Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Christine, Valfridsson"'
Autor:
Esther Nobs, Katie Laschanzky, Kristina Munke, Elin Movert, Christine Valfridsson, Fredric Carlsson
Publikováno v:
mBio, Vol 15, Iss 9 (2024)
ABSTRACT Serine protease inhibitors (serpins) constitute the largest family of protease inhibitors expressed in humans, but their role in infection remains largely unexplored. In infected macrophages, the mycobacterial ESX-1 type VII secretion system
Externí odkaz:
https://doaj.org/article/4022bdff1e414cb4bd739fee298dd640
Autor:
Elin Movert, Jaume Salgado Bolarin, Christine Valfridsson, Jorge Velarde, Steinar Skrede, Michael Nekludov, Ole Hyldegaard, Per Arnell, Mattias Svensson, Anna Norrby-Teglund, Kyu Hong Cho, Eran Elhaik, Michael R. Wessels, Lars Råberg, Fredric Carlsson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Variability in disease severity caused by a microbial pathogen is impacted by each infection representing a unique combination of host and pathogen genomes. Here, we show that the outcome of invasive Streptococcus pyogenes infection is regul
Externí odkaz:
https://doaj.org/article/e6892bfbcad24fc4a8d136c2cda1ce1b
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The common human pathogen Group A Streptococcus (GAS) causes superficial as well as invasive, life-threatening diseases. An increase in the occurrence of invasive GAS infection by strains of the M1 and M89 serotypes has been correlated with increased
Externí odkaz:
https://doaj.org/article/df567c634017498ca57fc7c85d18c0a2
Publikováno v:
Methods in Molecular Biology ISBN: 9781071632420
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c676700e257b1fe41aedea0a575cb667
https://doi.org/10.1007/978-1-0716-3243-7_18
https://doi.org/10.1007/978-1-0716-3243-7_18
Autor:
Elin Movert, Julia Lienard, Christine Valfridsson, Therése Nordström, Bengt Johansson-Lindbom, Fredric Carlsson
Publikováno v:
PLoS Pathogens, Vol 14, Iss 3, p e1006969 (2018)
From an evolutionary point of view a pathogen might benefit from regulating the inflammatory response, both in order to facilitate establishment of colonization and to avoid life-threatening host manifestations, such as septic shock. In agreement wit
Externí odkaz:
https://doaj.org/article/27a1f67bf820442597a0bfaf434defa4
Autor:
Dóra Hancz, Elsa Westerlund, Benedicte Bastiat-Sempe, Onkar Sharma, Christine Valfridsson, Lena Meyer, John F. Love, Maghnus O’Seaghdha, Michael R. Wessels, Jenny J. Persson
Publikováno v:
mBio, Vol 8, Iss 4 (2017)
ABSTRACT Group A Streptococcus (GAS) is a common human pathogen and the etiologic agent of a large number of diseases ranging from mild, self-limiting infections to invasive life-threatening conditions. Two prominent virulence factors of this bacteri
Externí odkaz:
https://doaj.org/article/ed60a73db88044dd80ac2bc414eea6eb
Autor:
Victoria Lovins, Elin Movert, Esther Nobs, Christine Valfridsson, Fredric Carlsson, Julia Lienard
Publikováno v:
Proceedings of the National Academy of Sciences. 117:1160-1166
Following mycobacterial entry into macrophages the ESX-1 type VII secretion system promotes phagosomal permeabilization and type I IFN production, key features of tuberculosis pathogenesis. The current model states that the secreted substrate ESAT-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::939ab839df337e899234c1380c34d17a
https://doi.org/10.1073/pnas.1911646117
https://doi.org/10.1073/pnas.1911646117
Autor:
Elsa Westerlund, Getachew Melkamu Aemero, Michael R. Wessels, M. Pontus A. Orning, Jenny L. Persson, Egil Lien, Benedicte Bastiat-Sempe, Dora Hancz, Christine Valfridsson
Publikováno v:
Journal of Innate Immunity
Group A Streptococcus (GAS) is a common and versatile human pathogen causing a variety of diseases. One of the many virulence factors of GAS is the secreted pore-forming cytotoxin streptolysin O (SLO), which has been ascribed multiple properties, inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c453848f10cd50c65d6eb04e247504de
https://doi.org/10.1159/000496403
https://doi.org/10.1159/000496403
Autor:
Julia, Lienard, Esther, Nobs, Victoria, Lovins, Elin, Movert, Christine, Valfridsson, Fredric, Carlsson
Publikováno v:
Proc Natl Acad Sci U S A
Following mycobacterial entry into macrophages the ESX-1 type VII secretion system promotes phagosomal permeabilization and type I IFN production, key features of tuberculosis pathogenesis. The current model states that the secreted substrate ESAT-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::920406c5b4fba910c0c1d140186548cb
https://pubmed.ncbi.nlm.nih.gov/31879349
https://pubmed.ncbi.nlm.nih.gov/31879349
Autor:
Oskar Olsson, Taye Tolera Balcha, Christine Valfridsson, Habtamu Yeba, Sten Skogmar, Marianne Jansson, Daba Mulleta, Per Björkman, Fredric Carlsson
Publikováno v:
Open Forum Infectious Diseases
Background Diagnosis of tuberculosis (TB) in human immunodeficiency virus (HIV)-coinfected individuals is challenging. We hypothesized that combinations of inflammatory markers could facilitate identification of active TB in HIV-positive individuals.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e5aa48f1e49f7e3f39b0c6315772758
http://europepmc.org/articles/PMC6379652
http://europepmc.org/articles/PMC6379652