Cytokine profile of anti-spike CD4+T cells predicts humoral and CD8+T cell responses after anti-SARS-CoV-2 mRNA vaccination

Autor: Nadine Benhamouda, Anissa Besbes, Rebecca Bauer, Nesrine Mabrouk, Gauthier Gadouas, Corinne Desaint, Lucie Chevrier, Maeva Lefebvre, Anne Radenne, Marie Roelens, Béatrice Parfait, Daniela Weiskopf, Alessandro Sette, Nadège Gruel, Marie Courbebaisse, Victor Appay, Stephane Paul, Guy Gorochov, Jacques Ropers, Said Lebbah, Jean-Daniel Lelievre, Ludger Johannes, Jonathan Ulmer, David Lebeaux, Gerard Friedlander, Xavier De Lamballerie, Patrice Ravel, Marie Paule Kieny, Fréderic Batteux, Christine Durier, Odile Launay, Eric Tartour

Publikováno v: iScience, Vol 27, Iss 8, Pp 110441- (2024)

Summary: Coordinating immune responses – humoral and cellular – is vital for protection against severe Covid-19. Our study evaluates a multicytokine CD4+T cell signature’s predictive for post-vaccinal serological and CD8+T cell responses. A cyt

Externí odkaz: https://doaj.org/article/bae9b74a735344409d5106899f8ed864

Brand-specific estimates of influenza vaccine effectiveness for the 2021–2022 season in Europe: results from the DRIVE multi-stakeholder study platform

Autor: Anke L. Stuurman, Antonio Carmona, Jorne Biccler, Alexandre Descamps, Miriam Levi, Ulrike Baum, Ainara Mira-Iglesias, Stefania Bellino, Uy Hoang, Simon de Lusignan, Roberto Bonaiuti, Bruno Lina, Caterina Rizzo, Hanna Nohynek, Javier Díez-Domingo, DRIVE Study Contributors, Anca Cristina Drăgănescu, Oana Săndulescu, Daniela Piţigoi, Victor Daniel Miron, Anca Streinu-Cercel, Anuţa Bilaşco, Adrian Streinu-Cercel, Dragoş Florea, Ovidiu Vlaicu, Simona Paraschiv, Leontina Bănică, Dan Oţelea, Monika Redlberger-Fritz, Eva Geringer, Amparo López-Bernus, Ana Haro Perez, Nieves Gutierrez Zufiaurre, Cristina Carbonell Muñoz, Miguel Marcos Martin, Muñoz Juan Luis Bellido, Isabel Gil Rodríguez, Antonio Muro Alvarez, Moncef Belhassen Garcia, Giancarlo Icardi, Stefano Mosca, Donatella Panatto, Emanuele Montomoli, Silvana Castaldi, Andrea Orsi, Alexander Domnich, Maria Chironna, Daniela Loconsole, Ilaria Manini, Christian Napoli, Alessandra Torsello, Elena Pariani, and Piero Luigi Lai, Susana Otero-Romero, Andrés Antón Pagarolas, Cristina Andrés, Ingrid Carbonés, Oleguer Pares, Mar Fornaguera, Anna Oller, Xavier Salgado, Patricia Tejerina, Cristina Martinez, Alejandro Orrico-Sánchez, F. Xavier López-Labrador, Beatriz Mengual-Chuliá, Judit Sánchez Soler, María Jinglei Casanova Palomino, Juan Mollar-Maseres, Miguel Tortajada-Girbés, Noelia Rodríguez-Blanco, Mario Carballido-Fernández, Raquel Andreu Ivorra, Àngels Sierra Fortuny, Beatriz Segura Segura, Cristina Mingot Ureta, Sagrario Corrales Díaz-Flores, Ángela Sánchez Pla, María Dolores Tirado Balaguer, Juan Alberola, José Miguel Nogueira, Juan J Camarena, Francisco Arjona-Zaragozí, Maruan Shalabi Benavent, José Luis López-Hontangas, María Dolores Gómez, Alejandro Martín-Quirós, Carlos Cañada Illana, Emilio Cendejas, Irma Casas García, Guillermo Mena Pinilla, María Esteve Pardo, Lola Álamo Junquera, Cristina Casañ, Sandra Fernandez Morodo, Agueda Hernández, Pere-Joan Cardona, Marta Segura, Andreu C. Pelegrin, Sara González-Gómez, Verónica Saludes, Elisa Martró, Valtýr Stefánsson Thors, Kristín L. Björnsdóttir, Liem Luong, Zineb Lesieur, Yacine Saidi, Rebecca Bauer, Christine Pereira, Philippe Vanhems, Fabrice Lainé, Florence Galtier, Xavier Duval, Christine Durier, Paolo Bonanni, Alfredo Vannacci, Claudia Ravaldi

Publikováno v: Frontiers in Public Health, Vol 11 (2023)

IntroductionDevelopment of Robust and Innovative Vaccine Effectiveness (DRIVE) was a European public–private partnership (PPP) that aimed to provide annual, brand-specific estimates of influenza vaccine effectiveness (IVE) for regulatory and public

Externí odkaz: https://doaj.org/article/75fb3f72a3704f36bf12c2869d3a6c12

Screening test for neutralizing antibodies against yellow fever virus, based on a flavivirus pseudotype.

Autor: Séverine Mercier-Delarue, Christine Durier, Nathalie Colin de Verdière, Jean-Dominique Poveda, Vincent Meiffrédy, Maria Dolores Fernandez Garcia, Stéphane Lastère, Raymond Césaire, Jean-Claude Manuggera, Jean-Michel Molina, Ali Amara, François Simon

Publikováno v: PLoS ONE, Vol 12, Iss 5, p e0177882 (2017)

Given the possibility of yellow fever virus reintroduction in epidemiologically receptive geographic areas, the risk of vaccine supply disruption is a serious issue. New strategies to reduce the doses of injected vaccines should be evaluated very car

Externí odkaz: https://doaj.org/article/a4c776ce34ff4abaa89c703ad3c1f5e3

A comparison of Sars-Cov-2 vaccine platforms: the CoviCompare project

Autor: Diana Molino, Christine Durier, Anne Radenne, Corinne Desaint, Jacques Ropers, Soizic Courcier, Louis Victorien Vieillard, Claire Rekacewicz, Beatrice Parfait, Victor Appay, Frédéric Batteux, Emmanuel Barillot, Michel Cogné, Béhazine Combadière, Christiane S. Eberhardt, Guy Gorochov, Philippe Hupé, Laetitia Ninove, Stéphane Paul, Isabelle Pellegrin, Sylvie van der Werf, Maeva Lefebvre, Elisabeth Botelho-Nevers, Inmaculada Ortega-Perez, Marie Jaspard, Samba Sow, Jean Daniel Lelièvre, Xavier de Lamballerie, Marie Paule Kieny, Eric Tartour, Odile Launay

Publikováno v: Nature Medicine
Nature Medicine, 2022, 28 (5), pp.882-884. ⟨10.1038/s41591-022-01785-4⟩
Nature Medicine, Nature Publishing Group, 2022, 28 (5), pp.882-884. ⟨10.1038/s41591-022-01785-4⟩

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94faaadbcfaece5cb4c4201489f82318
https://hal.science/hal-03693493

Vaccine effectiveness against COVID-19 hospitalization in adults in France: A test negative case control study

Autor: Liem Binh Luong Nguyen, Rebecca Bauer, Zineb Lesieur, Florence Galtier, Xavier Duval, Philippe Vanhems, Fabrice Lainé, Pierre Tattevin, Christine Durier, Odile Launay

Publikováno v: Infectious Diseases Now
Infectious Diseases Now, 2022, 52 (1), pp.40-43. ⟨10.1016/j.idnow.2021.12.002⟩
Infectious Diseases Now, Elsevier, 2022, ⟨10.1016/j.idnow.2021.12.002⟩

International audience; BACKGROUND: Measuring vaccine effectiveness (VE) using real-life data is critical to confirm the effectiveness of licensed vaccine, which could strengthen vaccination adherence. METHODS: We measured VE against adult COVID-19 h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb23ac1181104ff3b88dec00588fb0cf
https://hal.science/hal-03513927/document