Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Christine A. Vaine"'
Autor:
Tiziana Petrozziello, Alexandra N. Mills, Christine A. Vaine, Ellen B. Penney, Cara Fernandez-Cerado, Gierold Paul A. Legarda, M. Salvie Velasco-Andrada, Patrick J. Acuña, Mark A. Ang, Edwin L. Muñoz, Cid Czarina E. Diesta, Regina Macalintal-Canlas, Geraldine Acuña-Sunshine, Laurie J. Ozelius, Nutan Sharma, D. Cristopher Bragg, Ghazaleh Sadri-Vakili
Publikováno v:
Neurobiology of Disease, Vol 144, Iss , Pp 105032- (2020)
Neuroinflammation plays a pathogenic role in neurodegenerative diseases and recent findings suggest that it may also be involved in X-linked Dystonia-Parkinsonism (XDP) pathogenesis. Previously, fibroblasts and neuronal stem cells derived from XDP pa
Externí odkaz:
https://doaj.org/article/15954d0e1c254d9e9fe8a45467887824
Autor:
Christine A. Vaine, David Shin, Christina Liu, William T. Hendriks, Jyotsna Dhakal, Kyle Shin, Nutan Sharma, D. Cristopher Bragg
Publikováno v:
Neurobiology of Disease, Vol 100, Iss , Pp 108-118 (2017)
X-linked Dystonia-Parkinsonism (XDP) is a progressive neurodegenerative disease involving the loss of medium spiny neurons within the striatum. An XDP-specific haplotype has been identified, consisting of seven sequence variants which cluster around
Externí odkaz:
https://doaj.org/article/febae821000545189e4c0fe869e984d3
Autor:
Naoto Ito, William T. Hendriks, Jyotsna Dhakal, Christine A. Vaine, Christina Liu, David Shin, Kyle Shin, Noriko Wakabayashi-Ito, Marisela Dy, Trisha Multhaupt-Buell, Nutan Sharma, Xandra O. Breakefield, D. Cristopher Bragg
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 4, Pp 451-462 (2016)
X-linked dystonia-parkinsonism (XDP) is a hereditary neurodegenerative disorder involving a progressive loss of striatal medium spiny neurons. The mechanisms underlying neurodegeneration are not known, in part because there have been few cellular mod
Externí odkaz:
https://doaj.org/article/b20ed9bd4a20450ea8d555d3d5d51d53
Autor:
Nutan Sharma, Cid Czarina E. Diesta, D. Cristopher Bragg, Gierold Paul A. Legarda, Tiziana Petrozziello, Ellen B. Penney, Christine A. Vaine, Ghazaleh Sadri-Vakili, Edwin L. Muñoz, Regina Macalintal-Canlas, Laurie J. Ozelius, Cara Fernandez-Cerado, Alexandra N. Mills, Mark A. Ang, M. Salvie Velasco-Andrada, Patrick J. Acuña, Geraldine Acuña-Sunshine
Publikováno v:
Neurobiology of Disease, Vol 144, Iss, Pp 105032-(2020)
Neuroinflammation plays a pathogenic role in neurodegenerative diseases and recent findings suggest that it may also be involved in X-linked Dystonia-Parkinsonism (XDP) pathogenesis. Previously, fibroblasts and neuronal stem cells derived from XDP pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::009182880af6f2c5f987719acf027771
http://www.sciencedirect.com/science/article/pii/S0969996120303077
http://www.sciencedirect.com/science/article/pii/S0969996120303077
Autor:
Laurie J. Ozelius, Kelly E. Glajch, D. Cristopher Bragg, Geraldine Acuña, Edwin L. Muñoz, Regina Macalintal-Canlas, Christine A. Vaine, Naoto Ito, Nutan Sharma, Gierold Paul A. Legarda, Tiziana Petrozziello, Mark A. Ang, M. Salvie Velasco-Andrada, Ghazaleh Sadri-Vakili, Patrick J. Acuña, Cara Fernandez-Cerado, Alexandra N. Mills, Cid Czarina E. Diesta, William T. Hendriks, Kaly A. Mueller, Ellen B. Penney, Amanda M. Dios, Kotchaphorn Mangkalaphiban
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243655 (2020)
PLoS ONE
PLoS ONE
X-linked Dystonia-Parkinsonism (XDP) is a neurodegenerative disease linked to an insertion of a SINE-VNTR-Alu (SVA)-type retrotransposon within an intron of TAF1. This SVA insertion induces aberrant TAF1 splicing and partial intron retention, thereby
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08493bdf9097888220d01a44333daaa9
https://doi.org/10.1371/journal.pone.0243655
https://doi.org/10.1371/journal.pone.0243655
Autor:
Trisha Multhaupt-Buell, Xandra O. Breakefield, Kyle Shin, Jyotsna Dhakal, D. Cristopher Bragg, Marisela E. Dy, Naoto Ito, David Shin, Noriko Wakabayashi-Ito, Christina H. Liu, Christine A. Vaine, Nutan Sharma, William T. Hendriks
Publikováno v:
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 9, Iss 4, Pp 451-462 (2016)
Disease Models & Mechanisms, Vol 9, Iss 4, Pp 451-462 (2016)
X-linked dystonia-parkinsonism (XDP) is a hereditary neurodegenerative disorder involving a progressive loss of striatal medium spiny neurons. The mechanisms underlying neurodegeneration are not known, in part because there have been few cellular mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::292baf8766aee62237ab440e5f9d2204
http://europepmc.org/articles/PMC4852502
http://europepmc.org/articles/PMC4852502
Autor:
Christine A. Vaine, Ulrich Müller, Mark A. Ang, Jyotsna Dhakal, Laurie J. Ozelius, Xandra O. Breakefield, Mai-Linh Ton, Christopher T. Russo, Patrick Acuna, Kotchaphorn Mangkalaphiban, David Shin, Anne Cheng, William T. Hendriks, Trisha Multhaupt-Buell, Taylor N. Franceour, Naoto Ito, D. Cristopher Bragg, Rachita Yadav, Nutan Sharma, Nichita J. Kulkarni, Criscely L. Go
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The genetic basis of X-Linked dystonia-parkinsonism (XDP) has been difficult to unravel, in part because all patients inherit the same haplotype of seven sequence variants, none of which has ever been identified in control individuals. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25eb8b3bc8a4de0912e55ec3069f654a
https://doi.org/10.1073/pnas.1712526114
https://doi.org/10.1073/pnas.1712526114
Autor:
Harrison Brand, Naoto Ito, Benjamin Currall, Jyotsna Dhakal, David M. Jaffe, Daniel Henderson, Laurie J. Ozelius, Criscely L. Go, Michael E. Talkowski, Patrick Acuna, Dadi Gao, William T. Hendriks, Brian J. Wainger, Tatsiana Aneichyk, Yechiam Sapir, Ryan L. Collins, Rachita Yadav, Christine A. Vaine, Neil I. Weisenfeld, Marisela E. Dy, Nutan Sharma, Xandra O. Breakefield, D. Cristopher Bragg, Alexei Stortchevoi, David Shin, Caroline Antolik, Carrie Hanscom, Ashok Ragavendran
X-linked Dystonia-Parkinsonism (XDP) is a Mendelian neurodegenerative disease endemic to the Philippines. We integrated genome and transcriptome assembly with induced pluripotent stem cell-based modeling to identify the XDP causal locus and potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::314a224e61c7d9fe5928589d2381547a
Autor:
Evelyn A. Kurt-Jones, Eunji Lee, Christine A. Vaine, Robert W. Finberg, Jintao Zhu, Ryan C. Hayward, Milan K. Patel
Publikováno v:
The Journal of Immunology. 190:3525-3532
Polymeric microparticles have been widely investigated as platforms for delivery of drugs, vaccines, and imaging contrast agents and are increasingly used in a variety of clinical applications. Microparticles activate the inflammasome complex and ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a20271a21b3a38632b0106cc1b695e
https://doi.org/10.4049/jimmunol.1200492
https://doi.org/10.4049/jimmunol.1200492
Autor:
Christina H. Liu, Nutan Sharma, Christine A. Vaine, Jyotsna Dhakal, William T. Hendriks, Kyle Shin, David Shin, D. Cristopher Bragg
Publikováno v:
Neurobiology of Disease, Vol 100, Iss, Pp 108-118 (2017)
X-linked Dystonia-Parkinsonism (XDP) is a progressive neurodegenerative disease involving the loss of medium spiny neurons within the striatum. An XDP-specific haplotype has been identified, consisting of seven sequence variants which cluster around
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb39a8f02a0b8ca14044de581d74622a
https://pubmed.ncbi.nlm.nih.gov/28017799
https://pubmed.ncbi.nlm.nih.gov/28017799