Výsledky vyhledávání - "Christine Addy"

Akademický článek

The structure of SeviL, a GM1b/asialo-GM1 binding R-type lectin from the mussel Mytilisepta virgata

Autor: Kenichi Kamata, Kenji Mizutani, Katsuya Takahashi, Roberta Marchetti, Alba Silipo, Christine Addy, Sam-Yong Park, Yuki Fujii, Hideaki Fujita, Tsuyoshi Konuma, Takahisa Ikegami, Yasuhiro Ozeki, Jeremy R. H. Tame

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)

Abstract SeviL is a recently isolated lectin found to bind to the linear saccharides of the ganglioside GM1b (Neu5Ac $$\alpha$$ α (2-3)Gal $$\beta$$ β (1-3)GalNAc $$\beta$$ β (1-4)Gal $$\beta$$ β (1-4)Glc) and its precursor, asialo-GM1 (Gal $$\be

Externí odkaz: https://doaj.org/article/b60abb2e47eb4f1aadf04cd6577a2ac0

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Computational design of symmetrical eight-bladed β-propeller proteins

Autor: Hiroki Noguchi, Christine Addy, David Simoncini, Staf Wouters, Bram Mylemans, Luc Van Meervelt, Thomas Schiex, Kam Y. J. Zhang, Jeremy R. H. Tame, Arnout R. D. Voet

Publikováno v: IUCrJ, Vol 6, Iss 1, Pp 46-55 (2019)

β-Propeller proteins form one of the largest families of protein structures, with a pseudo-symmetrical fold made up of subdomains called blades. They are not only abundant but are also involved in a wide variety of cellular processes, often by actin

Externí odkaz: https://doaj.org/article/0cc44b94496f4d45a457d731be7329c6

Zobrazit plný text záznamu

Akademický článek

Molecular assemblies built with the artificial protein Pizza

Autor: Jeroen P.M. Vrancken, Jana Aupič, Christine Addy, Roman Jerala, Jeremy R.H. Tame, Arnout R.D. Voet

Publikováno v: Journal of Structural Biology: X, Vol 4, Iss , Pp 100027- (2020)

Recently an artificial protein named Pizza6 was reported, which possesses six identical tandem repeats and adopts a monomeric β-propeller fold with sixfold structural symmetry. Pizza2, a truncated form that consists of a double tandem repeat, self-a

Externí odkaz: https://doaj.org/article/c958711a9c04422ca68e0077fbac0066

Zobrazit plný text záznamu

Akademický článek

Computational design of a symmetrical β-trefoil lectin with cancer cell binding activity

Autor: Daiki Terada, Arnout R. D. Voet, Hiroki Noguchi, Kenichi Kamata, Mio Ohki, Christine Addy, Yuki Fujii, Daiki Yamamoto, Yasuhiro Ozeki, Jeremy R. H. Tame, Kam Y. J. Zhang

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)

Abstract Computational protein design has advanced very rapidly over the last decade, but there remain few examples of artificial proteins with direct medical applications. This study describes a new artificial β-trefoil lectin that recognises Burki

Externí odkaz: https://doaj.org/article/a440be7c963c4aa4b4ba9fc614b1d221

Zobrazit plný text záznamu

Plný text ve formátu HTML

Computational design of symmetrical eight-bladed beta-propeller proteins

Autor: Hiroki Noguchi, Christine Addy, David Simoncini, Staf Wouters, Bram Mylemans, Luc Van Meervelt, Thomas Schiex, Kam Y. J. Zhang, Jeremy R. H. Tame, Arnout R. D. Voet

Publikováno v: IUCRJ
IUCrJ = International Union of Crystallography journal
IUCrJ = International Union of Crystallography journal, International Union of Crystallography 2019, 6 (1), pp.46-55. ⟨10.1107/S205225251801480X⟩
International Union of Crystallography journal
International Union of Crystallography journal, 2019, 6 (1), pp.46-55. ⟨10.1107/S205225251801480X⟩
IUCrJ 1 (6), 46-55. (2019)
International Union of Crystallography journal, International Union of Crystallography 2019, 6 (1), pp.46-55. ⟨10.1107/S205225251801480X⟩
IUCrJ
IUCrJ, Vol 6, Iss 1, Pp 46-55 (2019)

Two artificial β-propeller proteins with eight identical blades were designed, purified and crystallized. X-ray crystallography confirmed the perfectly symmetrical structures of these highly stable proteins.
β-Propeller proteins form one of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0954fdc23752d7e45b346ffae584fe

Zobrazit plný text záznamu

Crystallization of full-length CysB ofKlebsiella aerogenes, a LysR-type transcriptional regulator

Autor: Koen H.G. Verschueren, Eleanor J. Dodson, Christine Addy, Anthony J. Wilkinson

Publikováno v: Acta Crystallographica Section D Biological Crystallography. 57:260-262

CysB is a positive regulator of transcription of genes involved in cysteine biosynthesis in Gram-negative bacteria and belongs to the large family of LysR-type transcriptional regulators. The full-length protein from Klebsiella aerogenes has been cry

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bbfcd3e7c98887b52b6c6d38810fc36
https://doi.org/10.1107/s0907444900016851

Zobrazit plný text záznamu

Akademický článek

Computational design of a self-assembling symmetrical β-propeller protein.

Autor: Voet, Arnout R. D., Hiroki Noguchi, Christine Addy, David Simoncini, Daiki Terada, Satoru Unzai, Sam-Yong Park, Zhang, Kam Y. J., Tame, Jeremy R. H.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America; 10/21/2014, Vol. 111 Issue 42, p15102-15107, 6p

Zobrazit plný text záznamu

The structure of the cofactor-binding fragment of the LysR family member, CysB: a familiar fold with a surprising subunit arrangement

Autor: Garib N. Murshudov, Eleanor J. Dodson, Anthony J. Wilkinson, Richard Tyrrell, Koen H.G. Verschueren, Christine Addy

Publikováno v: Structure. (8):1017-1032

Background: CysB is a tetrameric protein of identical subunits (M r = 36,000) which controls the expression of genes associated with the biosynthesis of cysteine in bacteria. CysB is both an activator and a repressor of transcription whose activity i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98af0b517becaf662ca15da4220dee7d

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání