Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Christina T. LaGamma"'
Autor:
Christina T. LaGamma, William W. Tang, Ashlea A. Morgan, Josephine Cecelia McGowan, Rebecca A. Brachman, Christine A. Denny
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Ketamine has been found to have rapid, long-lasting antidepressant effects in treatment-resistant (TR) patients with major depressive disorder (MDD). Recently, we have also shown that ketamine acts as a prophylactic to protect against the development
Externí odkaz:
https://doaj.org/article/cade3c66031a49a2b5f3c3db65759f7f
Autor:
Josephine C. McGowan, Liliana R. Ladner, Claire X. Shubeck, Juliana Tapia, Christina T. LaGamma, Amanda Anqueira-González, Ariana DeFrancesco, Briana K. Chen, Holly C. Hunsberger, Ezra J. Sydnor, Ryan W. Logan, Tzong-Shiue Yu, Steven G. Kernie, Christine A. Denny
Publikováno v:
bioRxiv
INTRODUCTIONTraumatic brain injury (TBI) is a debilitating neurological disorder caused by an impact to the head by an outside force. TBI results in persistent cognitive impairments, including fear generalization, the inability to distinguish between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::444a12477f569e1d976efac29d8e85bd
https://europepmc.org/articles/PMC10002673/
https://europepmc.org/articles/PMC10002673/
Autor:
Briana K. Chen, Donald W. Landry, Shi-Xian Deng, Xiaoming Xu, Christine A. Denny, Denis J. David, Victor M. Luna, Christina T LaGamma, Indira Mendez-David, Rebecca A. Brachman, Alain M. Gardier, Abhishek Shah, Thomas B. Cooper, Raymond F. Suckow
Publikováno v:
Neuropsychopharmacology
Enhancing stress resilience in at-risk populations could significantly reduce the incidence of stress-related psychiatric disorders. We have previously reported that the administration of (R,S)-ketamine prevents stress-induced depressive-like behavio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ab22efe3b7a5a1bf0cf35723e91cde
https://doi.org/10.1038/s41386-020-0714-z
https://doi.org/10.1038/s41386-020-0714-z
Autor:
Thomas B. Cooper, Xiaoming Xu, Raymond F. Suckow, Rebecca A. Brachman, Shi-Xian Deng, Donald W. Landry, Briana K. Chen, Christine A. Denny, Christina T. LaGamma
BACKGROUNDFemales are more likely than males to develop major depressive disorder (MDD) after exposure to stress. We previously reported that the administration of (R,S)-ketamine before stress can prevent stress-induced depressive-like behavior in ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae5263d19a46b0837bf0fc338436096d
Autor:
Josephine C. McGowan, Christina T. LaGamma, Christine A. Denny, Alessia Mastrodonato, Omid Cohensedgh, Holly C. Hunsberger
Publikováno v:
Behavioural Brain Research. 378:112238
Individuals with peripheral inflammation are a particularly vulnerable population for developing depression and are also more resistant towards traditional antidepressants. This signals the need for novel drugs that can effectively treat this patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ccc30d338882d790b998ffea4b6dd0a
https://doi.org/10.1016/j.bbr.2019.112238
https://doi.org/10.1016/j.bbr.2019.112238
Autor:
Rebecca A. Brachman, Alessia Mastrodonato, Christina T. LaGamma, Christine A. Denny, Alfred J. Robison, Ina Pavlova, Randy Martinez
Background We previously reported that a single injection of ketamine prior to stress protects against the onset of depressive-like behavior and attenuates learned fear. However, the molecular pathways and brain circuits underlying ketamine-induced s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f3049d6a6dd5d68f05b4a203629500
https://europepmc.org/articles/PMC6107435/
https://europepmc.org/articles/PMC6107435/
Autor:
Rebecca A. Brachman, Christine A. Denny, Alessia Mastrodonato, Alexander Kitayev, Niven R. Narain, Michael A. Kiebish, Christina T. LaGamma, Josephine C. McGowan, Collin Hill
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 43(9)
Recently, we have shown that ketamine given prior to stress exposure protects against the development of depressive-like behavior in mice. These data suggest that it may be possible to prevent the induction of affective disorders before they develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3296140463acb2c2caee7d597a9ab40
https://pubmed.ncbi.nlm.nih.gov/29599484
https://pubmed.ncbi.nlm.nih.gov/29599484
Autor:
Yuval Neria, Rebecca A. Brachman, Sean C. Lim, Melina Tsitsiklis, Josephine C. McGowan, Christine A. Denny, Christina T. LaGamma
Ketamine has been reported to be an efficacious antidepressant for major depressive disorder and posttraumatic stress disorder. Most recently, ketamine has also been shown to be prophylactic against stress-induced depressive-like behavior in mice. It
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f291b8fdd26f8ffa6a128292df78cd5d
https://europepmc.org/articles/PMC5518899/
https://europepmc.org/articles/PMC5518899/