Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Christine A. Holtkamp"'
Publikováno v:
American journal of hematology. 33(4)
Hemophiliacs often have mild anemia, and hemolysis has been suggested as the likely mechanism on the basis of the reduced serum haptoglobin values frequently observed in these patients. It has been suggested that hypohaptoglobinemia results from isoh
Publikováno v:
The American journal of pediatric hematology/oncology. 12(3)
The bleeding time, the most frequently performed test reflecting in vivo platelet function, is the duration of blood flow from a standardized incision on the volar surface of the forearm. Normal values have been determined in adult subjects, but with
Publikováno v:
American Journal of Clinical Pathology. 91:45-51
A number of variables affect the result of the bleeding time, the most frequently used test assessing primary hemostasis. Although the test is now usually performed with one of several commercially available disposable devices, most previous studies
Publikováno v:
Medical and Pediatric Oncology. 8:7-14
Antithrombin III levels were measured in serum before, during, and after therapy with three different dosage regimens of L-asparaginase in 11 children with acute lymphoblastic leukemia. Levels determined by both functional and immunologic methods wer
Publikováno v:
Pediatrics. 81:840-845
Mild leukopenia and thrombocytopenia are common in multitransfused hemophiliacs. Because little attention has previously been directed to measurements of erythropoiesis in these patients, we prospectively examined hemoglobin concentration and RBC ind
Publikováno v:
Pediatrics. 72:93-98
Although the epidemiology and pathophysiology of serious bacterial infection in homozygous sickle cell anemia (SS disease) have become increasingly well understood, information about infection risk and splenic reticuloendothelial function in hemoglob
Publikováno v:
The Journal of Pediatrics. 106:239-242
We studied splenic function in children with cancer by quantitation of pitted, or pocked, erythrocytes (pocked RBC count), that is, the percentage of erythrocytes containing one or more membrane-bound vesicles, as determined by phase interference mic
Publikováno v:
Thrombosis and Haemostasis. 46:690-693
SummaryIn view of prior reports of platelet activation in the sickling disorders, platelet aggregation, malondialdehyde (MDA) production following stimulation with N-ethylmaleimide, and/or production time (survival) measurements were examined in 44 c
Publikováno v:
British Journal of Haematology. 49:455-464
Several investigators have reported defective ristocetin-induced platelet aggregation (RIPA) in individuals whose red blood cells contain sickle haemoglobin, but the race of control subjects in these studies was not stated. Therefore, maximal amplitu
Publikováno v:
Journal of Pediatric Hematology/Oncology. 6:355-362
The efficacy of corticosteroids in childhood acute idiopathic thrombocytopenic purpura (ITP) is controversial and has infrequently been evaluated in a controlled randomized fashion. We administered prednisone (2 mg/kg/day for 14 days with subsequent