Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Christine A. Cezar"'
Autor:
David J. Mooney, Christine A. Cezar, James C. Weaver, Herman H. Vandenburgh, Alizée Déléris, Stephen Kennedy, Charles M. Roco, Patrizia M. Spoerri
Publikováno v:
Biomaterials. 161:179-189
While providing the ability to magnetically enhance delivery rates, ferrogels have not been able to produce the various types of regulated delivery profiles likely needed to direct complex biological processes . For example, magnetically triggered re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e1e02d7fb20cb829fa87d16d59118c
https://doi.org/10.1016/j.biomaterials.2018.01.049
https://doi.org/10.1016/j.biomaterials.2018.01.049
Autor:
Praveen R. Arany, Bo Ri Seo, Christine A. Cezar, David J. Mooney, Sarah A. Vermillion, Herman H. Vandenburgh
Cell transplantation is a promising therapeutic strategy for the treatment of traumatic muscle injury in humans. Previous investigations have typically focused on the identification of potent cell and growth factor treatments and optimization of spat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe6873eddccab5590002d17e2ae81a8
https://europepmc.org/articles/PMC5641972/
https://europepmc.org/articles/PMC5641972/
Autor:
David J. Mooney, Georg N. Duda, Conor J. Walsh, Christine A. Cezar, Herman H. Vandenburgh, Ellen T. Roche
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 113(6)
Severe skeletal muscle injuries are common and can lead to extensive fibrosis, scarring, and loss of function. Clinically, no therapeutic intervention exists that allows for a full functional restoration. As a result, both drug and cellular therapies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa8293c2840b5e8d20a91835fbc782c
https://pubmed.ncbi.nlm.nih.gov/26811474
https://pubmed.ncbi.nlm.nih.gov/26811474
Autor:
Cristina Borselli, David J. Mooney, Christine A. Cezar, Herman H. Vandenburgh, Dmitry Shvartsman
Publikováno v:
Biomaterials. 32:8905-8914
Many cell types of therapeutic interest, including myoblasts, exhibit reduced engraftment if cultured prior to transplantation. This study investigated whether polymeric scaffolds that direct cultured myoblasts to migrate outwards and repopulate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90fa39519719772b0c6d62c2ceffaf75
https://doi.org/10.1016/j.biomaterials.2011.08.019
https://doi.org/10.1016/j.biomaterials.2011.08.019
Autor:
Cathal J. Kearney, Christine A. Cezar, Zhigang Suo, David J. Mooney, Xuanhe Zhao, Jaeyun Kim, Nathaniel Huebsch
Biological systems are exquisitely sensitive to the location and timing of physiologic cues and drugs. This spatiotemporal sensitivity presents opportunities for developing new therapeutic approaches. Polymer-based delivery systems are used extensive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34da331f503dd21bd5dfbfa7fca1be23
https://europepmc.org/articles/PMC4103344/
https://europepmc.org/articles/PMC4103344/
Autor:
Yevgeny Brudno, Herman H. Vandenburgh, Corey M. McCann, David J. Mooney, Cathal J. Kearney, John Koullias, Nhi Ho, Christine A. Cezar, Erin M. Anderson, Juan Carlos Tapia, Jeff W. Lichtman, Kangwon Lee, Hannah Storrie-White, Dmitry Shvartsman
Tissue reinnervation following trauma, disease, or transplantation often presents a significant challenge. Here, we show that the delivery of vascular endothelial growth factor (VEGF) from alginate hydrogels ameliorates loss of skeletal muscle innerv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a16deb58f604923c915f8ac33b38e27
https://europepmc.org/articles/PMC4089004/
https://europepmc.org/articles/PMC4089004/
Autor:
James C. Weaver, Manav Mehta, Christine A. Cezar, Herman H. Vandenburgh, Stephen Kennedy, David J. Mooney, Luo Gu
Publikováno v:
Advanced healthcare materials. 3(11)
Ferrogels are an attractive material for many biomedical applications due to their ability to deliver a wide variety of therapeutic drugs on-demand. However, typical ferrogels have yet to be optimized for use in cell-based therapies, as they possess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7763b966493dad417d77ebed242b0c69
https://pubmed.ncbi.nlm.nih.gov/24862232
https://pubmed.ncbi.nlm.nih.gov/24862232
Autor:
Xuanhe Zhao, Jaeyun Kim, Christine A. Cezar, Nathaniel Huebsch, Kangwon Lee, Kamal Bouhadir, David J. Mooney
Porous biomaterials have been widely used as scaffolds in tissue engineering and cell-based therapies. The release of biological agents from conventional porous scaffolds is typically governed by molecular diffusion, material degradation, and cell mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e25762501844aadc7fa27557e39e2b9f
https://europepmc.org/articles/PMC3017202/
https://europepmc.org/articles/PMC3017202/
Autor:
David J. Mooney, Jeff W. Lichtman, Hannah Storrie, Dmitry Shvartsman, Cristina Borselli, Herman Vandenburgh, Frank Benesch-Lee, Christine A. Cezar
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 107(8)
Regenerative efforts typically focus on the delivery of single factors, but it is likely that multiple factors regulating distinct aspects of the regenerative process (e.g., vascularization and stem cell activation) can be used in parallel to affect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9668d8f62b204d2d56a60359f5d2ebb5
https://pubmed.ncbi.nlm.nih.gov/21082885
https://pubmed.ncbi.nlm.nih.gov/21082885