Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Christina Wheeler"'
Autor:
Gerhard Frey, Ana Paula G. Cugnetti, Haizhen Liu, Charles Xing, Christina Wheeler, Hwai Wen Chang, William J. Boyle, Jay M. Short
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
ABSTRACTEpithelial cell adhesion molecule (EpCAM) is a transmembrane glycoprotein that plays several roles in cancer biology. EpCAM is an attractive therapeutic target because of its expression in most solid tumors. However, targeting EpCAM has been
Externí odkaz:
https://doaj.org/article/7fc31e7a3b674b338e4ac1b2672d0edf
Autor:
Aritrick Chatterjee, Teodora Szasz, Milson Munakami, Ibrahim Karademir, Mohamed Shaif Yusufishaq, Spencer Martens, Christina Wheeler, Tatjana Antic, Stephen Thomas, Gregory S. Karczmar, Aytekin Oto
Publikováno v:
Academic Radiology.
Autor:
Ana Paula Cugnetti, Haizhen Liu, Patricia McNeeley, Christina Wheeler, Matthew Lucas, Charles Xing, Solmarie Joyner, Kyrie Johnson, Kathryn Woodard, Wei Zhou, Cathy Chang, Gerhard Frey, William J. Boyle, Jay M. Short
Publikováno v:
Cancer Research. 83:1871-1871
Human epidermal growth factor receptor 2 (HER2) is overexpressed in multiple cancers and is associated with poor prognosis. Despite the outstanding improvement in survival with the introduction of anti-HER2 therapies, therapeutic benefit is limited b
Autor:
Jian Chen, Christina Wheeler, Jing Wang, Matt Lucas, Haizhen Liu, Kyrie Johnson, Kathryn Woodard, Solmarie Joyner, Cathy Chang, William J. Boyle, Jay M. Short
Publikováno v:
Cancer Research. 83:4795-4795
The aberrant accumulation of senescent cells in aged and cancerous tissue triggers inflammatory signaling through a senescence-associated secretory phenotype (SASP), promoting aging and tumor progression. Pharmacologically, clearing senescent cells h
Autor:
Matthew Lucas, Ana Paula Cugnetti, Haizhen Liu, Charles Xing, Jing Wang, Patricia McNeeley, Christina Wheeler, Solmarie Joyner, Kyrie Johnson, Kathryn Woodard, Wei Zhou, Cathy Chang, Gerhard Frey, William J. Boyle, Jay M. Short
Publikováno v:
Cancer Research. 83:1879-1879
Nectin-4 is a Ca2+ independent immunoglobulin-like protein that is primarily involved in cell-cell adhesion. Nectin-4 is overexpressed in several tumor types, including breast, lung, urothelial, colorectal, pancreatic, and ovarian cancers. Overexpres
Autor:
Jian Chen, Jing Wang, Matt Lucas, Haizhen Liu, Christina Wheeler, Kyrie Johnson, Kathryn Woodard, Cathy Chang, Gerhard Frey, William J. Boyle, Jay M. Short
Publikováno v:
Cancer Research. 83:B022-B022
Cellular senescence is characterized by stable cell cycle arrest and a secretory program that modulates the tissue microenvironment. The aberrant accumulation of senescent cells in aged and cancerous tissue triggers inflammatory signaling through a s
Autor:
Aryo Sorayya, Christina Wheeler, Stacie Deaver, Kenneth Young, Michael Zeitz, James Smyth, Samy Lamouille
Publikováno v:
Cancer Research. 82:959-959
Epithelial-mesenchymal transition (EMT) is a normal process of embryonic development, stem cell differentiation, and wound healing. During EMT, epithelial cells lose apical-basal polarity, remodel intercellular junctions, and acquire migratory and in
Autor:
Christina Wheeler, Johnny Lopez
Get the most out of Microsoft Teams with this comprehensive and insightful resource Mastering Microsoft Teams: Creating a Hub for Successful Teamwork in Office 365 shows readers how to communicate intelligently and effectively within Microsoft's po
Autor:
Christina Wheeler, Jing Wang, Haizhen Liu, Ana Paula G. Cugnetti, William J. Boyle, Jay M. Short, Cathy Chang, Charles Xing, Gerhard Frey, Matthew Lucas
Publikováno v:
Cancer Research. 81:1870-1870
The use of CD3/target bispecific molecules has great therapeutic potential in oncology. This potential, however, is diminished due to severe cytokine release effects as well as serious on-target off-tumor toxicities. Conditionally Active Biologic (CA