Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Christine, Halske"'
Autor:
Christoph Röcken, Anu Amallraja, Christine Halske, Luka Opasic, Arne Traulsen, Hans-Michael Behrens, Sandra Krüger, Anne Liu, Jochen Haag, Jan-Hendrik Egberts, Philip Rosenstiel, Tobias Meißner
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-19 (2021)
Abstract Background Cancer is a somatic evolutionary disease and adenocarcinomas of the stomach and gastroesophageal junction (GC) may serve as a two-dimensional model of cancer expansion, in which tumor subclones are not evenly mixed during tumor pr
Externí odkaz:
https://doaj.org/article/fd8df01746ac4a9f8e7885c8e7424eff
Autor:
Hauke Schoop, Anna Bregenzer, Christine Halske, Hans-Michael Behrens, Sandra Krüger, Jan-Hendrik Egberts, Christoph Röcken
Publikováno v:
Translational Oncology, Vol 13, Iss 2, Pp 165-176 (2020)
With recent studies uncovering the complex landscape of immune checkpoint regulators in gastric cancer (GC), we aimed to characterize the expression of the checkpoint proteins V-domain Ig suppressor of T-cell activation (VISTA), programmed cell death
Externí odkaz:
https://doaj.org/article/c57ce13de0704d639a3436c97ff83b53
Autor:
Wiebke Siemsen, Christine Halske, Hans-Michael Behrens, Sandra Krüger, Christoph Becker-Pauly, Christoph Röcken
Publikováno v:
Gastric Cancer.
Background The gastric microbiome and inflammation play a key role in gastric cancer (GC) by regulating the immune response in a complex manner and by inflammatory events supporting carcinogenesis. Meprin β is a zinc endopeptidase and participates i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cabd1149306c81cf4384f57b3fe2480
https://doi.org/10.1007/s10120-023-01385-2
https://doi.org/10.1007/s10120-023-01385-2
Autor:
Christian Röder, Sandra Krüger, Christine Halske, Anna Trauzold, Jan-Paul Gundlach, Anna Willms, Franka Maria Schlegel, Holger Kalthoff, Charlotte Hauser, Thomas E. Becker, Christoph Röcken
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Purpose HMGA2 has frequently been found in benign as well as malignant tumors and a significant association between HMGA2 overexpression and poor survival in different malignancies was described. In pancreatic ductal adenocarcinoma (PDAC), nuclear HM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8fd2f698509d4eb7f5f57844fb0994
http://europepmc.org/articles/PMC8484217
http://europepmc.org/articles/PMC8484217
Autor:
Christine Halske
Publikováno v:
Der Pathologe. 41:76-82
Magenkarzinome messen bei der Erstdiagnose haufig mehr als 5 cm. Sowohl die Diagnostik als auch die Biomarkertestung fur eine zielgerichtete Tumortherapie wird in der Regel jedoch an wenigen Millimetern messendem Biopsiematerial durchgefuhrt, welches
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9f059c812e0ee93b921d40c2132cbd0
https://doi.org/10.1007/s00292-020-00881-x
https://doi.org/10.1007/s00292-020-00881-x
Autor:
Anna Bregenzer, Jan-Hendrik Egberts, Sandra Krüger, Christine Halske, Hans-Michael Behrens, Hauke Schoop, Christoph Röcken
Publikováno v:
Translational Oncology, Vol 13, Iss 2, Pp 165-176 (2020)
Translational Oncology
Translational Oncology
With recent studies uncovering the complex landscape of immune checkpoint regulators in gastric cancer (GC), we aimed to characterize the expression of the checkpoint proteins V-domain Ig suppressor of T-cell activation (VISTA), programmed cell death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c43d6ad980133b79f5f7ea8125465c90
http://www.sciencedirect.com/science/article/pii/S1936523319303043
http://www.sciencedirect.com/science/article/pii/S1936523319303043
Autor:
Jan-Hendrik Egberts, Christine Halske, Tobias Meissner, Arne Traulsen, Anu Amallraja, Hans-Michael Behrens, Philip Rosenstiel, Luka Opasic, Anne Liu, Christoph Röcken, Jochen Haag, Sandra Krüger
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-19 (2021)
Genome Medicine
Genome Medicine
Background Cancer is a somatic evolutionary disease and adenocarcinomas of the stomach and gastroesophageal junction (GC) may serve as a two-dimensional model of cancer expansion, in which tumor subclones are not evenly mixed during tumor progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f79abf22f9d520fbd9bc38a7b27a7e60
https://doi.org/10.1186/s13073-021-00975-y
https://doi.org/10.1186/s13073-021-00975-y
Autor:
Hans-Michael Behrens, Christine Halske, Matthias Dottermusch, Christoph Röcken, Sandra Krüger
Publikováno v:
Virchows Archiv
Gastric cancer (GC) is frequently diagnosed and treated in advanced tumour stages with poor prognosis. Recent studies have identified isoform 2 of the tight junction protein claudin-18 (CLDN18.2) as a promising target in GC therapy. In this study, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc186d8f511eb0d341665a59c57251d1
https://doi.org/10.1007/s00428-019-02624-7
https://doi.org/10.1007/s00428-019-02624-7
Autor:
Jan-Paul Gundlach, Jannik Kerber, Alexander Hendricks, Alexander Bernsmeier, Christine Halske, Christian Röder, Thomas Becker, Christoph Röcken, Felix Braun, Susanne Sebens, Nils Heits
Publikováno v:
Journal of Clinical Medicine; Volume 11; Issue 10; Pages: 2785
Although the Mitogen-activated protein kinase (MAPK) pathway is enriched in cholangiocarcinoma (CCA), treatment with the multityrosine kinase-inhibitor Sorafenib is disappointing. While cancer-associated fibroblasts (CAF) are known to contribute to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fdc24079cc6c893d8e672e2acbb622d
https://doi.org/10.3390/jcm11102785
https://doi.org/10.3390/jcm11102785
Autor:
Christine, Halske
Publikováno v:
Der PathologeLiteratur. 41(Suppl 2)
Gastric carcinomas often measure more than 5 cm at primary diagnosis. Predictive biomarker testing is usually carried out on tissue biopsies, which do not represent the entire tumor biology and intratumoral heterogeneity.The aim of this study was to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e1ccbacf586160436346371462fabeb
https://pubmed.ncbi.nlm.nih.gov/33427920
https://pubmed.ncbi.nlm.nih.gov/33427920