Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Christina Waldsich"'
Autor:
Christina Waldsich, Nora Sachsenmaier
Publikováno v:
RNA Biology. 10:71-82
RNA folding is an essential aspect underlying RNA-mediated cellular processes. Many RNAs, including large, multi-domain ribozymes, are capable of folding to the native, functional state without assistance of a protein cofactor in vitro. In the cell,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7c8ab4c5e6663a0533f095074e3f10d
https://doi.org/10.4161/rna.22492
https://doi.org/10.4161/rna.22492
Autor:
Katarzyna Mikolajczak, Alexander Serganov, Christina Waldsich, Song Cao, Anna Philips, Samuel C. Flores, Rhiju Das, Magdalena Rother, Dinshaw J. Patel, Christopher A. Lavender, Tomasz Puton, Fredrick Sijenyi, Irina Tuszynska, Michal J. Boniecki, John SantaLucia, Kevin M. Weeks, Marcin Skorupski, José Almeida Cruz, Lili Huang, Parin Sripakdeevong, Marc Frédérick Blanchet, Janusz M. Bujnicki, Shi-Jie Chen, Thomas Hermann, François Major, Nikolay V. Dokholyan, Tomasz Sołtysiński, Kristian Rother, Eric Westhof, Michael Wildauer, Neocles B. Leontis, Feng Ding, Véronique Lisi
Publikováno v:
RNA. 18:610-625
We report the results of a first, collective, blind experiment in RNA three-dimensional (3D) structure prediction, encompassing three prediction puzzles. The goals are to assess the leading edge of RNA structure prediction techniques; compare existin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bd4efb7aa9ecba8d38c9bc26d7f039c
https://doi.org/10.1261/rna.031054.111
https://doi.org/10.1261/rna.031054.111
Autor:
Christina Waldsich, Yun Yang, Dominik Muggenhumer, Nora Sachsenmaier, Yongfeng Jin, Nan Tian, Jingpei Bi, Michael F. Jantsch
Publikováno v:
Nucleic Acids Research
RNA editing by adenosine deaminases acting on RNAs (ADARs) can be both specific and non-specific, depending on the substrate. Specific editing of particular adenosines may depend on the overall sequence and structural context. However, the detailed m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f9c6c5a0286e489c409dc9fa25ac1e
https://doi.org/10.1093/nar/gkr144
https://doi.org/10.1093/nar/gkr144
Autor:
Christina Waldsich, Georgeta Zemora
Publikováno v:
RNA Biology. 7:634-641
RNA folding is the most essential process underlying RNA function. While significant progress has been made in understanding the forces driving RNA folding in vitro, exploring the rules governing intracellular RNA structure formation is still in its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe673b10f1590d8ad05467254bb0c41d
https://doi.org/10.4161/rna.7.6.13554
https://doi.org/10.4161/rna.7.6.13554
Publikováno v:
RNA Biology. 7:803-811
In yeast mitochondria the DEAD-box helicase Mss116p is essential for respiratory growth by acting as group I and group II intron splicing factor. Here we provide the first structure-based insights into how Mss116p assists RNA folding in vivo. Employi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2503e107fc07eb306622bfe12730169
https://doi.org/10.4161/rna.7.6.13484
https://doi.org/10.4161/rna.7.6.13484
Autor:
C. Lorenz, Bob Zimmermann, Tanja Gesell, Christina Waldsich, I. Bilusic, U. Schoeberl, Renée Schroeder, L. Rajkowitsch, A. von Haeseler
Publikováno v:
Nucleic Acids Research
An unexpectedly high number of regulatory RNAs have been recently discovered that fine-tune the function of genes at all levels of expression. We employed Genomic SELEX, a method to identify protein-binding RNAs encoded in the genome, to search for f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::984d27791d6449c026dd68f832536714
https://doi.org/10.1093/nar/gkq032
https://doi.org/10.1093/nar/gkq032
Autor:
Christina Waldsich, Anna Marie Pyle
Publikováno v:
Journal of Molecular Biology. 375:572-580
The D135 group II intron ribozyme follows a unique folding pathway that is direct and appears to be devoid of kinetic traps. During the earliest stages of folding, D135 collapses slowly to a compact intermediate, and all subsequent assembly events ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece2a9819eaecec11a47a237a34583c5
https://doi.org/10.1016/j.jmb.2007.10.052
https://doi.org/10.1016/j.jmb.2007.10.052
Publikováno v:
Journal of Molecular Biology. 366:1099-1114
The folding of group II intron ribozymes has been studied extensively under optimal conditions for self-splicing in vitro (42 degrees C and high magnesium ion concentrations). In these cases, the ribozymes fold directly to the native state by an appa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0b6f4781c78c6a43f12ad66e5160e6
https://doi.org/10.1016/j.jmb.2006.12.003
https://doi.org/10.1016/j.jmb.2006.12.003
Publikováno v:
Trends in Biochemical Sciences. 32:138-145
Group II introns are among the largest ribozymes in nature. They have a highly complex tertiary architecture that enables them to catalyze numerous processes, including self-splicing and transposition reactions that have probably contributed to the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6166570e4902bc1f2f008f88e09c15d4
https://doi.org/10.1016/j.tibs.2007.01.005
https://doi.org/10.1016/j.tibs.2007.01.005
Autor:
Anna Marie Pyle, Christina Waldsich
Publikováno v:
Nature Structural & Molecular Biology. 14:37-44
Ribozymes derived from the group II intron ai5gamma collapse to a compact intermediate, folding to the native state through a slow, direct pathway that is unperturbed by kinetic traps. Molecular collapse of ribozyme D135 requires high magnesium conce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7202324cc210f4324cf31e1e76927616
https://doi.org/10.1038/nsmb1181
https://doi.org/10.1038/nsmb1181