Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Christina Y R, Tan"'
Autor:
Karen J. Gregory, Lauren T. May, Christina Y. R. Tan, Arthur Christopoulos, Paul J. White, Elizabeth A. Vecchio
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 357:36-44
Aberrant ligand-independent G protein-coupled receptor constitutive activity has been implicated in the pathophysiology of a number of cancers. The adenosine A2B receptor (A2BAR) is dynamically upregulated under pathologic conditions associated with
Autor:
Christina Y. R. Tan, James Ziogas, Alyson A. Miller, Paul J. White, Grant R Drummond, Christine E. Wright, Bevyn Jarrott, Kamani Rupika Subasinghe, Bich Anh Chau, W. Roy Jackson
Publikováno v:
MedChemComm. 6:634-639
Six derivatives containing mexiletine and its 2,6-dichloro analogue to which the potential antioxidant moiety isoindoline, its N-oxide and the N-hydroxy derivatives have been attached, have been evaluated as cardioprotective agents. Four of the deriv
Autor:
Masaaki, Sato, Bronwyn A, Evans, Anna L, Sandström, Ling Yeong, Chia, Saori, Mukaida, Bui San, Thai, Anh, Nguyen, Linzi, Lim, Christina Y R, Tan, Jo-Anne, Baltos, Paul J, White, Lauren T, May, Dana S, Hutchinson, Roger J, Summers, Tore, Bengtsson
Publikováno v:
Biochemical pharmacology. 148
The capacity of G protein-coupled receptors to modulate mechanistic target of rapamycin (mTOR) activity is a newly emerging paradigm with the potential to link cell surface receptors with cell survival. Cardiomyocyte viability is linked to signalling
Publikováno v:
Heart, Lung and Circulation. 24:S134