Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Christine, Métin"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Directed cell migration requires sustained cell polarisation. In migrating cortical interneurons, nuclear movements are directed towards the centrosome that organises the primary cilium signalling hub. Primary cilium-elicited signalling, and
Externí odkaz:
https://doaj.org/article/48008bb414874d9989f5a4ece69697e5
Autor:
Christine Métin, Julie Stoufflet, Isabelle Caillé, Alain Trembleau, Coralie Fouquet, Sylvie Schneider-Maunoury, Mohamed Doulazmi, Pierre Vincent, Maxime Chaulet, Caroline Dubacq
Publikováno v:
Science Advances
Science Advances, 2020, 6 (36), ⟨10.1126/sciadv.aba3992⟩
Science Advances, American Association for the Advancement of Science (AAAS), 2020, 6 (36), ⟨10.1126/sciadv.aba3992⟩
Science Advances, 2020, 6 (36), ⟨10.1126/sciadv.aba3992⟩
Science Advances, American Association for the Advancement of Science (AAAS), 2020, 6 (36), ⟨10.1126/sciadv.aba3992⟩
The primary cilium regulates neuronal migration via cyclic AMP production activating protein kinase A at the centrosome.
The primary cilium (PC) is a small centrosome-assembled organelle, protruding from the surface of most eukaryotic cells. It
The primary cilium (PC) is a small centrosome-assembled organelle, protruding from the surface of most eukaryotic cells. It
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9617763c5f768c89ed5cf1a15ba6a99
http://europepmc.org/articles/PMC7467704
http://europepmc.org/articles/PMC7467704
Autor:
Jean-Vianney Barnier, Robert S. Adelstein, Justine Masson, Lucie Viou, Pierre Launay, Véronique Rousseau, Zhengping Jia, Clarisse Pace, Fujio Murakami, Xuefei Ma, Christine Métin
SUMMARYDuring the embryonic development, cortical interneurons migrate a long distance tangentially and then re-orient radially to settle in the cortical plate where they contribute to cortical circuits. Migrating interneurons express PAK3, a p21-act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49ebd9e4af920fe21585ee98fe0ae6fb
https://doi.org/10.1101/2020.07.06.168179
https://doi.org/10.1101/2020.07.06.168179
Autor:
Marika Nosten-Bertrand, Caroline Kappeler, Céline Dinocourt, Cécile Denis, Johanne Germain, Françoise Phan Dinh Tuy, Soraya Verstraeten, Chantal Alvarez, Christine Métin, Jamel Chelly, Bruno Giros, Richard Miles, Antoine Depaulis, Fiona Francis
Publikováno v:
PLoS ONE, Vol 3, Iss 6, p e2473 (2008)
Patients with Doublecortin (DCX) mutations have severe cortical malformations associated with mental retardation and epilepsy. Dcx knockout (KO) mice show no major isocortical abnormalities, but have discrete hippocampal defects. We questioned the fu
Externí odkaz:
https://doaj.org/article/aff3bab36c654b1b90feacad4d89878a
Autor:
Christine Métin, Caroline Dubacq, Julie Stoufflet, Pierre Vincent, Coralie Fouquet, Alain Trembleau, Maxime Chaulet, Mohamed Doulazmi, Isabelle Caillé
The primary cilium (PC) is a small centrosome-assembled organelle, protruding from the surface of most eukaryotic cells. It plays a key role in cell migration, but the underlying mechanisms are unknown. Here, we show that the PC regulates neuronal mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db0136c58f700b7c3ca6b32a1768c8e3
Publikováno v:
Biomaterials
Biomaterials, 2019, 214, pp.119194. ⟨10.1016/j.biomaterials.2019.05.005⟩
Biomaterials, Elsevier, 2019, 214, pp.119194. ⟨10.1016/j.biomaterials.2019.05.005⟩
Biomaterials, 2019, 214, pp.119194. ⟨10.1016/j.biomaterials.2019.05.005⟩
Biomaterials, Elsevier, 2019, 214, pp.119194. ⟨10.1016/j.biomaterials.2019.05.005⟩
International audience; In mammalian embryos, cortical interneurons travel long distances among complex three-dimensional tissues before integrating into cortical circuits. Several molecular guiding cues involved in this migration process have been i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5347165d6bf92b7f0678a608bcdffbc1
https://doi.org/10.1016/j.biomaterials.2019.05.005
https://doi.org/10.1016/j.biomaterials.2019.05.005
Autor:
Claire, Leclech, Christine, Métin
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1749
In the developing brain, MGE-derived interneuron precursors migrate tangentially long distances to reach the cortex in which they later establish connections with the principal cortical cells to control the activity of adult cortical circuits. Intern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37659ce1822fb7018b5474369089e977
https://pubmed.ncbi.nlm.nih.gov/29525996
https://pubmed.ncbi.nlm.nih.gov/29525996
Autor:
Martin Catala, Bénédicte Durand, Marie Paschaki, Christine Laclef, Laurianne Besse, Isabelle Anselme, Aurélien Palmyre, Sylvie Schneider-Maunoury, Christine Métin, Maria Pedraza, Dominique Baas
Publikováno v:
Human Molecular Genetics
Human Molecular Genetics, Oxford University Press (OUP), 2015, 24 (17), pp.4997-5014. ⟨10.1093/hmg/ddv221⟩
Human Molecular Genetics, 2015, 24 (17), pp.4997-5014. ⟨10.1093/hmg/ddv221⟩
Human Molecular Genetics, Oxford University Press (OUP), 2015, 24 (17), pp.4997-5014. ⟨10.1093/hmg/ddv221⟩
Human Molecular Genetics, 2015, 24 (17), pp.4997-5014. ⟨10.1093/hmg/ddv221⟩
International audience; Agenesis of the corpus callosum (AgCC) is a frequent brain disorder found in over 80 human congenital syndromes including ciliopathies. Here, we report a severe AgCC in Ftm/Rpgrip1l knockout mouse, which provides a valuable mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeda4c7b5ca61dde23eff7b0abc80262
https://doi.org/10.1093/hmg/ddv221
https://doi.org/10.1093/hmg/ddv221
Autor:
Christine Laclef, Christine Métin
Publikováno v:
Seminars in Cell and Developmental Biology
Seminars in Cell and Developmental Biology, Elsevier, 2017, ⟨10.1016/j.semcdb.2017.09.017⟩
Seminars in Cell and Developmental Biology, 2017, ⟨10.1016/j.semcdb.2017.09.017⟩
Seminars in Cell and Developmental Biology, Elsevier, 2017, ⟨10.1016/j.semcdb.2017.09.017⟩
Seminars in Cell and Developmental Biology, 2017, ⟨10.1016/j.semcdb.2017.09.017⟩
International audience; This review will focus on early aspects of cortical interneurons (cIN) development from specification to migration and final positioning in the human cerebral cortex. These mechanisms have been largely studied in the mouse mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c23206434cdfbca16ec68ed8a3aa2fd
https://hal.sorbonne-universite.fr/hal-01618849
https://hal.sorbonne-universite.fr/hal-01618849
Autor:
Christine Métin
Publikováno v:
médecine/sciences. 30:991-995
Dans un article fondateur paru en 1977, G. Albrecht-Buehler decrivait un cil primaire a la surface de fibroblastes en migration, et remarquait que le cil est oriente parallelement a la direction de migration des cellules. La presence d’un cil prima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8fdb07de435465c4ec2b2d1da7b40b4
https://doi.org/10.1051/medsci/20143011013
https://doi.org/10.1051/medsci/20143011013