Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Christina Schlagheck"'
Autor:
Kristaps Kairišs, Natalia Sokolova, Lucie Zilova, Christina Schlagheck, Robert Reinhardt, Tilo Baumbach, Tomáš Faragó, Thomas van de Kamp, Joachim Wittbrodt, Venera Weinhardt
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The development of an organism is orchestrated by the spatial and temporal expression of genes. Accurate visualisation of gene expression patterns in the context of the surrounding tissues offers a glimpse into the mechanisms that drive morp
Externí odkaz:
https://doaj.org/article/a82da212777549298f15fd4846e6cadb
Autor:
Lucie Zilova, Venera Weinhardt, Tinatini Tavhelidse, Christina Schlagheck, Thomas Thumberger, Joachim Wittbrodt
Publikováno v:
eLife, Vol 10 (2021)
Organoids derived from pluripotent stem cells promise the solution to current challenges in basic and biomedical research. Mammalian organoids are however limited by long developmental time, variable success, and lack of direct comparison to an in vi
Externí odkaz:
https://doaj.org/article/4099570372f14de78d728ebd974ffd4f
Autor:
Parysatis Sachs, Dong Ding, Philipp Bergmaier, Boris Lamp, Christina Schlagheck, Florian Finkernagel, Andrea Nist, Thorsten Stiewe, Jacqueline E. Mermoud
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Tight regulation of retrotransposons such as endogenous retroviruses (ERVs) is essential for genome and transcriptome integrity. Here, the authors show that the ATPase function of the chromatin remodeler SMARCAD1 facilitates the binding of KAP1 to ER
Externí odkaz:
https://doaj.org/article/0e710344df08499391e740770a34e858
Autor:
Christina Schlagheck, Andrea Nist, Boris Lamp, Thorsten Stiewe, Florian Finkernagel, Philipp Bergmaier, Jacqueline E. Mermoud, Dong Ding, Parysatis Sachs
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications
Nature Communications
Endogenous retroviruses (ERVs) can confer benefits to their host but present a threat to genome integrity if not regulated correctly. Here we identify the SWI/SNF-like remodeler SMARCAD1 as a key factor in the control of ERVs in embryonic stem cells.
Autor:
Lucie Zilova, Venera Weinhardt, Tinatini Tavhelidse, Christina Schlagheck, Thomas Thumberger, Joachim Wittbrodt
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Organoids derived from pluripotent stem cells promise the solution to current challenges in basic and biomedical research. Mammalian organoids are however limited by long developmental time, variable success, and lack of direct comparison to an in vi