Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Christina Schuelein‐Voelk"'
Autor:
Maria Körner, Susanne R Meyer, Gabriella Marincola, Maximilian J Kern, Clemens Grimm, Christina Schuelein-Voelk, Utz Fischer, Kay Hofmann, Alexander Buchberger
Publikováno v:
eLife, Vol 12 (2023)
The ATPase p97 (also known as VCP, Cdc48) has crucial functions in a variety of important cellular processes such as protein quality control, organellar homeostasis, and DNA damage repair, and its de-regulation is linked to neuromuscular diseases and
Externí odkaz:
https://doaj.org/article/088885aee7b845c49c72985154a87b7b
Autor:
Christoph Otto, Carolin Kastner, Stefanie Schmidt, Konstantin Uttinger, Apoorva Baluapuri, Sarah Denk, Mathias T. Rosenfeldt, Andreas Rosenwald, Florian Roehrig, Carsten P. Ade, Christina Schuelein‐Voelk, Markus E. Diefenbacher, Christoph‐Thomas Germer, Elmar Wolf, Martin Eilers, Armin Wiegering
Publikováno v:
Molecular Oncology, Vol 16, Iss 15, Pp 2788-2809 (2022)
Ribosomal biogenesis and protein synthesis are deregulated in most cancers, suggesting that interfering with translation machinery may hold significant therapeutic potential. Here, we show that loss of the tumor suppressor adenomatous polyposis coli
Externí odkaz:
https://doaj.org/article/86ca5923c6f34dcb85b7467dac7cbb83
Autor:
Sebastian Blättner, Sudip Das, Kerstin Paprotka, Ursula Eilers, Markus Krischke, Dorothee Kretschmer, Christian W Remmele, Marcus Dittrich, Tobias Müller, Christina Schuelein-Voelk, Tobias Hertlein, Martin J Mueller, Bruno Huettel, Richard Reinhardt, Knut Ohlsen, Thomas Rudel, Martin J Fraunholz
Publikováno v:
PLoS Pathogens, Vol 12, Iss 9, p e1005857 (2016)
Community-acquired (CA) Staphylococcus aureus cause various diseases even in healthy individuals. Enhanced virulence of CA-strains is partly attributed to increased production of toxins such as phenol-soluble modulins (PSM). The pathogen is internali
Externí odkaz:
https://doaj.org/article/9698c7667459459cb09fc76121b08fa8
Autor:
Christoph Otto, Carolin Kastner, Stefanie Schmidt, Konstantin Uttinger, Apoorva Baluapuri, Sarah Denk, Mathias T. Rosenfeldt, Andreas Rosenwald, Florian Roehrig, Carsten P. Ade, Christina Schuelein‐Voelk, Markus E. Diefenbacher, Christoph‐Thomas Germer, Elmar Wolf, Martin Eilers, Armin Wiegering
Publikováno v:
Molecular Oncology. 16:2788-2809
Ribosomal biogenesis and protein synthesis are deregulated in most cancers, suggesting that interfering with translation machinery may hold significant therapeutic potential. Here, we show that loss of the tumor suppressor adenomatous polyposis coli
Autor:
Michaela Reissland, Oliver Hartmann, Saskia Tauch, Cristian Prieto-Garcia, Clemens Schulte, Daniel Solvie, Sinah Loebbert, Anne-Claire Jacomin, Marina Pesic, Jeroen M. Bugter, Christina Schuelein-Voelk, Carmina T. Fuss, Nikolet Pahor, Carsten Ade, Viktoria Buck, Michael Potente, Vivian Li, Gerti Beliu, Armin Wiegering, Eliya Bitman-Lotan, Tom Grossmann, Mathias Rosenfeldt, Martin Eilers, Hans Maric, Madelon M. Maurice, Florian Greten, Ivan Dikič, Amir Orian, Peter Gallant, Markus E. Diefenbacher
SummaryThe contribution of deubiquitylating enzymes to β-Catenin stabilisation in intestinal stem cells and colorectal cancer (CRC) is poorly understood. Here, we report the deubiquitylase USP10 as an APC-truncation- specific enhancer of β-Catenin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07cbccc13dc3cb445f4a5957beac5545
https://doi.org/10.1101/2023.02.10.527983
https://doi.org/10.1101/2023.02.10.527983
Autor:
Cristian Prieto-Garcia, C. Muench, Mathias Rosenfeldt, Ivan Dikic, Oliver Hartmann, Christina Schuelein-Voelk, Marco A. Calzado, Michaela Reissland, S. Bozkurt, C. T. Fuss, A. Buchberger, Fabian Braun, Markus E. Diefenbacher
Oncogenic transformation of lung epithelial cells is a multi-step process, frequently starting with the inactivation of tumor suppressors and subsequent activating mutations in proto-oncogenes, such as members of the PI3K or MAPK family. Cells underg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d83c87f9197ec900379dd7c0114983a
https://doi.org/10.1101/2021.09.06.459088
https://doi.org/10.1101/2021.09.06.459088
Autor:
Christina Schuelein-Voelk, Michaela Reissland, Cristian Prieto-Garcia, Mathias Rosenfeldt, Markus E. Diefenbacher, E. Gebhard-Hartmann, C. Muench, Kevin Klann, Bülent Polat, Oliver Hartmann, Thomas Fischer, M. Flentje
BackgroundDespite advances in treatment of patients with non-small cell lung cancer, carriers of certain genetic alterations are prone to failure. One such factor frequently mutated, is the tumor suppressor PTEN. These tumors are supposed to be more
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6a0ae59123a4d09e17d5dd38329ea17
https://doi.org/10.1101/2021.07.24.453632
https://doi.org/10.1101/2021.07.24.453632
Autor:
Knut Ohlsen, Martin Fraunholz, Christina Schuelein-Voelk, Bruno Huettel, Dorothee Kretschmer, Ursula Eilers, Marcus Dittrich, Martin J. Mueller, Kerstin Paprotka, Tobias Müller, Christian W. Remmele, Sudip Das, Tobias Hertlein, Richard Reinhardt, Thomas Rudel, Markus Krischke, Sebastian Blättner
Publikováno v:
PLoS Pathogens, Vol 12, Iss 9, p e1005857 (2016)
PLoS Pathogens
PLoS Pathogens
Community-acquired (CA) Staphylococcus aureus cause various diseases even in healthy individuals. Enhanced virulence of CA-strains is partly attributed to increased production of toxins such as phenol-soluble modulins (PSM). The pathogen is internali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2b5c8258e5567d58112197f4e78ceb1
https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/18038
https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/18038