Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Christine A Sinkey"'
Publikováno v:
Heart and Mind, Vol 2, Iss 3, Pp 78-84 (2018)
Background: Previous research on bipolar disorder demonstrates greater-than-expected vascular dysfunction later in the course of illness, proportionate to the cumulative burden of mood symptoms. However, little is known about the effect of acute mood
Externí odkaz:
https://doaj.org/article/83b1832479f94c818d1f93484708de75
Autor:
Margaret L. Bayless, William G. Haynes, William I. Sivitz, Christine A. Sinkey, Sheila M. Wayson
Publikováno v:
Journal of Diabetes and its Complications. 21:149-157
Objectives Arterial dysfunction occurs in obesity and diabetes. However, there is uncertainty about the relative contribution of endothelial dysfunction, smooth muscle dysfunction, or adrenergic hyperresponsiveness. Methods and Results We examined fo
Autor:
William G. Haynes, Dinesh H. Jagasia, Christine A. Sinkey, Michelle Maifeld, Bradley J. VanVoorhis, Anuja Dokras
Publikováno v:
Fertility and Sterility. 86:1702-1709
Objective Polycystic ovary syndrome (PCOS) is associated with biochemical evidence of early atherosclerosis; however, data regarding vascular function are controversial. We hypothesized that resistance vessel function (mediated by the endothelium or
Publikováno v:
Diabetes. 51:734-742
Adrenergic responses are crucial for hypoglycemic recovery. Epinephrine increases glucose production, lipolysis, and peripheral insulin resistance as well as blood flow and glucose delivery. Sympathetic activation causes vasoconstriction and reduces
Autor:
Christine A. Sinkey, Phyllis J. Stumbo, Geetha Raghuveer, Catherine A. Chenard, William G. Haynes
Publikováno v:
The American Journal of Cardiology. 88:285-290
We tested if vitamin E, a fat-soluble antioxidant, prevents resistance vessel endothelial dysfunction caused by methionine-induced hyperhomocysteinemia in humans. Moderate elevations in plasma homocysteine concentrations are associated with atheroscl
Autor:
Catherine A Chenard, William G. Haynes, Christine A Sinkey, G.Steinar Gudmundsson, Phyllis J Stumbo
Publikováno v:
The American Journal of Cardiology. 85:381-385
A single high-fat meal transiently impairs conduit vessel endothelial function. We tested the hypothesis that transient moderate hypertriglyceridemia by consumption of a high-fat meal impairs forearm resistance vessel endothelial function. Fifteen he
Publikováno v:
Metabolism. 48:1575-1583
During hypoglycemia, hepatic glucose production increases and peripheral glucose utilization decreases. Systemic beta-adrenergic blockade during hypoglycemia increases peripheral glucose utilization. To explore the local effects of increased alpha- a
Publikováno v:
Journal of Diabetes and its Complications. 13:17-22
To explore the effects of the acute induction of hyperglycemia on sympathetic activity and vascular function we studied eight normal control subjects (28 +/- 3 years of age). Muscle sympathetic nerve activity (MSNA) and forearm vascular resistance (F
Publikováno v:
Journal of Diabetes and its Complications. 12:307-310
Our objective was to determine whether microneurographically determined muscle sympathetic nerve activity (MSNA) levels are equally reproducible in control and insulin-dependent diabetes mellitus (IDDM) subjects. We used a retrospective review of MSN
Publikováno v:
American Journal of Hypertension. 11:1312-1320
Insulin resistance and elevated sympathetic nerve activity (SNA) are observed in young borderline hypertensive humans. A positive family history of hypertension (FH) is a strong risk factor for developing hypertension. To assess whether insulin resis