Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Christine A. Glidewell-Kenney"'
Autor:
Christine A. Glidewell-Kenney, Adaku M. Uzo-Okereke, Djurdjica Coss, Navarre Gutierrez-Reed, Crystal Trang, Pamela L. Mellon, Paul P. Shao
Publikováno v:
Endocrinology. 155:3909-3919
Mutations in neurokinin B (NKB) and its receptor, NK3R, were identified in human patients with hypogonadotropic hypogonadism, a disorder characterized by lack of puberty and infertility. Further studies have suggested that NKB acts at the level of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fda12a554a44c81d763cf08dd9c2274
https://doi.org/10.1210/en.2014-1263
https://doi.org/10.1210/en.2014-1263
Autor:
Kenichi Inagaki, Kishio Toma, Kanako Ogura-Ochi, Christine A. Glidewell-Kenney, Tomohiro Terasaka, Mark A. Lawson, Fumio Otsuka, Eri Nakamura, Naoko Tsukamoto, Hirofumi Makino
Publikováno v:
Molecular and Cellular Endocrinology. 381(1-2):8-15
Reproduction is integrated by interaction of neural and hormonal signals converging on hypothalamic neurons for controlling gonadotropin-releasing hormone (GnRH). Kisspeptin, the peptide product of the kiss1 gene and the endogenous agonist for the GR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bf3cda7c05b03130a8c674359d6eb31
https://ousar.lib.okayama-u.ac.jp/52807
https://ousar.lib.okayama-u.ac.jp/52807
Autor:
Alexander S. Kauffman, Varykina G. Thackray, Matthew C. Poling, Sheila J. Semaan, Christine A. Glidewell-Kenney, Pamela L. Mellon, Kristen P. Tolson, Nahoko Iwata, Kellie M Breen, Nicholas J. G. Webster, Shunichi Shimasaki, Antoni J. Duleba, Genevieve E. Ryan, Elisabet Stener-Victorin
Publikováno v:
Biology of Reproduction. 93
Polycystic ovary syndrome (PCOS) pathophysiology is poorly understood, due partly to lack of PCOS animal models fully recapitulating this complex disorder. Recently, a PCOS rat model using letrozole (LET), a nonsteroidal aromatase inhibitor, mimicked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1579a6a65c9d527753d27bbcd0ee6e28
https://doi.org/10.1095/biolreprod.115.131631
https://doi.org/10.1095/biolreprod.115.131631
Autor:
Macarena Pampillo, Maryse R. Ahow, Pamela L. Mellon, Le Min, Christine A. Glidewell-Kenney, Moshmi Bhattacharya, Stuart A. Tobet, Andy V. Babwah, Connor P. Nash, Rona S. Carroll, Kathleen Soltis, Ursula B. Kaiser, Junping Wen
Publikováno v:
Endocrinology. 155(11)
Hypothalamic GnRH is the master regulator of the neuroendocrine reproductive axis, and its secretion is regulated by many factors. Among these is kisspeptin (Kp), a potent trigger of GnRH secretion. Kp signals via the Kp receptor (KISS1R), a Gαq/11-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9e2ec386a821fdbfd5a6f3acd13691a
https://pubmed.ncbi.nlm.nih.gov/25147978
https://pubmed.ncbi.nlm.nih.gov/25147978
Publikováno v:
Journal of Endocrinology. 170:601-607
Androgens have a profound effect on the hypothalamic-pituitary axis by reducing the synthesis and release of the pituitary gonadotropin LH. The effect on LH is partly a consequence of a direct, steroid-dependent action on pituitary function. Although
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758e8ccf2d0baf3580324667184081f6
https://doi.org/10.1677/joe.0.1700601
https://doi.org/10.1677/joe.0.1700601
Autor:
Pamela L. Mellon, Anita K. Iyer, Paul P. Shao, Christine A. Glidewell-Kenney, Anna M. H. Grove, Jason D. Meadows
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 27(3)
Genetic studies in human patients with idiopathic hypogonadotropic hypogonadism (IHH) identified mutations in the genes that encode neurokinin B (NKB) and the neurokinin 3 receptor (NK3R). However, determining the mechanism whereby NKB regulates gona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2437ce6a7c599f172f43219f90de3bf
https://pubmed.ncbi.nlm.nih.gov/23393128
https://pubmed.ncbi.nlm.nih.gov/23393128