Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Christine A. Cartwright"'
Publikováno v:
Nursing standard (Royal College of Nursing (Great Britain) : 1987). 36(12)
Healthy ageing has been defined as the process of developing and maintaining the functional ability that enables well-being in older age. However, as people age, many will develop chronic diseases. Therefore, while life expectancy worldwide has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::613470dd18bcd4e9edc6bb9f14773547
https://pubmed.ncbi.nlm.nih.gov/34569199
https://pubmed.ncbi.nlm.nih.gov/34569199
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 314:G1-G13
Previously, we showed that receptor for activated C kinase 1 (Rack1) regulates growth of colon cells in vitro, partly by suppressing Src kinase activity at key cell cycle checkpoints, in apoptotic and cell survival pathways and at cell-cell adhesions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::706d07a45574df6be2cd6c16e4d21f44
https://doi.org/10.1152/ajpgi.00240.2017
https://doi.org/10.1152/ajpgi.00240.2017
Autor:
Qin Zhou, Natasha T Snider, Jian Liao, Daniel H Li, Anita Hong, Nam-On Ku, Christine A Cartwright, M Bishr Omary
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13538 (2010)
Keratin polypeptide 19 (K19) is a type I intermediate filament protein that is expressed in stratified and simple-type epithelia. Although K19 is known to be phosphorylated on tyrosine residue(s), conclusive site-specific characterization of these re
Externí odkaz:
https://doaj.org/article/65a0e5e29b9b4f0ca1da90cfc1f582a8
Autor:
Andrew A. Shelton, Gerald J. Berry, Kirsten Regalia, George Triadafilopoulos, Christine A. Cartwright
Publikováno v:
Digestive Diseases and Sciences. 62:64-67
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82ba819c42f27ffca67b95c66e36a120
https://doi.org/10.1007/s10620-015-3993-1
https://doi.org/10.1007/s10620-015-3993-1
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 314(2)
Previously, we generated mouse models of Rack1 deficiency to identify key functions for Rack1 in regulating growth of intestinal epithelia: suppressing crypt cell proliferation and regeneration, promoting differentiation and apoptosis, and repressing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f28af1e8d21339533b83ffc7fbe2cfd9
https://pubmed.ncbi.nlm.nih.gov/29025732
https://pubmed.ncbi.nlm.nih.gov/29025732
Publikováno v:
Biochemical and Biophysical Research Communications. 352:423-430
Cascades of kinases and phosphatases are regulated by selective protein-protein interactions that are essential for signal transduction. Peptide modulators of these interactions have been used to dissect the function of individual components of the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53509cdea1825a8d60cd5e742ee75ef
https://doi.org/10.1016/j.bbrc.2006.11.034
https://doi.org/10.1016/j.bbrc.2006.11.034
Autor:
Kelly C. Lee, Vidya Mamidipudi, Laura D. Miller, N K Dhillon, T Parman, Christine A. Cartwright
Publikováno v:
Oncogene. 26:2914-2924
Previously, we showed that Src tyrosine kinases are activated early in the development of human colon cancer and are suppressed as intestinal cells differentiate. We identified RACK1 as an endogenous substrate, binding partner and inhibitor of Src. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1ee4f9269746ae3329cce7093cfbf63
https://doi.org/10.1038/sj.onc.1210091
https://doi.org/10.1038/sj.onc.1210091
Publikováno v:
FEBS Letters. 567:321-326
Cancer cells are capable of serum- and anchorage-independent growth, and focus formation on monolayers of normal cells. Previously, we showed that RACK1 inhibits c-Src kinase activity and NIH3T3 cell growth. Here, we show that RACK1 partially inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58271782820013ac913bdb58a16d1260
https://doi.org/10.1016/j.febslet.2004.03.125
https://doi.org/10.1016/j.febslet.2004.03.125
Publikováno v:
The American Journal of Surgical Pathology. 28:365-373
Cytomegalovirus (CMV) infection is reported to be a cause of steroid-refractory ulcerative colitis (UC), but the strength of this association has not been tested in a case control study. Controlled studies have also not been performed to determine th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54282acf3a9fb8a2cf9b99abfb829bf3
https://doi.org/10.1097/00000478-200403000-00009
https://doi.org/10.1097/00000478-200403000-00009
Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity
Autor:
John P. Lynch, Young-Kwon Hong, Jessica M. Terry, Nicholas R. Smith, Melissa H. Wong, Phillip Belgrader, Rajan Jain, Benedict Anchang, Martin G. Martin, Christine A. Cartwright, David T. Breault, Grace X.Y. Zheng, Kelly Roelf, Jonathan I. Epstein, Sylvia K. Plevritis, John S. Kaddis, Kathryn A. Larkin, Mary Ann S. Chrissy, Esther Cynn, Stéphane C. Boutet, Arnold Han, Joyce C. Niland, Solongo B. Ziraldo, Courtney W. Houchen, Ruben I. Calderon, Susan J. Henning, Susan M. Grimes, Komal Mandleywala, Linheng Li, Richard J. von Furstenberg, Fengchao Wang, Paige S. Davies, Parthasarathy Chandrakesan, Calvin J. Kuo, Olivier Gevaert, Zhuan fen Cheng, Tarjei S. Mikkelsen, Christina Curtis, Julie Wilhelmy, David C Corney, Xiaoyi Hu, Chris Probert, Kelley S. Yan, Randal May, Hanlee P. Ji, Jill L. Carrington
Publikováno v:
Cell stem cell, vol 21, iss 1
Several cell populations have been reported to possess intestinal stem cell (ISC) activity during homeostasis and injury-induced regeneration. Here, we explored inter-relationships between putative mouse ISC populations by comparative RNA-sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac863a7e8ef4c917c73213806060cccf
https://doi.org/10.1016/j.stem.2017.06.014
https://doi.org/10.1016/j.stem.2017.06.014