Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Christina Snider"'
Driver mutation zygosity is a critical factor in predicting clonal hematopoiesis transformation risk
Autor:
Ashwin Kishtagari, M. A. Wasay Khan, Yajing Li, Caitlyn Vlasschaert, Naimisha Marneni, Alexander J. Silver, Kelly von Beck, Travis Spaulding, Shannon Stockton, Christina Snider, Andrew Sochacki, Dixon Dorand, Taralynn M. Mack, P. Brent Ferrell, Yaomin Xu, Cosmin A. Bejan, Michael R. Savona, Alexander G. Bick
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-6 (2024)
Abstract Clonal hematopoiesis (CH) can be caused by either single gene mutations (eg point mutations in JAK2 causing CHIP) or mosaic chromosomal alterations (e.g., loss of heterozygosity at chromosome 9p). CH is associated with a significantly increa
Externí odkaz:
https://doaj.org/article/8eae0d4d2063482883822364b8d4b942
Autor:
Christina Snider, Hina Budhwani, Melissa Logue, Parul Goyal, Kelly Pugh, Harvey Murff, Adetola Kassim, Reena Jayani
Publikováno v:
Innovation in Aging. 6:691-692
Increasingly, older adults are receiving hematopoietic cell transplant (HCT) and chimeric antigen receptor T-cell therapy (CAR-T), intensive therapies for treatment of hematologic cancers which typically require prolonged hospital admissions. Older a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec407517cc082a93e90b3670e390879a
https://doi.org/10.1093/geroni/igac059.2536
https://doi.org/10.1093/geroni/igac059.2536
Autor:
Jaroslaw P. Maciejewski, Shafia Rahman, Bhumika J. Patel, Hetty E. Carraway, Mohammad Fahad B Asad, Yasunobu Nagata, Mikkael A. Sekeres, Valeria Visconte, Ashwin Kishtagari, Vera Adema, Sunisa Kongkiatkamon, Christina Snider, Hassan Awada, Cassandra M Kerr, Amy C Graham, Jibran Durrani
Publikováno v:
Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ec26c523588fc4fc2110763f24bec63
https://doi.org/10.1038/s41375-019-0555-0
https://doi.org/10.1038/s41375-019-0555-0
Publikováno v:
Adult CNS Radiation Oncology ISBN: 9783319428772
Choroid plexus tumors (CPT) are rare tumors of the neuroepithelial tissue of the brain that are most common in young children. In adults, they arise most frequently in the fourth ventricle, often presenting with hydrocephalus due to overproduction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dcfa9c582a809a61bb91583bccac8c3
https://doi.org/10.1007/978-3-319-42878-9_20
https://doi.org/10.1007/978-3-319-42878-9_20
Publikováno v:
Open Forum Infectious Diseases
Background Herpes simplex virus (HSV) is the most common cause of infectious encephalitis in the United States. While early treatment with acyclovir has improved acute management, long-term morbidity and mortality remain high and warrant further char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7874393237deabfbf165d5972668b36c
http://europepmc.org/articles/PMC6809179
http://europepmc.org/articles/PMC6809179
Autor:
Mikkael A. Sekeres, Torsten Haferlach, Anjali S. Advani, Kevin Fung, Vera Adema, Hetty E. Carraway, Christina Snider, Hassan Awada, Michael R. Savona, Sunisa Kongkiatkamon, Jennifer S. Carew, Stephan Hutter, Cassandra M Kerr, Jaroslaw P. Maciejewski, Jibran Durrani, Yogenthiran Saunthararajah, James G. Phillips, Manja Meggendorfer, Valeria Visconte, Kevin R. Kelly, Francesca Gould, Steffan T. Nawrocki
Publikováno v:
Blood. 134:1281-1281
Lenalidomide (LEN) has established a new paradigm of targeted therapy in MDS. The mechanistic underpinnings of LEN efficacy are related to the synthetic lethality of this agent through its ability to bind cereblon (CRBN). LEN induces degradation of C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c65c1efbb2e00d9c07f122d60c67f17e
https://doi.org/10.1182/blood-2019-129196
https://doi.org/10.1182/blood-2019-129196
Autor:
Torsten Haferlach, Yasunobu Nagata, Stephan Hutter, Thomas LaFramboise, Mikkael A. Sekeres, Claudia Haferlach, Vera Adema, Wencke Walter, Jaroslaw P. Maciejewski, Valeria Visconte, Cassandra M Kerr, Manja Meggendorfer, Christina Snider
Publikováno v:
Blood. 134:1703-1703
Monosomy (-7) and deletions of the long arm of chromosome 7 (del7q) are frequently found in patients with myeloid neoplasms, suggesting a crucial role of this region in disease pathogenicity. -7/del7q conveys a poor prognosis and no targeted therapie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c4ef9aeba61f1bd36cf4701980dcc03
https://doi.org/10.1182/blood-2019-126866
https://doi.org/10.1182/blood-2019-126866
Autor:
Milo Co, Tomas Radivoyevitch, Hetty E. Carraway, Bhumika J. Patel, Hassan Awada, Aaron T. Gerds, Vera Adema, Valeria Visconte, Sudipto Mukherjee, Francesca Gould, Teodora Kuzmanovic, Sunisa Kongkiatkamon, Cassandra M Kerr, Jaroslaw P. Maciejewski, Kevin Fung, Mikkael A. Sekeres, Christina Snider, Anjali S. Advani, Aziz Nazha
Publikováno v:
Blood. 134:2696-2696
One strategy to improve precision medicine in acute myeloid leukemia (AML) is to further our understanding of the biological factors that influence pharmacologic efficacy. In a recent study, whole transcriptome analysis was conducted using pre- and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40378645cc24032214f623d6bae17708
https://doi.org/10.1182/blood-2019-126311
https://doi.org/10.1182/blood-2019-126311
Autor:
Hetty E. Carraway, Cassandra M Kerr, Hassan Awada, Allison Noe, Yuriy Fedorov, Steffan T. Nawrocki, Daniel J. Lindner, Heesun J. Rogers, Bartlomiej P Przychodzen, Anjali S. Advani, Yvonne Parker, Kevin R. Kelly, James G. Phillips, Vera Adema, Rachel Toth, Valeria Visconte, Drew J. Adams, Anand D. Tiwari, Jennifer S. Carew, Mikkael A. Sekeres, Christina Snider, Jaroslaw P. Maciejewski
Publikováno v:
Blood. 134:564-564
SF3B1 mutations disrupt normal pre-mRNA splicing to cause disease. Drugs inhibiting the interaction between the SF3b complex and RNA or agents degrading auxiliary splicing factors are being tested as new avenues for targeted therapy in myeloid neopla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f64c075751b225756abda29cc7a7f6f5
https://doi.org/10.1182/blood-2019-129189
https://doi.org/10.1182/blood-2019-129189
Autor:
Yasunobu Nagata, Hetty E. Carraway, Hassan Awada, Valeria Visconte, Christina Snider, Milo Co, Sunisa Kongkiatkamon, Vera Adema, Jaroslaw P. Maciejewski, Cassandra M Kerr, Francesca Gould, Mikkael A. Sekeres, Jibran Durrani, Kevin Fung
Publikováno v:
Blood. 134:5043-5043
Systematic application of NGS has led to the discovery of a myriad of somatic mutations. One important class of genes affected by mutations in myeloid neoplasia (MN) is involved in epigenetic regulation either directly by modifying DNA or by enzymes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f153ce2046cca54d00fe1583f4fa7570
https://doi.org/10.1182/blood-2019-130986
https://doi.org/10.1182/blood-2019-130986