Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Christine A Bricault"'
Autor:
P J Klasse, Thomas J Ketas, Christopher A Cottrell, Gabriel Ozorowski, Gargi Debnath, Diawoye Camara, Erik Francomano, Pavel Pugach, Rajesh P Ringe, Celia C LaBranche, Marit J van Gils, Christine A Bricault, Dan H Barouch, Shane Crotty, Guido Silvestri, Sudhir Kasturi, Bali Pulendran, Ian A Wilson, David C Montefiori, Rogier W Sanders, Andrew B Ward, John P Moore
Publikováno v:
PLoS Pathogens, Vol 14, Iss 2, p e1006913 (2018)
The native-like, soluble SOSIP.664 trimer based on the BG505 clade A env gene of HIV-1 is immunogenic in various animal species, of which the most studied are rabbits and rhesus macaques. The trimer induces autologous neutralizing antibodies (NAbs) c
Externí odkaz:
https://doaj.org/article/62425485d58a4e9caedc9d4b0c68522e
Autor:
Xiaoli Pan, Sheila N. López Acevedo, Camille Cuziol, Evelyn De Tavernier, Ahmed S. Fahad, Priyobarta S. Longjam, Sambasiva P. Rao, David Aguilera-Rodríguez, Mathilde Rezé, Christine A. Bricault, Matías F. Gutiérrez-González, Matheus Oliveira de Souza, Joshua M. DiNapoli, Emmanuelle Vigne, Melody A. Shahsavarian, Brandon J. DeKosky
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Molecular characterization of antibody immunity and human antibody discovery is mainly carried out using peripheral memory B cells, and occasionally plasmablasts, that express B cell receptors (BCRs) on their cell surface. Despite the importance of p
Externí odkaz:
https://doaj.org/article/49fb3a23f5d142acb94df6b620d91928
Autor:
Scott A. Rush, Gurpreet Brar, Ching-Lin Hsieh, Emilie Chautard, Jennifer N. Rainho-Tomko, Chris D. Slade, Christine A. Bricault, Ana Kume, James Kearns, Rachel Groppo, Sophia T. Mundle, Linong Zhang, Danilo Casimiro, Tong-Ming Fu, Joshua M. DiNapoli, Jason S. McLellan
Publikováno v:
Cell reports. 40(12)
Human metapneumovirus (hMPV) is a major cause of acute respiratory tract infections in infants and the elderly for which there are no approved vaccines or antibody therapies. The viral fusion (F) glycoprotein is required for entry and is the primary
Autor:
David Jetton, Christine A. Bricault, Ramya Nityanandam, Jean Pierre Schatzmann Peron, Marinela Kirilova, Zhenfeng Li, Paolo Marinho de Andrade Zanotto, Noe B. Mercado, Michael R. Boyd, George H. Neubauer, Peter Abbink, Rafael De La Barrera, Dan H. Barouch, Alexander Badamchi-Zadeh, Kenneth H. Eckels, Joseph P. Nkolola, David Ng’ang’a, Patricia B. Giglio, M. Justin Iampietro, Stephen J. Thomas, Lori F. Maxfield, Richard G. Jarman, Nelson L. Michael, Rafael A. Larocca, Erica N. Borducchi, Edward T. Moseley
Publikováno v:
Nature
Zika virus (ZIKV) is a flavivirus that is responsible for an unprecedented current epidemic in Brazil and the Americas1,2. ZIKV has been causally associated with fetal microcephaly, intrauterine growth restriction, and other birth defects in both hum
Autor:
Rafael A. Larocca, Pablo Penaloza-MacMaster, Christine A. Bricault, Michael S. Seaman, Nicholas M. Provine, Alexander Badamchi-Zadeh, Dan H. Barouch, Erica N. Borducchi
Publikováno v:
Journal of Virology
We have recently demonstrated that CD4 + T cell help is required at the time of adenovirus (Ad) vector immunization for the development of functional CD8 + T cell responses, but the temporal requirement for CD4 + T cell help for the induction of anti
Autor:
Lindsey Gillis, Fadi Ghantous, Bronwyn M. Gunn, Christine A. Bricault, James M. Kovacs, James R. Perry, Michael S. Seaman, Nicole A. Doria-Rose, Kathryn E. Stephenson, George H. Neubauer, Bing Chen, Dan H. Barouch, Joseph P. Nkolola, John R. Mascola, Krisha McKee, Alexander Badamchi-Zadeh, Galit Alter, Jennifer L. Shields, Julia Jennings
Publikováno v:
Journal of Virology
A vaccination regimen capable of eliciting potent and broadly neutralizing antibodies (bNAbs) remains an unachieved goal of the HIV-1 vaccine field. Here, we report the immunogenicity of longitudinal prime/boost vaccination regimens with a panel of H
Autor:
Christine A. Bricault, Karina Yusim, Michael S. Seaman, Hyejin Yoon, James Theiler, Elena E. Giorgi, Kshitij Wagh, Maxwell Theiler, Peter Hraber, Jennifer P. Macke, Edward F. Kreider, Gerald H. Learn, Beatrice H. Hahn, Johannes F. Scheid, James M. Kovacs, Jennifer L. Shields, Christy L. Lavine, Fadi Ghantous, Michael Rist, Madeleine G. Bayne, George H. Neubauer, Katherine McMahan, Hanqin Peng, Coraline Chéneau, Jennifer J. Jones, Jie Zeng, Christina Ochsenbauer, Joseph P. Nkolola, Kathryn E. Stephenson, Bing Chen, S. Gnanakaran, Mattia Bonsignori, LaTonya D. Williams, Barton F. Haynes, Nicole Doria-Rose, John R. Mascola, David C. Montefiori, Dan H. Barouch, Bette Korber
Publikováno v:
Cell Host & Microbe
Summary Eliciting HIV-1-specific broadly neutralizing antibodies (bNAbs) remains a challenge for vaccine development, and the potential of passively delivered bNAbs for prophylaxis and therapeutics is being explored. We used neutralization data from
Autor:
Michael R. Boyd, Marinela Kirilova, Vladimir Vrbanac, Peter Abbink, Dan H. Barouch, Po-Ting Liu, Christine A. Bricault, Lawrence J. Tartaglia, Noe B. Mercado, Andrew M. Tager, Ovini Nanayakkara, Rafael A. Larocca, Alexander Badamchi-Zadeh, Michael S. Seaman
Publikováno v:
Journal of Virology
Broadly neutralizing antibodies (bNAbs) are being explored for HIV-1 prevention and cure strategies. However, administration of purified bNAbs poses challenges in resource-poor settings, where the HIV-1 disease burden is greatest. In vivo vector-base
Autor:
Zi Han Kang, Christine A. Bricault, Rafael A. Larocca, Peter Abbink, Dan H. Barouch, M. Justin Iampietro, Nicholas M. Provine
Publikováno v:
Journal of Virology
Adenovirus (Ad) vectors are being investigated as vaccine candidates, but baseline antivector immunity exists in human populations to both human Ad (HuAd) and chimpanzee Ad (ChAd) vectors. In this study, we investigated the immunogenicity and cross-r
Autor:
Michael R. Boyd, Christine A. Bricault, Dan H. Barouch, Jill Barrett, Stephen R. Walsh, Janice Tennant, Daniel F. Hoft, Stephen J. Thomas, Peter Abbink, Leyi Lin, Alison E Kosel, Azra Blazevic, Rafael De La Barrera, Keith Meyer, Michael S. Seaman, Michael Koren, Sarah L. George, Peter Dawson, Karla Mosby, Jason Thompson, James D. Brien, Jessica L Ansel, Kathryn E. Stephenson, Melissa Walsh, Kenneth H. Eckels, Andrew J. Hale, Merlin L. Robb, C Sabrina Tan, Kristin Mills, Erica L Sondergaard, Kayvon Modjarrad, Rafael A. Larocca, Trevor A Crowell, Veronica Tonwe, Richard G. Jarman, Nelson L. Michael, Anne Basil
Summary Background A safe, effective, and rapidly scalable vaccine against Zika virus infection is needed. We developed a purified formalin-inactivated Zika virus vaccine (ZPIV) candidate that showed protection in mice and non-human primates against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::478f5f6919095a3e33a6551164991dcc
https://europepmc.org/articles/PMC5884730/
https://europepmc.org/articles/PMC5884730/