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pro vyhledávání: '"Christina Whitten-Bauer"'
Identification of Aquarius and Senataxin as Restriction Host Factors for Hepatitis B Virus Infection
Publikováno v:
Proceedings, Vol 50, Iss 1, p 2 (2020)
Hepatitis B virus (HBV) represents an important human pathogen causing acute and chronic hepatitis. Over 240 million people are chronically infected, many of whom will die due to complications such as liver cirrhosis and hepatocellular carcinoma. Cur
Externí odkaz:
https://doaj.org/article/a5f50d424aba4150842b8fa3f17acef1
Identification of Aquarius and Senataxin as Restriction Host Factors for Hepatitis B Virus Infection
Publikováno v:
Proceedings, Vol 50, Iss 2, p 2 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
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Digital.CSIC. Repositorio Institucional del CSIC
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© 2020 by the authors
Hepatitis B virus (HBV) represents an important human pathogen causing acute and chronic hepatitis. Over 240 million people are chronically infected, many of whom will die due to complications such as liver cirrhosis and h
Hepatitis B virus (HBV) represents an important human pathogen causing acute and chronic hepatitis. Over 240 million people are chronically infected, many of whom will die due to complications such as liver cirrhosis and h
Autor:
Christina Whitten-Bauer, Michael D. Huber, Larry Gerace, Urtzi Garaigorta, Andoni Gómez-Moreno, Pilar Gomollón-Zueco, Josan Chung
Publikováno v:
Cells
Volume 8
Issue 12
Digital.CSIC. Repositorio Institucional del CSIC
instname
Volume 8
Issue 12
Digital.CSIC. Repositorio Institucional del CSIC
instname
© 2019 by the authors.
Development of hepatitis C virus (HCV) infection cell culture systems has permitted the identification of cellular factors that regulate the HCV life cycle. Some of these cellular factors affect steps in the viral life cy
Development of hepatitis C virus (HCV) infection cell culture systems has permitted the identification of cellular factors that regulate the HCV life cycle. Some of these cellular factors affect steps in the viral life cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f91d49de40ba475d0d8c4d4dcda0d6db
http://hdl.handle.net/10261/197155
http://hdl.handle.net/10261/197155
Autor:
Zhongzhen Yi, Stephen Gottschalk, Christina Whitten-Bauer, Thomas Shum, Robert L. Kruse, Haruko Tashiro, Urtzi Garaigorta, Beatrice Bissig-Choisat, Xavier Legras, Mercedes Barzi, Karl-Dimiter Bissig
Publikováno v:
Cytotherapy. 20(5)
Background Chronic hepatitis B virus (HBV) infection remains incurable. Although HBsAg-specific chimeric antigen receptor (HBsAg-CAR) T cells have been generated, they have not been tested in animal models with authentic HBV infection. Methods We gen
Autor:
J C de la Torre, Nhi Ngo, Bryan Boyd, Stefan Wieland, Christina Whitten-Bauer, Francis V. Chisari, Kenji Takahashi
Publikováno v:
Journal of Virology. 88:752-757
We previously reported that exosomal transfer of hepatitis C virus (HCV) positive-strand RNA from human Huh-7 hepatoma cells to human plasmacytoid dendritic cells (pDCs) triggers pDC alpha/beta interferon (IFN-α/β) production in a Toll-like recepto
Publikováno v:
Proceedings of the National Academy of Sciences
Over 170 million people are chronically infected by the hepatitis C virus (HCV) and at risk for dying from liver cirrhosis and hepatocellular carcinoma. Current therapy is expensive, associated with significant side effects, and often ineffective. Di
Autor:
Melissa Carrillo, Michael L. McCaleb, Dacao Gao, Stefan Wieland, Christina Whitten-Bauer, Robert Hamatake, Urtzi Garaigorta, Eric E. Swayze, Gaetan Billioud, Robert L. Kruse, Zhi Hong, Leon Chen, Aneeza Kim, Jeffrey R. Crosby, Karl-Dimiter Bissig
Publikováno v:
Journal of hepatology. 64(4)
Background & Aims Current treatment of chronic hepatitis B virus infection (CHB) includes interferon and nucleos(t)ide analogues, which generally do not reduce HBV surface antigen (HBsAg) production, a constellation that is associated with poor progn
Autor:
Christina Whitten-Bauer, Stefan Wieland, Francis V. Chisari, Kelly A. Dryden, John L. Gerin, Mark Yeager
Publikováno v:
Molecular Cell. 22:843-850
Hepatitis B virus (HBV) infects more than 350 million people, of which one million will die every year. The infectious virion is an enveloped capsid containing the viral polymerase and double-stranded DNA genome. The structure of the capsid assembled
Autor:
Stefan Wieland, Francis V. Chisari, Marlène Dreux, Bryan Boyd, Urtzi Garaigorta, Elodie Décembre, Josan Chung, Christina Whitten-Bauer
Publikováno v:
Cell Host & Microbe
Cell Host & Microbe, 2012, 12 (4), pp.558-570. ⟨10.1016/j.chom.2012.08.010⟩
Cell Host & Microbe, 2012, 12 (4), pp.558-570. ⟨10.1016/j.chom.2012.08.010⟩
SummaryViral nucleic acids often trigger an innate immune response in infected cells. Many viruses, including hepatitis C virus (HCV), have evolved mechanisms to evade intracellular recognition. Nevertheless, HCV-permissive cells can trigger a viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a43d762791eb03d31194dc61add29abf
https://europepmc.org/articles/PMC3479672/
https://europepmc.org/articles/PMC3479672/
Autor:
Francis V. Chisari, Valery V. Fokin, K. Barry Sharpless, Pablo Gastaminza, Suresh M. Pitram, Marlène Dreux, Josan Chung, Jiajia Dong, Christina Whitten-Bauer, Larissa B. Krasnova
Publikováno v:
Journal of Virology
Journal of Virology, 2011, 85 (11), pp.5513-5523. ⟨10.1128/JVI.02116-10⟩
Journal of Virology, American Society for Microbiology, 2011, 85 (11), pp.5513-5523. ⟨10.1128/JVI.02116-10⟩
Journal of Virology, 2011, 85 (11), pp.5513-5523. ⟨10.1128/JVI.02116-10⟩
Journal of Virology, American Society for Microbiology, 2011, 85 (11), pp.5513-5523. ⟨10.1128/JVI.02116-10⟩
The recent development of a cell culture model of hepatitis C virus (HCV) infection based on the JFH-1 molecular clone has enabled discovery of new antiviral agents. Using a cell-based colorimetric screening assay to interrogate a 1,200-compound chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5980993b2b29973534a7f05f84b9a3e9
https://hal.science/hal-03295546
https://hal.science/hal-03295546