Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Christine A Rygiel"'
Autor:
Rebekah L. Petroff, Raymond G. Cavalcante, Justin A. Colacino, Jaclyn M. Goodrich, Tamara R. Jones, Claudia Lalancette, Rachel K. Morgan, Kari Neier, Bambarendage P. U. Perera, Christine A. Rygiel, Laurie K. Svoboda, Kai Wang, Maureen A. Sartor, Dana C. Dolinoy
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: The developing epigenome changes rapidly, potentially making it more sensitive to toxicant exposures. DNA modifications, including methylation and hydroxymethylation, are important parts of the epigenome that may be affected by environm
Externí odkaz:
https://doaj.org/article/5b930414f936410f8ed12f4473232a85
Autor:
Laurie K. Svoboda, Kari Neier, Kai Wang, Raymond G. Cavalcante, Christine A. Rygiel, Zing Tsai, Tamara R. Jones, Siyu Liu, Jaclyn M. Goodrich, Claudia Lalancette, Justin A. Colacino, Maureen A. Sartor, Dana C. Dolinoy
Publikováno v:
Epigenetics, Vol 16, Iss 10, Pp 1102-1122 (2021)
Early developmental environment can influence long-term health through reprogramming of the epigenome. Human environmental epigenetics studies rely on surrogate tissues, such as blood, to assess the effects of environment on disease-relevant but inac
Externí odkaz:
https://doaj.org/article/ba9c41a8e56a4e1794df3be4c666cf60
Autor:
Kai Wang, Siyu Liu, Laurie K. Svoboda, Christine A. Rygiel, Kari Neier, Tamara R. Jones, Justin A. Colacino, Dana C. Dolinoy, Maureen A. Sartor
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Lead (Pb) is a well-known toxicant that interferes with the development of a child’s nervous and metabolic systems and increases the risk of developing diseases later in life. Although studies have investigated epigenetic effects associated with Pb
Externí odkaz:
https://doaj.org/article/8cacfd453a854541a3d19c94939a7758
Autor:
Howard Hu, Jaclyn M. Goodrich, Karen E. Peterson, Maritsa Solano-González, Christine A Rygiel, Adriana Mercado-García, Dana C. Dolinoy, Martha María Téllez-Rojo
Publikováno v:
Environmental Health Perspectives
Background: Gestational lead (Pb) exposure can adversely affect offspring health through multiple mechanisms, including epigenomic alterations via DNA methylation (5mC) and hydroxymethylation (5hmC), an intermediate in oxidative demethylation. Most c
Autor:
Tamara R. Jones, Kelly M. Bakulski, Jaclyn M. Goodrich, Martha María Téllez-Rojo, Max T. Aung, Karen E. Peterson, Lourdes Schnaas, Dana C. Dolinoy, Maritsa Solano-González, Howard Hu, Christine A Rygiel, Erika Marcela, Wei Perng
Publikováno v:
Environmental Epigenetics
Early-life lead (Pb) exposure has been linked to adverse neurodevelopmental outcomes. Recent evidence has indicated a critical role of DNA methylation (DNAm) in cognition, and Pb exposure has also been shown to alter DNAm. However, it is unknown whet
Autor:
Tamara R. Jones, Christine A Rygiel, Justin A. Colacino, Maureen A. Sartor, Dana C. Dolinoy, Laurie K. Svoboda, Siyu Liu, Kari Neier, Kai Wang, Raymond G. Cavalcante
Publikováno v:
Environmental Epigenetics
Di(2-ethylhexyl) phthalate (DEHP) is a type of phthalate plasticizer found in a variety of consumer products and poses a public health concern due to its metabolic and endocrine disruption activities. Dysregulation of epigenetic modifications, includ
Autor:
Justin A. Colacino, Kari Neier, Siyu Liu, Tamara R. Jones, Maureen A. Sartor, Jaclyn M. Goodrich, Zing Tsung-Yeh Tsai, Raymond G. Cavalcante, Dana C. Dolinoy, Christine A Rygiel, Laurie K. Svoboda, Kai Wang, Claudia Lalancette
Publikováno v:
Epigenetics
Early developmental environment can influence long-term health through reprogramming of the epigenome. Human environmental epigenetics studies rely on surrogate tissues, such as blood, to assess the effects of environment on disease-relevant but inac
Autor:
Wei Perng, M.M. Tellez-Rojo, Karen E. Peterson, Howard Hu, Jaclyn M. Goodrich, Dana C. Dolinoy, Maritsa Solano, Tamara R. Jones, Christine A Rygiel
Publikováno v:
ISEE Conference Abstracts. 2020
Novel TMEM98, MFRP, PRSS56 variants in a large United States high hyperopia and nanophthalmos cohort
Autor:
Sarah J. Garnai, Robert B. Hufnagel, Shivani S Kamat, Ehsan Ullah, Brian P. Brooks, Shahzad I. Mian, Grant M. Comer, Bernadete Ayres, Julia E. Richards, Steven M. Archer, Monte A. Del Monte, Laryssa A. Huryn, Sayoko E Moroi, Bin Guan, Christine A Rygiel, Philip Lieu, Jasmine Y Serpen, Hemant Pawar, Laurel Wiinikka-Buesser, Lev Prasov, Cagri G. Besirli, Kayla Johnson, Susan G. Elner
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Nanophthalmos is a rare condition defined by a small, structurally normal eye with resultant high hyperopia. While six genes have been implicated in this hereditary condition (MFRP, PRSS56, MYRF, TMEM98, CRB1,VMD2/BEST1), the relative contribution of
Autor:
Tamara R. Jones, Wei Perng, Martha María Téllez-Rojo, Maritsa Solano, Dana C. Dolinoy, Karen E. Peterson, Christine A Rygiel, Jaclyn M. Goodrich, Howard Hu
Publikováno v:
Epigenetics Insights, Vol 13 (2020)
Epigenetics Insights
Epigenetics Insights
Gestational exposure to lead (Pb) adversely impacts offspring health through multiple mechanisms, one of which is the alteration of the epigenome including DNA methylation. This study aims to identify differentially methylated CpG sites associated wi