Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Christine A. Farthing"'
Publikováno v:
J Chromatogr B Analyt Technol Biomed Life Sci
A rapid and selective method for the quantitation of neurotransmitters, l-Glutamic acid (GA) and γ–Aminobutyric acid (GABA), was developed and validated using gas chromatography-tandem mass spectrometry (GC–MS/MS). The novel method utilized a ra
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 38:1173-1178
As a means to evaluate the role of organic solute carriers in CNS homeostasis, a simple and rapid high-performance liquid chromatographic method utilizing ultraviolet and electrochemical detectors was developed and validated for the simultaneous dete
Publikováno v:
Current Pharmaceutical Design. 20:1472-1486
A major function of the blood brain barrier (BBB) and blood cerebrospinal fluid barrier (BCSFB) is to exert selective control over the flux of organic cations and anions into and out of the CNS compartment. These barriers are dynamic tissues that acc
Autor:
Terri Larus, Itaf Fakhry, Todd W.B. Gehr, Christine A. Farthing, Michael Hindle, Lei Xi, Lynne Gehr, Domenic A. Sica, H. Thomas Karnes, Don Farthing, Les Edinboro
Publikováno v:
Luminescence. 26:65-75
A rapid and simple chemiluminescence method was developed for detection of inosine and hypoxanthine in human plasma. The method utilized a microplate luminometer with direct injectors to automatically dispense reagents during sample analysis. Enzymat
Autor:
Don Farthing, Domenic A. Sica, Lei Xi, Christine A. Farthing, Terri Larus, Saisudha Koka, Todd W.B. Gehr, Rakesh C. Kukreja, Itaf Fakhry
Publikováno v:
Journal of Chromatography B. 878:2891-2895
A simple and sensitive high-performance liquid chromatographic (HPLC) method utilizing fluorescence detection was developed for the determination of the phosphodiesterase type 5 inhibitor tadalafil in mouse plasma. This method utilizes a simple sampl
Autor:
Christine A. Farthing, Don Farthing, Todd W.B. Gehr, Donald F. Brophy, Terri Larus, Itaf Fakhry, Lena Maynor
Publikováno v:
Chromatographia. 67:365-368
A simple high-performance liquid chromatographic (HPLC) method was developed for the simultaneous determination of cefepime and cefazolin in human plasma and dialysate. For component separation, the method utilized a C18 column with an aqueous mobile
Autor:
Christine A. Farthing, Domenic A. Sica, Terri Larus, H. Thomas Karnes, Don Farthing, Itaf Fakhry, Todd W.B. Gehr, Bill Wilson
Publikováno v:
Journal of Chromatography B. 854:158-164
A simple and sensitive high-performance liquid chromatography (HPLC) method utilizing ultraviolet (UV) detection was developed for the determination of inosine and hypoxanthine in human plasma. For component separation, a monolithic C(18) column at a
Publikováno v:
Experimental biology and medicine (Maywood, N.J.). 240(6)
Cardiac ischemia associated with acute coronary syndrome and myocardial infarction is a leading cause of mortality and morbidity in the world. A rapid detection of the ischemic events is critically important for achieving timely diagnosis, treatment
Autor:
Don Farthing, Christine A. Farthing, Domenic A. Sica, Itaf Fakhry, Todd W.B. Gehr, Terri Larus, Sid Ghosh, Michael Vranian
Publikováno v:
Journal of Chromatography B. 826:267-272
A simple high-performance liquid chromatographic (HPLC) method was developed for the simultaneous determination of iohexol, iothalamate, p-aminohippuric acid (PAH) and n-acetyl-p-aminohippuric acid (n-acetyl-PAH) in human plasma and urine. A C(18) co
Autor:
Terri Larus, Donald F. Brophy, Alpha A. Fowler, Christine DeWilde, Seema Gupta, Don Farthing, Erika J. Martin, Robin Sculthorpe, Christine A. Farthing, Ramesh Natarajan, Aamer Syed, Bernard J. Fisher, Shelley Knowlson
Publikováno v:
Journal of Translational Medicine
Parenterally administered ascorbic acid modulates sepsis-induced inflammation and coagulation in experimental animal models. The objective of this randomized, double-blind, placebo-controlled, phase I trial was to determine the safety of intravenousl