Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Christine, Lair"'
Autor:
Jidong Zhang, Christine Lair, Christine Roubert, Kwame Amaning, María Belén Barrio, Yannick Benedetti, Zhicheng Cui, Zhongliang Xing, Xiaojun Li, Scott G. Franzblau, Nicolas Baurin, Florence Bordon-Pallier, Cathy Cantalloube, Stephanie Sans, Sandra Silve, Isabelle Blanc, Laurent Fraisse, Alexey Rak, Lasse B. Jenner, Gulnara Yusupova, Marat Yusupov, Junjie Zhang, Takushi Kaneko, T.J. Yang, Nader Fotouhi, Eric Nuermberger, Sandeep Tyagi, Fabrice Betoudji, Anna Upton, James C. Sacchettini, Sophie Lagrange
Publikováno v:
Cell. 186:1013-1025.e24
Autor:
Eric L. Nuermberger, Michel Geslin, Nicole C. Ammerman, Evelyne Fontaine, Florence Bordon-Pallier, Holger Hoffmann, Peer Lukat, Nestor Zaburannyi, Mark Brönstrup, Rolf Müller, Hans Matter, Dirk W. Heinz, Sandeep Tyagi, Sylvie Sordello, Armin Bauer, Michael Kurz, Kai Borchers, Sylvie Klieber, Courtemanche Gilles, Jacques H. Grosset, Silke C. Wenzel, Markus Kohlmann, Angela Kling, Christine Lair, María Belén Barrio, Jennifer Herrmann, Sophie Lagrange, Deepak V. Almeida, Laurent Fraisse, Claudia König, Martin Gerlitz, Peter Hammann
Publikováno v:
Science. 348:1106-1112
New for old—TB drug development Tuberculosis (TB) is a global health threat for which there is only lengthy drug treatment. Patients need to consume multiple tablets over several months and frequently fail to complete their treatment. Consequently,
Autor:
Jerome Menegotto, Cédric Couturier, Anna M. Upton, Christine Lair, Eric Bacqué, Sophie Lagrange, Armin Bauer, Takushi Kaneko, Bodo Scheiper, Eric Cogo, Corinne Perron, Alain Pellet
Publikováno v:
Bioorganicmedicinal chemistry letters. 26(21)
A high throughput phenotypic screening against Mycobacterium smegmatis led us to the discovery of a new class of bacteriostatic, highly hydrophobic antitubercular quinazolinones that potently inhibited the in vitro growth of either extracellular or i
Autor:
Angela, Kling, Peer, Lukat, Deepak V, Almeida, Armin, Bauer, Evelyne, Fontaine, Sylvie, Sordello, Nestor, Zaburannyi, Jennifer, Herrmann, Silke C, Wenzel, Claudia, König, Nicole C, Ammerman, María Belén, Barrio, Kai, Borchers, Florence, Bordon-Pallier, Mark, Brönstrup, Gilles, Courtemanche, Martin, Gerlitz, Michel, Geslin, Peter, Hammann, Dirk W, Heinz, Holger, Hoffmann, Sylvie, Klieber, Markus, Kohlmann, Michael, Kurz, Christine, Lair, Hans, Matter, Eric, Nuermberger, Sandeep, Tyagi, Laurent, Fraisse, Jacques H, Grosset, Sophie, Lagrange, Rolf, Müller
Publikováno v:
Science (New York, N.Y.). 348(6239)
The discovery of Streptomyces-produced streptomycin founded the age of tuberculosis therapy. Despite the subsequent development of a curative regimen for this disease, tuberculosis remains a worldwide problem, and the emergence of multidrug-resistant
Autor:
Régis Steinberg, Jean-Pierre Maffrand, Pierre Roger, Georgette Gout, Philippe Soubrie, Evelyne Fontaine, Christine Lair, Danielle Gully, Marc Pascal, Valerie Darre, Michel Geslin, Jacques Simiand, Gérard Le Fur, Rebecca M. Pruss, Pierre-Eric Rouby, Bernard Scatton, Laurence Serva, Josette Guitard, Claudine Marcy, D. Rodier, Guy Griebel
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 301:322-332
4-(2-Chloro-4-methoxy-5-methylphenyl)- N -[(1 S )-2-cyclopropyl-1- (3-fluoro-4-methylphenyl)ethyl]5-methyl- N -(2-propynyl)-1,3-thiazol-2-amine hydrochloride (SSR125543A), a new 2-aminothiazole derivative, shows nanomolar affinity for human cloned or
Autor:
Martial Ruat, Christine Lair, Danielle Gully, Bruno Chatel, Jean-Pierre Maffrand, Robert H. Dodd, Sandrine Ferry
Publikováno v:
Biochemical and Biophysical Research Communications. 238:866-873
The calcium sensing receptor (CaSR), a member of the G-protein coupled receptor family, is expressed on a variety of cell types and responds to extracellular calcium. We have characterized pharmacological properties of (+/-)NPS 568, a calcimimetic, t
Autor:
Danielle, Gully, Michel, Geslin, Laurence, Serva, Evelyne, Fontaine, Pierre, Roger, Christine, Lair, Valerie, Darre, Claudine, Marcy, Pierre-Eric, Rouby, Jacques, Simiand, Josette, Guitard, Georgette, Gout, Regis, Steinberg, Daniel, Rodier, Guy, Griebel, Philippe, Soubrie, Marc, Pascal, Rebecca, Pruss, Bernard, Scatton, Jean-Pierre, Maffrand, Gerard, Le Fur
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 301(1)
4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1- (3-fluoro-4-methylphenyl)ethyl]5-methyl-N-(2-propynyl)-1,3-thiazol-2-amine hydrochloride (SSR125543A), a new 2-aminothiazole derivative, shows nanomolar affinity for human cloned or nativ