Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Christina Schönherr"'
Autor:
Damini Chand, Yasuo Yamazaki, Kristina Ruuth, Christina Schönherr, Tommy Martinsson, Per Kogner, Edward F. Attiyeh, John Maris, Olena Morozova, Marco A. Marra, Miki Ohira, Akira Nakagawara, Per-Erik Sandström, Ruth H. Palmer, Bengt Hallberg
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 2, Pp 373-382 (2013)
SUMMARY Neuroblastoma is a childhood extracranial solid tumour that is associated with a number of genetic changes. Included in these genetic alterations are mutations in the kinase domain of the anaplastic lymphoma kinase (ALK) receptor tyrosine kin
Externí odkaz:
https://doaj.org/article/f61c5b972ea944289363faff0ad11f9f
Autor:
Bengt Hallberg, Ruth H. Palmer, Kristina Ruuth, Joel Weinmar, Christina Schönherr, Sattu Kamaraj, Per Kogner, Magnus Hansson, Helena Caren, Jonas Abrahamsson, Therese Eriksson, Tommy Martinsson
Supplementary Figure Legend from Appearance of the Novel Activating F1174S ALK Mutation in Neuroblastoma Correlates with Aggressive Tumor Progression and Unresponsiveness to Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d88518673d367946424c79fada0e8e
https://doi.org/10.1158/0008-5472.22388453
https://doi.org/10.1158/0008-5472.22388453
Autor:
Camilla Sjögren, Fredrik Hugosson, Dmitry Popichenko, Christina Schönherr, Hanh Nguyen, Yasuo Yamazaki, Mahsa Fallah, Georg Wolfstetter, Murat Dogru, Bengt Hallberg, Ruth H. Palmer
Publikováno v:
Development. 140:3156-3166
The Jelly belly (Jeb)/Anaplastic Lymphoma Kinase (Alk) signalling pathway regulates myoblast fusion in the circular visceral mesoderm (VM) of Drosophila embryos via specification of founder cells. However, only a limited number of target molecules fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8436fc87316c55f0b776a39b6b7a7ec0
https://doi.org/10.1242/dev.094466
https://doi.org/10.1242/dev.094466
Autor:
Jianmin Wu, Christina Schönherr, Ganesh Umapathy, James R. Fuchs, Kristina Ruuth, Barbara Witek, Roger J. Daly, Ruth H. Palmer, Pui-Kai Li, Kamaraj Sattu, Damini Chand, Falko Hochgräfe, Fredrik Hugosson, Bengt Hallberg
Publikováno v:
The Febs Journal
Activation of the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase is a key oncogenic mechanism in a growing number of tumor types. In the majority of cases, ALK is activated by fusion with a dimerizing partner protein as a result of chromos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df0e3bc69829203c2e136ffad8df389
http://europepmc.org/articles/PMC3892176
http://europepmc.org/articles/PMC3892176
Autor:
Marco A. Marra, Bengt Hallberg, Per Kogner, Tommy Martinsson, Edward F. Attiyeh, Akira Nakagawara, Yasuo Yamazaki, Christina Schönherr, Miki Ohira, John M. Maris, Per-Erik Sandström, Kristina Ruuth, Damini Chand, Olena Morozova, Ruth H. Palmer
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 2, Pp 373-382 (2013)
Disease Models & Mechanisms
Disease Models & Mechanisms
SummaryNeuroblastoma is a childhood extracranial solid tumor which is associated with a number of genetic changes. Included in these genetic alterations are mutations in the kinase domain of the Anaplastic Lymphoma Kinase (ALK) receptor tyrosine kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebbb2fc7d5a034d198248926585fe047
http://dmm.biologists.org/content/6/2/373
http://dmm.biologists.org/content/6/2/373
Autor:
Kristina Ruuth, Tommy Martinsson, Cai-Ling Wang, Hai-Ling Yang, James G. Christensen, Christina Schönherr, Sattu Kamaraj, Ruth H. Palmer, Anna Djos, Bengt Hallberg, Valérie Combaret
Publikováno v:
Oncogene. 31:5193-5200
Neuroblastoma is a neural crest-derived embryonal tumour of the postganglionic sympathetic nervous system and a disease with several different chromosomal gains and losses, which include MYCN-amplified neuroblastoma on chromosome 2, deletions of part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02eae819b9efd3511905a2614a12fe07
https://doi.org/10.1038/onc.2012.12
https://doi.org/10.1038/onc.2012.12
Autor:
Kristina Ruuth, Yasuo Yamazaki, James G. Christensen, Bengt Hallberg, Christina Schönherr, Ruth H. Palmer, Therese Eriksson
Publikováno v:
Biochemical Journal. 440:405-414
Mutations in the kinase domain of ALK (anaplastic lymphoma kinase) have recently been shown to be important for the progression of the childhood tumour neuroblastoma. In the present study we investigate six of the putative reported constitutively act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79aee012d2a96349f215ec624a3b3034
https://doi.org/10.1042/bj20101796
https://doi.org/10.1042/bj20101796
Autor:
Therese Eriksson, Marc Vigny, Christian Ottmann, Christina Schönherr, Ruth H. Palmer, Sattu Kamaraj, Kristina Ruuth, Bengt Hallberg, Yasuo Yamazaki, Valérie Combaret
Publikováno v:
Translational Oncology, 4(4), 258-265. Neoplasia Press
Activating mutations in the kinase domain of anaplastic lymphoma kinase (ALK) have recently been shown to be an important determinant in the genetics of the childhood tumor neuroblastoma. Here we discuss an in-depth analysis of one of the reported ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6abce314188d4031654812b9c7b9f68
https://doi.org/10.1593/tlo.11139
https://doi.org/10.1593/tlo.11139
Publikováno v:
Oncogene. 29:2817-2830
Many different types of cancer originate from aberrant signaling from the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase (RTK), arising through different translocation events and overexpression. Further, activating point mutations in the A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c679e4e0e2b5f96e572f482201672f7
https://doi.org/10.1038/onc.2010.27
https://doi.org/10.1038/onc.2010.27
Autor:
Abeer El Wakil, Laura Danielson, Xianming Deng, Ganesh Umapathy, Bengt Hallberg, Mikael Johansson, Nathanael S. Gray, Louis Chesler, Christina Schönherr, Barbara Witek, Ruth H. Palmer, Samuel Kvarnbrink, Kristina Ruuth
Publikováno v:
Science signaling. 7(349)
Anaplastic lymphoma kinase (ALK) is an important molecular target in neuroblastoma. Although tyrosine kinase inhibitors abrogating ALK activity are currently in clinical use for the treatment of ALK-positive (ALK(+)) disease, monotherapy with ALK tyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a97a0b9e07b3d49f388426287cde3b9
https://pubmed.ncbi.nlm.nih.gov/25351247
https://pubmed.ncbi.nlm.nih.gov/25351247