Nanoparticles facing the gut barrier: retention or mucosal absorption? Mechanisms and dependency to nanoparticle characteristics

Autor: Christine Vauthier, Christelle Zandanel, Magali Noiray, Gilles Ponchel

Publikováno v: International Journal of Pharmaceutics
International Journal of Pharmaceutics, Elsevier, 2021, pp.121147. ⟨10.1016/j.ijpharm.2021.121147⟩

International audience; A better knowledge on influence of nanomedicine characteristics on their biological efficacy and safety is expected to accelerate their clinical translation. This work aimed understanding of the oral fate of polymer-based nano

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34aca58b771f70d58a4ca92726b4e611
https://hal.archives-ouvertes.fr/hal-03372832

Practical Guidelines for the Characterization and Quality Control of Nanoparticles in the Pharmaceutical Industry

Autor: Fanny Varenne, Christine Vauthier

Publikováno v: Emerging Technologies for Nanoparticle Manufacturing ISBN: 9783030507022
Emerging Technologies for Nanoparticle Manufacturing
Emerging Technologies for Nanoparticle Manufacturing, Springer International Publishing, pp.487-508, 2021, ⟨10.1007/978-3-030-50703-9_23⟩

International audience; Nanomaterials are used in a wide range of applications bringing completely new properties to a material or considerable improving pristine material property. In the medical domain where they are named nanomedicines, their usef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8cba5b6809d7320509bfd62e3fc4ef
https://doi.org/10.1007/978-3-030-50703-9_23

Issues related with the analysis of nanomaterials

Autor: Christine Vauthier

Publikováno v: Handbook of nanomaterials in analytical chemistry
Handbook of nanomaterials in analytical chemistry, 2020, ⟨10.1016/B-978-0-12-816699-4.00019-0⟩

Objects with at least one external dimension under 100 nm are nanomaterials. Such materials display unique properties compared with bulk with same composition. They interest many fields of the industry including applications in medicines. Properties,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6120bf126df5348f3b59cde413c3eb38
https://doi.org/10.1016/b978-0-12-816699-4.00019-0

Characterization of nanomedicines’ surface coverage using molecular probes and capillary electrophoresis

Autor: Myriam Taverna, A. Benmalek, Fanny Varenne, I. Le Potier, Jean-Baptiste Coty, Claire Smadja, Christine Vauthier, O. Garsaa

Publikováno v: European Journal of Pharmaceutics and Biopharmaceutics
European Journal of Pharmaceutics and Biopharmaceutics, Elsevier, 2018, 130, pp.48-58. ⟨10.1016/j.ejpb.2018.06.014⟩

International audience; A faithful characterization of nanomedicine (NM) is needed for a better understanding of their in vivo outcomes. Size and surface charge are studied with well-established methods. However, other relevant parameters for the und

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b644820e272eff0727e7f3d8d91c292
https://doi.org/10.1016/j.ejpb.2018.06.014

Evaluation of zeta potential of nanomaterials by electrophoretic light scattering: Fast field reversal versus Slow field reversal modes

Autor: Gillian Barratt, Hervé Hillaireau, François-Xavier Legrand, Fanny Varenne, Christine Vauthier, Jérémie Botton, Jean-Baptiste Coty

Publikováno v: Talanta
Talanta, Elsevier, 2019, 205, pp.120062. ⟨10.1016/j.talanta.2019.06.062⟩

Zeta potential of nanomaterials designed to be used in nanomedicine is an important parameter to evaluate as it influences in vivo behaviour hence biological activity, efficacy and safety. As mentioned by the International Organization for Standardiz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70528a36b596a84843caa50d904e0bdc
https://hal.archives-ouvertes.fr/hal-02983998