Regulatory interplay between Vav1, Syk and β-catenin occurs in lung cancer cells

Autor: Vanessa Laurienté, Antonin Oudar, Christine Le Roy, Lionel Guittat, Souleymane Harouna-Rachidi, Laura Gardano, Rofia Boudria, Nadine Varin-Blank, Elisabetta Dondi

Publikováno v: Cellular signalling. 86

Vav1 exhibits two signal transducing properties as an adaptor protein and a regulator of cytoskeleton organization through its Guanine nucleotide Exchange Factor module. Although the expression of Vav1 is restricted to the hematopoietic lineage, its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ca77eeb17d5bf51084fa0acc4dfcb7
https://pubmed.ncbi.nlm.nih.gov/34252536

Protein kinase D-dependent CXCR4 down-regulation upon BCR triggering is linked to lymphadenopathy in chronic lymphocytic leukaemia

Autor: Maude Quettier, Dominique Ledoux, Christine Le Roy, Marouane Bouyaba, Stéphanie Le Coquil, Vincent Levy, Lionel Guittat, Nadine Varin-Blank, Stéphane Saint-Georges, Florence Ajchenbaum-Cymbalista, Vanessa Laurienté

Publikováno v: Oncotarget
Oncotarget, Impact journals, 2016, 7 (27), ⟨10.18632/oncotarget.9031⟩

// Stephane Saint-Georges 1,2 , Maude Quettier 1,2 , Marouane Bouyaba 3 , Stephanie Le Coquil 1,2 , Vanessa Lauriente 1,2 , Lionel Guittat 1,2 , Vincent Levy 3 , Florence Ajchenbaum-Cymbalista 1,2,4 , Nadine Varin-Blank 1,2 , Christine Le Roy 1,2,* a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbbf616009d19fb98ab47a8ebbfa2162
https://doi.org/10.18632/oncotarget.9031

Old DAT and new data: Positive direct antiglobulin test identifies a subgroup with poor outcome among chronic lymphocytic leukemia stage A patients

Autor: Anne Quinquenel, Nadine Varin-Blank, Vincent Levy, Chadi Al Nawakil, Fanny Baran-Marszak, Virginie Eclache, Christine Le Roy, Florence Ajchenbaum-Cymbalista, Rémi Letestu, Alain Delmer, Mohammed Khalloufi, Marouane Boubaya

Publikováno v: American Journal of Hematology. 90:E5-E8

Only a minority of chronic lymphocytic leukemia (CLL) patients harboring a positive direct antiglobulin test (DAT) will develop autoimmune hemolytic anemia (AIHA). In a single institution cohort of 378 CLL patients, 56 patients (14.8%) had at least o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6da6072106dea654a6b140f62706a475
https://doi.org/10.1002/ajh.23861

The degree of BCR and NFAT activation predicts clinical outcomes in chronic lymphocytic leukemia

Autor: Rémi Letestu, Marouane Boubaya, Virginie Eclache, Christine Le Roy, Florence Ajchenbaum-Cymbalista, Nadine Varin-Blank, Pierre-Antoine Deglesne, Vincent Levy, Taoufik Beitar, Nathalie Chevallier, Maude Quettier

Publikováno v: Blood. 120:356-365

B-cell antigen receptor (BCR)–mediated signaling plays a critical role in chronic lymphocytic leukemia (CLL) pathogenesis and gives an in vitro survival advantage to B cells isolated from patients with unfavorable prognostic factors. In this study,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65bd6b77bc0d9b9f226ebb9ac273fce3
https://doi.org/10.1182/blood-2011-12-397158

Mixed μ-phosphido or μ-thiolato μ-halo-dimolybdenum(III) compounds [Mo2Cp2(μ-SMe)2(μ-X)(μ-Y)] (X=PPh2, Y=Cl; X=SCH3, Y=Br, I): Electrochemical and structural comparisons – The X-ray structure of [{Mo2Cp2Br(μ-O)(μ-SMe)2}2(μ-MoO4)]

Autor: François Y. Pétillon, Jean Talarmin, Philippe Schollhammer, Christine Le Roy, Kenneth W. Muir

Publikováno v: Journal of Organometallic Chemistry
Journal of Organometallic Chemistry, Elsevier, 2006, 691 (5), pp.898-906. ⟨10.1016/j.jorganchem.2005.10.033⟩

Mixed μ-phosphido or μ-thiolato μ-halo-dimolybdenum(III) compounds [Mo 2 Cp 2 (μ-SMe) 2 (μ-X)(μ-Y)] (X = PPh 2 , Y = Cl ( 1 ); X = SCH 3 , Y = Br ( 3 ), I( 4 )) have been studied. Syntheses and X-ray structures of the new bromo and iodo analogu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4dfa4199ac3f755f24151dc3e6220e8
https://doi.org/10.1016/j.jorganchem.2005.10.033