Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Christina Stannek"'
Publikováno v:
British Journal of Pharmacology. 146:958-963
The kallikrein–kinin system is subdivided into the plasma and tissue–kallikrein–kinin system, with bradykinin (BK) and kallidin (KAL) (Lys0-bradykinin) as functional peptides. This occurs in both humans and other mammals. Both peptides are rele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2200b60553f3eebc44b7e964a19e8abb
https://doi.org/10.1038/sj.bjp.0706409
https://doi.org/10.1038/sj.bjp.0706409
Publikováno v:
Biochemical Pharmacology. 64:645-648
The use of the HDL-elevating drug nicotinic acid in the treatment and prevention of atherosclerotic disease is limited by the frequent induction of skin flushing. The therapeutic effects of nicotinic acid are attributed to inhibition of lipolysis in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a7e7fb2b15eef777f726feccf7ea58
https://doi.org/10.1016/s0006-2952(02)01220-0
https://doi.org/10.1016/s0006-2952(02)01220-0
Autor:
Christina Stannek, Pieter A. M. van der Klein, and Anna Lorenzen, Miriam de Groote, Jacobien von Frijtag Drabbe Künzel, Erica W. van Tilburg, Ad P. IJzerman
Publikováno v:
Journal of Medicinal Chemistry. 44:2966-2975
New N,5'-di- and N,2,5'-trisubstituted adenosine derivatives were synthesized in good overall yields. Appropriate 5-O-alkyl-substituted ribose moieties were coupled to 6-chloropurine or 2,6-dichloropurine via Vorbrüggen's glycosylation method. Subse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b61621e498e40b7eb40981dba28286c5
https://doi.org/10.1021/jm001114o
https://doi.org/10.1021/jm001114o
Autor:
Sauro Vittori, Gloria Cristalli, Christina Stannek, Stefano Costanzi, Anna Lorenzen, Adriaan P. IJzerman, Jakobien K. Von Frijtag Drabbe Kunzel, Rosaria Volpini
Publikováno v:
Journal of Medicinal Chemistry. 43:250-260
A number of cycloalkyl substituents (from C-3 to C-8) have been introduced on the 6-amino group of adenosine, 1-deazaadenosine, and 2'-deoxyadenosine, bearing or not a chlorine atom at the 2-position, to evaluate the influence on the A(1) and A(2A) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d871d8f92234ee6732394301c6e7e59
https://doi.org/10.1021/jm9911231
https://doi.org/10.1021/jm9911231
Autor:
Christina Stannek, Sauro Vittori, Gloria Cristalli, Jakobien K. Von Frijtag Drabbe Kunzel, Rosaria Volpini, Anna Lorenzen, Adriaan P. IJzerman, Stefano Costanzi
Publikováno v:
ChemInform. 31
A number of cycloalkyl substituents (from C-3 to C-8) have been introduced on the 6-amino group of adenosine, 1-deazaadenosine, and 2‘-deoxyadenosine, bearing or not a chlorine atom at the 2-position, to evaluate the influence on the A1 and A2A aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94a60c7f5ea5adc01fef813c498e8c4f
https://doi.org/10.1002/chin.200016239
https://doi.org/10.1002/chin.200016239
Autor:
Ulrich, Hilgenfeldt, Christina, Stannek, Martina, Lukasova, Martina, Schnölzer, Sabina, Lewicka
Publikováno v:
British journal of pharmacology. 146(7)
The kallikrein-kinin system is subdivided into the plasma and tissue-kallikrein-kinin system, with bradykinin (BK) and kallidin (KAL) (Lys(0)-bradykinin) as functional peptides. This occurs in both humans and other mammals. Both peptides are released
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5a71d7c71710d1a2b536581029aae6fa
https://pubmed.ncbi.nlm.nih.gov/16231010
https://pubmed.ncbi.nlm.nih.gov/16231010
Autor:
P. A. M. van der Klein, J. Brussee, T. van Herk, A. M. C. H. van den Nieuwendijk, Adriaan P. IJzerman, Christina Stannek, Anna Lorenzen, and A. Burmeister
Publikováno v:
Journal of medicinal chemistry. 46(18)
Nicotinic acid as a hypolipidemic agent appears unique due to its potential to increase HDL cholesterol levels to a greater extent than other drugs. However, it has some side effects, among which severe skin flushing is the most frequent and often li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75259de566098f1a304e2d24a3bbe42b
https://pubmed.ncbi.nlm.nih.gov/12930155
https://pubmed.ncbi.nlm.nih.gov/12930155
Autor:
Heidrun Lang, Christina Stannek, Anna Lorenzen, Viktor Andrianov, Ivars Kalvinsh, Ulrich Schwabe
Publikováno v:
Molecular pharmacology. 59(2)
Nicotinic acid is a lipid-lowering agent widely used to treat hypertriglyceridemia and to elevate low high density lipoprotein levels. However, the underlying mechanisms are poorly understood. In this study, G protein activation by nicotinic acid and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f3123e35d2da835b9c0a11d5ce96b4
https://pubmed.ncbi.nlm.nih.gov/11160872
https://pubmed.ncbi.nlm.nih.gov/11160872
Publikováno v:
Journal of Hypertension. 30:e81
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::909a9525460d01d27b7300826c5166e2
https://doi.org/10.1097/01.hjh.0000420160.01507.5a
https://doi.org/10.1097/01.hjh.0000420160.01507.5a