Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Christina Wodlej"'
1
Akademický článek
Optimization of ultrastructural preservation of human brain for transmission electron microscopy after long post-mortem intervals
Autor: Mariella Sele, Stefan Wernitznig, Saška Lipovšek, Snježana Radulović, Johannes Haybaeck, Anna Maria Birkl-Toeglhofer, Christina Wodlej, Florian Kleinegger, Stephan Sygulla, Marlene Leoni, Stefan Ropele, Gerd Leitinger
Publikováno v: Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-12 (2019)
Abstract Electron microscopy (EM) provides the necessary resolution to visualize the finer structures of nervous tissue morphology, which is important to understand healthy and pathological conditions in the brain. However, for the interpretation of
Externí odkaz: https://doaj.org/article/45c61f37eaf14e6da6db0071f314161f
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2
Akademický článek
Interaction of two antitumor peptides with membrane lipids - Influence of phosphatidylserine and cholesterol on specificity for melanoma cells.
Autor: Christina Wodlej, Sabrina Riedl, Beate Rinner, Regina Leber, Carina Drechsler, Dennis R Voelker, Jae-Yeon Choi, Karl Lohner, Dagmar Zweytick
Publikováno v: PLoS ONE, Vol 14, Iss 1, p e0211187 (2019)
R-DIM-P-LF11-322 and DIM-LF11-318, derived from the cationic human host defense peptide lactoferricin show antitumor activity against human melanoma. While R-DIM-P-LF11-322 interacts specifically with cancer cells, the non-specific DIM-LF11-318 exhib
Externí odkaz: https://doaj.org/article/d41f7d6a7a7542fd95a2a9bdcd0d92aa
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4
Eukaryotic translation initiation factor 6 overexpression plays a major role in the translational control of gallbladder cancer
Autor: Young Nyun Park, Ariane Aigelsreiter, Florian Kleinegger, Nicole Golob-Schwarzl, Margit Gogg-Kamerer, Michael Thalhammer, Johannes Haybaeck, Anna Maria Birkl-Toeglhofer, Christina Wodlej, Johannes Petzold
Publikováno v: Journal of Cancer Research and Clinical Oncology
Background Gallbladder cancer (GBC) is a rare neoplasia of the biliary tract with high mortality rates and poor prognosis. Signs and symptoms of GBC are not specific and often arise at late stage of disease. For this reason, diagnosis is typically ma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f896e70277d4d55657d3f6efed9ca780
https://doi.org/10.1007/s00432-019-03030-x
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5
Pharmacologic IL-6Rα inhibition in cholangiocarcinoma promotes cancer cell growth and survival
Autor: Johannes Haybaeck, Ariane Aigelsreiter, Harald Mangge, Eva Hofer, Peter Fickert, Alexander Stallinger, Young Nyun Park, Nicole Golob-Schwarzl, Florian Kleinegger, Stefanie Krassnig, Robert Reihs, Stefan Rose-John, Christoph Garbers, Anna Maria Birkl-Toeglhofer, Beate Rinner, Michael Thalhammer, Richard Moriggl, Anna Orlova, Sigurd Lax, Tobias Niedrist, Johannes Petzold, Christina Wodlej
Publikováno v: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1865:308-321
Biliary tract cancer (BTC) represents a malignant tumor of the biliary tract including cholangiocarcinoma (CCA) and the carcinoma of the gallbladder (GBC) with a 5-year survival rate between 5 and 18% due to late diagnosis and rapid disease progressi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c900987619458cf82e049010d28ebcbf
https://doi.org/10.1016/j.bbadis.2018.11.006
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6
An Unbiased Approach of Sampling TEM Sections in Neuroscience
Autor: Daniel Kummer, Johannes Haybäck, Christina Wodlej, Florian Reichmann, Christoph Birkl, Gerd Leitinger, Elisabeth Bock, Stefanie Krassnig, Florian Kleinegger, Mariella Sele, Anna Birkl-Töglhofer, Stefan Wernitznig, Peter Holzer
Publikováno v: Journal of Visualized Experiments.
Investigations of the ultrastructural features of neurons and their synapses are only possible with electron microscopy. Especially for comparative studies of the changes in densities and distributions of such features, an unbiased sampling protocol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f3094be8d375bde5a8c0eaf23d40c33
https://doi.org/10.3791/58745
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9
Human Lactoferricin Derived Peptides Induce Apoptosis Specifically in Cancer Cells through Targeting Membranous Phosphatidylserine
Autor: Beate Rinner, Dagmar Zweytick, Christina Wodlej, Karl Lohner, Helmut Schaider, Sabrina Riedl, Bernadette Liegl-Atzwanger
Publikováno v: Biophysical Journal. 112:185a
Cancer with poor prognosis and treatability, like glioblastoma or malignant melanoma demand for new effective treatment and is therefore a focus in our studies. Recently we were able to demonstrate that the negatively charged lipid phosphatidylserine
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::665011cc2eb07c7cee57f3b4aba53cb6
https://doi.org/10.1016/j.bpj.2016.11.1027
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