Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Christine Etherington"'
Autor:
Heledd H Jarosz-Griffiths, Lindsey Gillgrass, Laura R Caley, Giulia Spoletini, Ian J Clifton, Christine Etherington, Sinisa Savic, Michael F McDermott, Daniel Peckham
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0304555 (2024)
Inflammation is a key driver in the pathogenesis of cystic fibrosis (CF). We assessed the effectiveness of elexacaftor/tezacaftor/ivacaftor (ETI) therapy on downregulating systemic and immune cell-derived inflammatory cytokines. We also monitored the
Externí odkaz:
https://doaj.org/article/caa59c7e9d2246b8a30553c4cecf4594
Autor:
Giulia Spoletini, Giles Fitch, Lindsey Gillgrass, Christine Etherington, Ian Clifton, Daniel G. Peckham
Publikováno v:
ERJ Open Research, Vol 8, Iss 2 (2022)
Externí odkaz:
https://doaj.org/article/1e0837ae2ec64611945eb75fc024fd57
Autor:
Heledd H Jarosz-Griffiths, Thomas Scambler, Chi H Wong, Samuel Lara-Reyna, Jonathan Holbrook, Fabio Martinon, Sinisa Savic, Paul Whitaker, Christine Etherington, Giulia Spoletini, Ian Clifton, Anil Mehta, Michael F McDermott, Daniel Peckham
Publikováno v:
eLife, Vol 9 (2020)
Previously, we showed that serum and monocytes from patients with CF exhibit an enhanced NLRP3-inflammasome signature with increased IL-18, IL-1β, caspase-1 activity and ASC speck release (Scambler et al. eLife 2019). Here we show that CFTR modulato
Externí odkaz:
https://doaj.org/article/e72e404e8886401f9e9b651bbc12b5a4
Autor:
Akhil Sawant, Giulia Spoletini, Paul Whitaker, Christine Etherington, Ian Clifton, Daniel Peckham
Publikováno v:
ERJ Open Research, Vol 4, Iss 1 (2018)
Externí odkaz:
https://doaj.org/article/863cca67142c426a959408f1f7b10e15
Publikováno v:
Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::556a6ffe95d89892ac8330ed6b155fc5
https://doi.org/10.1136/gutjnl-2022-basl.44
https://doi.org/10.1136/gutjnl-2022-basl.44
Publikováno v:
Pulmonary Medicine, Vol 2016 (2016)
Advances in the treatment and life expectancy of cystic fibrosis (CF) patients mean that motherhood is now a realistic option for many women with CF. This qualitative study explored the psychosocial impact and adjustments made when women with CF beco
Externí odkaz:
https://doaj.org/article/3971e9a4f74e4386b270fb5be67eada2
Autor:
Giulia Spoletini, S. Wright, N. Shaw, E. Williams, H.K. Chadwick, R. Watson, Daniel Peckham, Christine Etherington, K. Pollard, L. Haigh, A Wood, Ian Clifton, L Gillgrass
Publikováno v:
44th European Cystic Fibrosis Conference
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::339cffa7496d4d966fb4e83d79619dfc
Autor:
Christine Etherington, K. Pollard, Daniel Peckham, Paul Whitaker, Giulia Spoletini, Annette Johnstone, Michael Darby, Ian Clifton, R. Watson
Publikováno v:
Respir Care
BACKGROUND: Noninvasive ventilation (NIV) is routinely used to treat patients with cystic fibrosis and respiratory failure. However, evidence on its use is limited, with no data on its role in disease progression and outcomes. The aim of this study w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90e060b5e81aa5dbc43c1dfe03c4554
https://europepmc.org/articles/PMC9994063/
https://europepmc.org/articles/PMC9994063/
Autor:
Daniel Peckham, K. Pollard, Christine Etherington, Giulia Spoletini, R. Watson, Wang Yng Lim, Ian Clifton
Publikováno v:
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 20(5)
Background Exercise tolerance in people with CF and advanced lung disease is often reduced. While supplemental oxygen can improve oxygenation, it does not affect dyspnoea, fatigue or comfort. Nasal high-flow therapy (NHFT), thanks to its pathophysiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e344478561df8120272dfcd1d11b9cb
https://pubmed.ncbi.nlm.nih.gov/33814320
https://pubmed.ncbi.nlm.nih.gov/33814320
Autor:
K. Pollard, Wang Yng Lim, R. Watson, Daniel Peckham, Ian Clifton, Christine Etherington, Giulia Spoletini
Publikováno v:
Cystic fibrosis.
Background: Exercise tolerance in patients with CF and severe lung disease is limited by dyspnea and increased work of breathing. The aim of this study was to assess if NHFT, by virtue of its physiological effects, could improve exercise tolerance in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2143f31344926e0730b1c4fb0126bb88
https://doi.org/10.1183/13993003.congress-2020.365
https://doi.org/10.1183/13993003.congress-2020.365