Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Christine, Donsante"'
Publikováno v:
Neurobiology of Disease, Vol 125, Iss , Pp 115-122 (2019)
Trihexyphenidyl, a nonselective muscarinic receptor antagonist, is the small molecule drug of choice for the treatment of DYT1 dystonia, but it is poorly tolerated due to significant side effects. A better understanding of the mechanism of action of
Externí odkaz:
https://doaj.org/article/42e940c5e75b42f6aa93993af421d915
Publikováno v:
Neurobiol Dis
Neurobiology of Disease, Vol 125, Iss, Pp 115-122 (2019)
Neurobiology of Disease, Vol 125, Iss, Pp 115-122 (2019)
Trihexyphenidyl, a nonselective muscarinic receptor antagonist, is the small molecule drug of choice for the treatment of DYT1 dystonia, but it is poorly tolerated due to significant side effects. A better understanding of the mechanism of action of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fa0ace9aa7ced47d0a4790f1665bee9
https://doi.org/10.1016/j.nbd.2019.01.012
https://doi.org/10.1016/j.nbd.2019.01.012
Autor:
Ellen J. Hess, MariadeLourdes Tansey, Samuel J. Rose, Hyder A. Jinnah, Christine Donsante, Valerie Joers, Xueliang Fan, Porter Harrast
Publikováno v:
Movement Disorders. 32:1694-1700
Background Recent neuroimaging studies implicate nigrostriatal degeneration as a critical factor in producing late-onset parkinsonism in patients with l-dopa-responsive dystonia-causing mutations. However, postmortem anatomical studies do not reveal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ccf45888faba998b41e0b728bbecd50
https://doi.org/10.1002/mds.27169
https://doi.org/10.1002/mds.27169
Autor:
Xueliang Fan, Ellen J. Hess, Alec P. Shannon, Maria A. Briscione, Christine Donsante, Hyder A. Jinnah, Diane J. Sutcliffe, Anthony M. Downs, Tejas Sardar, David A. Gutman, Douglas Bernhard, Simone A. Campbell
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18735a9a467d2eac67d5457f9a25ecd1
https://doi.org/10.1096/fasebj.2018.32.1_supplement.827.14
https://doi.org/10.1096/fasebj.2018.32.1_supplement.827.14
Autor:
Samuel J, Rose, Porter, Harrast, Christine, Donsante, Xueliang, Fan, Valerie, Joers, Malú G, Tansey, H A, Jinnah, Ellen J, Hess
Publikováno v:
Movement disorders : official journal of the Movement Disorder Society. 32(12)
Recent neuroimaging studies implicate nigrostriatal degeneration as a critical factor in producing late-onset parkinsonism in patients with l-dopa-responsive dystonia-causing mutations. However, postmortem anatomical studies do not reveal neurodegene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e276e13722fdc8ad9545ba7b538604cc
https://pubmed.ncbi.nlm.nih.gov/28949038
https://pubmed.ncbi.nlm.nih.gov/28949038
Autor:
Marcus Watkins, Valerie S Salazar, Roberto Civitelli, Susan K. Grimston, Christine Donsante, Glenn L. Radice, Adriana Di Benedetto, Gabriel Mbalaviele
We have previously shown that targeted expression of a dominant-negative truncated form of N-cadherin (Cdh2) delays acquisition of peak bone mass in mice and retards osteoblast differentiation; whereas deletion of cadherin 11 (Cdh11), another osteobl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd11d10326d6c647eef374916422ff9c
https://europepmc.org/articles/PMC2908051/
https://europepmc.org/articles/PMC2908051/
Autor:
Christine Donsante, Marcus Watkins, Roberto Civitelli, Gabriel Mbalaviele, Glenn L. Radice, Su-Li Cheng, Chung Fang Lai
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 21(12)
Ovariectomy-induced bone loss is accentuated in mice with germline Cdh2 haploinsufficiency, the result of a decreased osteoblastogenesis in the face of normal osteoclast number. Reduced N-cadherin abundance in these mice decreases cell—cell adhesio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc0f8575da15763c2cf5b3424e6a513
https://pubmed.ncbi.nlm.nih.gov/17002573
https://pubmed.ncbi.nlm.nih.gov/17002573