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pro vyhledávání: '"Christina Terragni"'
Autor:
James William Bryson, Wai Leung Lau, John A. Brailsford, Miguel Moreta, Julie Su, Virginie Lafont, Martin C. Wright, Michael J. Smith, H. Nicholas Marsh, Anthony Barros, Sanjeev Gangwar, Jason Pinckney, Qiang Cong, Alban Allentoff, Christina Terragni, Dasa Lipovsek, Pete Z. Cotter, Michael Wallace, Irvith M. Carvajal, Cris Hollander, Wenying Li, O'neil Steven, Lifei Wang
Publikováno v:
Protein Engineering, Design and Selection
Tumor-specific delivery of cytotoxic agents remains a challenge in cancer therapy. Antibody–drug conjugates (ADC) deliver their payloads to tumor cells that overexpress specific tumor-associated antigens—but the multi-day half-life of ADC leads t