Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Christina Weiler-Normann"'
Autor:
Laura Inhestern, Ramona Otto, Maja Brandt, David Zybarth, Ralf Oheim, Helke Schüler, Thomas S. Mir, Konstantinos Tsiakas, Payam Dibaj, Jana Zschüntzsch, Pamela M. Okun, Ute Hegenbart, Olaf Sommerburg, Christoph Schramm, Christina Weiler-Normann, Martin Härter, Corinna Bergelt
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-9 (2024)
Abstract Background Rare diseases are often complex, chronic and many of them life-shortening. In Germany, healthcare for rare diseases is organized in expert centers for rare diseases. Most patients additionally have regional general practicioners a
Externí odkaz:
https://doaj.org/article/f1b76e3f65e4416ea302a4a64bf74413
Autor:
Meike Mund, Natalie Uhlenbusch, Franziska Rillig, Christina Weiler-Normann, Theresia Herget, Christian Kubisch, Bernd Löwe, Christoph Schramm
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-10 (2023)
Abstract Background Centers for rare diseases serve as contact points for patients with complex, often undiagnosed complaints and persistent somatic symptoms of heterogeneous origin. Little is known about psychological distress of patients consulting
Externí odkaz:
https://doaj.org/article/4c4393a9f77a452f9b34ae83450290ce
Autor:
Lennart Hermanussen, Sibylle Lampalzer, Jan-Hendrik Bockmann, Annerose E. Ziegler, Felix Piecha, Maura Dandri, Sven Pischke, Friedrich Haag, Ansgar W. Lohse, Marc Lütgehetmann, Christina Weiler-Normann, Julian Schulze zur Wiesch
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Infections with hepatotropic viruses are associated with various immune phenomena. Hepatitis D virus (HDV) causes the most severe form of viral hepatitis. However, few recent data are available on non-disease-specific and non-organ-specific antibody
Externí odkaz:
https://doaj.org/article/27bea7066eb94ba3a61c0daa09da977d
Autor:
Lea Gerischer, Mona Mainert, Nils Wohmann, Ilja Kubisch, Ulrich Stölzel, Thomas Stauch, Sabine von Wegerer, Fabian Braun, Christina Weiler-Normann, Sabine Blaschke, Jorge Frank, Rajan Somasundaram, Eva Diehl-Wiesenecker
Publikováno v:
Healthcare, Vol 12, Iss 1, p 111 (2024)
Porphyrias, as most rare diseases, are characterized by complexity and scarcity of knowledge. A national registry in one of the largest European populations that prospectively collects longitudinal clinical and laboratory data are an important and ef
Externí odkaz:
https://doaj.org/article/856c4295d2f743f7b7f5096a1639a6f3
Publikováno v:
Autoimmunity, Vol 53, Iss 6, Pp 362-365 (2020)
In vitro, inhibition of the synthesis of guanosine monophosphate (GMP) by various drugs such as ribavirin, acyclovir, azathioprine, and mycophenolic acid leads to the formation of subcellular structures in cultured cells. Autoantibodies targeting the
Externí odkaz:
https://doaj.org/article/4317b6781b724411b2aaf0a1cbf7efbd
Autor:
Max Preti, Lena Schlott, David Lübbering, Daria Krzikalla, Anna-Lena Müller, Fenja A. Schuran, Tobias Poch, Miriam Schakat, Sören Weidemann, Ansgar W. Lohse, Christina Weiler-Normann, Marcial Sebode, Dorothee Schwinge, Christoph Schramm, Antonella Carambia, Johannes Herkel
Publikováno v:
JCI Insight, Vol 6, Iss 6 (2021)
The liver is an immune-privileged organ that can deactivate autoreactive T cells. Yet in autoimmune hepatitis (AIH), autoreactive T cells can defy hepatic control and attack the liver. To elucidate how tolerance to self-antigens is lost during AIH pa
Externí odkaz:
https://doaj.org/article/562c142691284b8baadaf1974c991cea
Autor:
Johannes Hartl, Rosa Miquel, Kalliopi Zachou, Guan-Wee Wong, Asma Asghar, Simon Pape, Marcial Sebode, Moritz Peiseler, Roman Zenouzi, Hanno Ehlken, Till Krech, Christina Weiler-Normann, Joost P.H. Drenth, Ye H. Oo, George Nikolaos Dalekos, Michael Heneghan, Christoph Schramm, Ansgar Wilhelm Lohse
Publikováno v:
JHEP Reports, Vol 2, Iss 3, Pp - (2020)
Background & Aims: High IgG levels are considered a hallmark of autoimmune hepatitis (AIH). A subgroup of patients with AIH has IgG within the normal range despite evidence of clinical disease activity. The clinical significance of this biomarker has
Externí odkaz:
https://doaj.org/article/bcca109810554658a87eabfcfdf0b496
Autor:
Marcial Sebode, Jennifer Wigger, Pamela Filpe, Lutz Fischer, Sören Weidemann, Till Krech, Christina Weiler-Normann, Moritz Peiseler, Johannes Hartl, Eva Tolosa, Johannes Herkel, Christoph Schramm, Ansgar W. Lohse, Philomena Arrenberg
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: Natural Killer T (NKT) cells are CD1d-restricted innate-like T cells that can rapidly release stored cytokines upon recognition of lipid antigens. In mice, type I NKT cells seem to promote liver inflammation, whereas type II NKT cells see
Externí odkaz:
https://doaj.org/article/54c5a1a0385d42709a8bec56900a540d
Autor:
Natalie Uhlenbusch, Bernd Löwe, Martin Härter, Christoph Schramm, Christina Weiler-Normann, Miriam K Depping
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0211343 (2019)
ObjectiveEmpirical evidence on depression and anxiety in patients with rare diseases is scarce but can help improve comprehensive treatment. The objectives of this study were to investigate the frequency of depression and anxiety in this heterogeneou
Externí odkaz:
https://doaj.org/article/0a8ed873f226442d863a71879f96c15f
Autor:
Thomas Horvatits, Julian Schulze zur Wiesch, Susanne Polywka, Gustav Buescher, Marc Lütgehetmann, Elaine Hussey, Karoline Horvatits, Sven Peine, Friedrich Haag, Marylyn M. Addo, Ansgar W. Lohse, Christina Weiler-Normann, Sven Pischke
Publikováno v:
Pathogens, Vol 9, Iss 9, p 755 (2020)
Background: Hepatitis E virus (HEV) has been associated with immunological phenomena. Their clinical significance, however, still needs to be clarified, that is, whether cryoglobulins or autoantibodies impact overt disease in HEV-infected individuals
Externí odkaz:
https://doaj.org/article/9d61bb3a6a9344bd8d2240ab1b4e1577