of an iron oxide core and a mesoporous silica shell (IO@MS) of ca. 30 nm coated by human serum albumin (HSA) layer for magnetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::029e9906083d267e7d6ecd0d22d89988
https://doi.org/10.1088/1361-6528/aafe1c

Composite vector formulation for multiple siRNA delivery as a host targeting antiviral in a cell culture model of hepatitis C virus (HCV) infection

Autor: Emilie Crouchet, Joelle Ogier, Thomas F. Baumert, Florent Meyer, Catherine Schuster, R. Saad, Christine Affolter-Zbaraszczuk

Publikováno v: Journal of Materials Chemistry B
Journal of materials chemistry‎ B
Journal of materials chemistry‎ B, Royal Society of Chemistry, 2017, 5 (4), pp.858-865. ⟨10.1039/C6TB01718E⟩

International audience; Hepatitis C virus (HCV) infection is a major cause of chronic liver disease and cancer worldwide. RNA interference (RNAi)-based gene therapies have emerged recently as a promising tool to treat chronic viral infections. Indeed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c568a28fc2f7825f5ed5762d9ee6c8