Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Christine, Hofmann"'
Autor:
Marius Vogt, Hermann Girschick, Tilmann Schweitzer, Clemens Benoit, Annette Holl-Wieden, Lothar Seefried, Franz Jakob, Christine Hofmann
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-10 (2020)
Abstract Background Hypophosphatasia (HPP) is a rare, inherited metabolic disorder caused by loss-of-function mutations in the ALPL gene that encodes the tissue-nonspecific alkaline phosphatase TNAP (ORPHA 436). Its clinical presentation is highly he
Externí odkaz:
https://doaj.org/article/4e46608f0c36461cb5ae8368910ee29b
Publikováno v:
Arthritis und Rheuma. 43:113-119
ZUSAMMENFASSUNGDie Hypophosphatasie (HPP) ist eine seltene genetische Erkrankung, welche infolge einer verminderten Alkalischen Phosphatase-Aktivität zu Problemen an Knochen, Muskeln, Zähnen, aber auch zahlreichen weiteren Organsystemen führen kan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cc7385d6f1136bf1e4f8ee4a171b5e0
https://doi.org/10.1055/a-2009-9454
https://doi.org/10.1055/a-2009-9454
Autor:
Johannes Dirks, Jonas Fischer, Gabriele Haase, Annette Holl-Wieden, Christine Hofmann, Hermann Girschick, Henner Morbach
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Juvenile idiopathic arthritis (JIA) encompasses a heterogeneous group of diseases. The appearance of antinuclear antibodies (ANAs) in almost half of the patients suggests B cell dysregulation as a distinct pathomechanism in these patients. Additional
Externí odkaz:
https://doaj.org/article/93339a7e9a4b456c96da6b1b43789cce
Publikováno v:
Biomolecules, Vol 10, Iss 12, p 1648 (2020)
Tissue-nonspecific alkaline phosphatase (TNAP) is a ubiquitously expressed enzyme that is best known for its role during mineralization processes in bones and skeleton. The enzyme metabolizes phosphate compounds like inorganic pyrophosphate and pyrid
Externí odkaz:
https://doaj.org/article/9ee5f5f5444e4188ac353581a1ac7f92
Autor:
Hermann J. Girschick, Henner Morbach, Julia Klaussner, Johannes Dirks, Stephan Hackenberg, Jonas Fischer, Gabriele Haase, Annette Holl-Wieden, Christine Hofmann
Publikováno v:
Arthritis & Rheumatology. 74:150-162
Objectives Antinuclear antibody (ANA) positive Juvenile Idiopathic Arthritis (JIA) is characterized by synovial B cell hyperactivity, but the precise role of CD4+ T cells in promoting local B cell activation is unknown. The objective of this study is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5d66280c3cdce2e962e4a9388479d4a
https://doi.org/10.1002/art.41913
https://doi.org/10.1002/art.41913
Autor:
Julia Nentwich, Katharina Ruf, Hermann Girschick, Annette Holl-Wieden, Henner Morbach, Helge Hebestreit, Christine Hofmann
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 18, Iss 1, Pp 1-1 (2020)
Following publication of the original article [1], we have been notified that the authors’ first names and last names are presented in wrong order. The presentation of names, thus, should be as follows:
Externí odkaz:
https://doaj.org/article/627baaf3fb5041c9a970c9af9296a493
Publikováno v:
Osteologie. 29:275-282
ZusammenfassungDie Hypophosphatasie (HPP) als Folge einer genetisch bedingt defizienten Aktivität der gewebeunspezifischen alkalischen Phosphatase (TNAP) ist geprägt durch ein ausgesprochen weites Spektrum möglicher Manifestationen, sowohl hinsich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3320afb4b57bd6c204eb06117fadb39f
https://doi.org/10.1055/a-1257-7976
https://doi.org/10.1055/a-1257-7976
Autor:
Christine Hofmann, Maria Luisa Bianchi, Franz Jakob, Nick Bishop, Núria Guañabens, M. C. Zillikens, Christian Roux
Publikováno v:
Osteoporosis International, 31(8), 1445-1460. Springer London
This article provides an overview of the current knowledge on hypophosphatasia—a rare genetic disease of very variable presentation and severity—with a special focus on adolescents and adults. It summarizes the available information on the many k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55fdbe4989ed69c0a397467402c3b130
https://doi.org/10.1007/s00198-020-05345-9
https://doi.org/10.1007/s00198-020-05345-9
This paper undertakes a meta study on informal apprenticeship in developing countries. It compares the findings of country-level research conducted by the ILO and others in the past 15 years to shed more light on apprenticeship systems in the informa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36964f07165f007b692b965cdaa182e4
https://doi.org/10.54394/wjek5468
https://doi.org/10.54394/wjek5468
Autor:
Jonas, Fischer, Johannes, Dirks, Julia, Klaussner, Gabriele, Haase, Annette, Holl-Wieden, Christine, Hofmann, Stephan, Hackenberg, Hermann, Girschick, Henner, Morbach
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.)REFERENCES. 74(1)
Antinuclear antibody (ANA)-positive juvenile idiopathic arthritis (JIA) is characterized by synovial B cell hyperactivity, but the precise role of CD4+ T cells in promoting local B cell activation is unknown. This study was undertaken to determine th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8503fd0eaf0866a55430357fcaa4d39f
https://pubmed.ncbi.nlm.nih.gov/34196496
https://pubmed.ncbi.nlm.nih.gov/34196496